Recent Advances in Solution-Phase Multicomponent Methodology for the Synthesis of Heterocyclic Compounds

ChemInform ◽  
2003 ◽  
Vol 34 (40) ◽  
Author(s):  
Romano V. A. Orru ◽  
Michiel de Greef
Keyword(s):  
Heterocyclic Compounds ◽  
Solution Phase ◽  
Recent Advances

A REVIEW ON RECENT ADVANCES IN CHEMISTRY, SYNTHESIS AND BIOLOGICAL APPLICATIONS OF ISATIN DERIVATIVES

2018 ◽  
pp. 16-22
Author(s):  
Shukla PK ◽  
Singh MP ◽  
Patel R
Keyword(s):  
Heterocyclic Compounds ◽  
Biologically Active ◽  
Biological Applications ◽  
Plant Origin ◽  
Recent Past ◽  
Pharmacological Activities ◽  
Naturally Occurring ◽  
Recent Advances ◽  
Biological Aspects ◽  
Isatin Derivatives

Indole and its derivatives have engaged a unique place in the chemistry of nitrogen heterocyclic compounds. The recognition of the plant growthhormone, heteroauxin, the significant amino acids, tryptamine & tryptophan and anti-inflammatory drug, indomethacine are the imperativederivatives of indole which have added stimulus to this review work. Isatin (1H-indole-2,3-dione), an indole derivative of plant origin. Althoughit is a naturally occurring compound, but was synthesized by Erdmann and Laurent in 1840 before it was found in nature. Isatin is a versatileprecursor for many biologically active molecules and its diversified nature makes it a versatile substrate for further modifications. It is concernedin many pharmacological activities like anti-malarial, antiviral, anti-allergic, antimicrobial etc; isatin and its derivatives have been also found todemonstrate promising outcomes against various cancer cell lines. This review provides a brief overview on the recent advances and futureperspectives on chemistry and biological aspects of isatin and its derivatives reported in the recent past.

Recent Advances in Therapeutic Applications of Bisbenzimidazoles

2020 ◽  
Vol 16 (4) ◽  
pp. 454-486 ◽  
Author(s):  
Smita Verma ◽  
Vishnuvardh Ravichandiran ◽  
Nihar Ranjan ◽  
Swaran J.S. Flora
Keyword(s):  
Heterocyclic Compounds ◽  
Wide Spectrum ◽  
Dna Recognition ◽  
Present Review ◽  
Pharmacological Activities ◽  
Structural Motifs ◽  
Therapeutic Applications ◽  
The Past ◽  
Recent Advances

Nitrogen-containing heterocycles are one of the most common structural motifs in approximately 80% of the marketed drugs. Of these, benzimidazoles analogues are known to elicit a wide spectrum of pharmaceutical activities such as anticancer, antibacterial, antiparasitic, antiviral, antifungal as well as chemosensor effect. Based on the benzimidazole core fused heterocyclic compounds, crescent-shaped bisbenzimidazoles were developed which provided an early breakthrough in the sequence-specific DNA recognition. Over the years, a number of functional variations in the bisbenzimidazole core have led to the emergence of their unique properties and established them as versatile ligands against several classes of pathogens. The present review provides an overview of diverse pharmacological activities of the bisbenzimidazole analogues in the past decade with a brief account of its development through the years.

scholarly journals Recent advances in the chemical transformations of functionalized alkylidenecyclopropanes (FACPs)

2017 ◽  
Vol 53 (44) ◽  
pp. 5935-5945 ◽  
Author(s):  
Liu-Zhu Yu ◽  
Kai Chen ◽  
Zi-Zhong Zhu ◽  
Min Shi
Keyword(s):  
Heterocyclic Compounds ◽  
Chemical Transformations ◽  
Recent Advances

Classification of functionalized alkylidenecyclopropanes (FACPs) and recent chemical transformations for the synthesis of novel and useful polycyclic and heterocyclic compounds.

Nanomaterial-based biosensors using dual transducing elements for solution phase detection

The Analyst ◽  
2015 ◽  
Vol 140 (9) ◽  
pp. 2916-2943 ◽  
Author(s):  
Ning Li ◽  
Xiaodi Su ◽  
Yi Lu
Keyword(s):  
Design Principles ◽  
Solution Phase ◽  
Phase Detection ◽  
Recent Advances

This review describes the design principles of dual-transducer nanosensors and the recent advances in this field (“T” = target; “Trans.” in CL = Transducer).

scholarly journals Two decades of recent advances of Ugi reactions: synthetic and pharmaceutical applications

RSC Advances ◽  
2020 ◽  
Vol 10 (70) ◽  
pp. 42644-42681
Author(s):  
Manar Ahmed Fouad ◽  
Hamida Abdel-Hamid ◽  
Mohammed Salah Ayoup
Keyword(s):  
Natural Products ◽  
Heterocyclic Compounds ◽  
Cyclic Peptides ◽  
Ugi Reaction ◽  
Pharmaceutical Applications ◽  
Recent Advances

We highlight the recent advances of the Ugi reaction in the last two decades from 2000–2019, mainly in the synthesis of linear or cyclic peptides, heterocyclic compounds with versatile ring sizes, and natural products, as well as the enantioselective Ugi reactions.

Recent Advances of the Application of Organoiodine(Ⅲ) Reagents in the Construction of Heterocyclic Compounds

2016 ◽  
Vol 36 (11) ◽  
pp. 2513 ◽  
Author(s):  
Xiang Zhang ◽  
Ying Cong ◽  
Guangyu Lin ◽  
Xuliang Guo ◽  
Yang Cao ◽  
...  
Keyword(s):  
Heterocyclic Compounds ◽  
Recent Advances
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