Selective Phenolic Acylation of 10-Hydroxycamptothecin Using Poly (Ethylene Glycol) Carboxylic Acid.

ChemInform ◽  
2003 ◽  
Vol 34 (18) ◽  
Author(s):  
Richard B. Greenwald ◽  
Yun H. Choe ◽  
Dechun Wu
Keyword(s):  
Carboxylic Acid ◽  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Grafting modification of epoxidized natural rubber with poly(ethylene glycol) monomethylether carboxylic acid and ionic conductivity of graft polymer composite electrolytes

RSC Advances ◽  
2016 ◽  
Vol 6 (108) ◽  
pp. 107021-107028 ◽  
Author(s):  
Ran Wang ◽  
Hua Mei ◽  
Wentan Ren ◽  
Yong Zhang
Keyword(s):  
Carboxylic Acid ◽  
Ethylene Glycol ◽  
Natural Rubber ◽  
Epoxidized Natural Rubber ◽  
Graft Polymer ◽  
Composite Electrolytes ◽  
Poly Ethylene Glycol ◽  
Grafting Reaction ◽  
Grafting Modification ◽  
Poly Ethylene

A novel polymer was synthesized via a grafting reaction of epoxidized natural rubber (ENR) with poly(ethylene glycol) monomethylether carboxylic acid (mPEG-COOH), which can improve the conductivity as a matrix of CPE.

scholarly journals Solid-state mechanochemical ω-functionalization of poly(ethylene glycol)

2017 ◽  
Vol 13 ◽  
pp. 1963-1968 ◽  
Author(s):  
Michael Y Malca ◽  
Pierre-Olivier Ferko ◽  
Tomislav Friščić ◽  
Audrey Moores
Keyword(s):  
Solid State ◽  
Carboxylic Acid ◽  
Ethylene Glycol ◽  
Small Molecule ◽  
Poly Ethylene Glycol ◽  
Chemical Manufacturing ◽  
Pharmacokinetic Profiles ◽  
Wide Range ◽  
Poly Ethylene ◽  
Peg Functionalization

Poly(ethylene glycol) (PEG) is a linear polymer with a wide range of applications in chemical manufacturing, drug development and nanotechnology. PEG derivatives are being increasingly used to covalently modify small molecule and peptide drugs, as well as bioactive nanomaterials in order to improve solubility in biological serum, reduce immunogenicity, and enhance pharmacokinetic profiles. Herein we present the development of mechanochemical procedures for PEG functionalization without the need for bulk solvents, offering a cleaner and more sustainable alternative to existing solution-based PEG procedures. The herein presented mechanochemical procedures enable rapid and solvent-free derivatization of PEG with tosyl, bromide, thiol, carboxylic acid or amine functionalities in good to quantitative yields and with no polymer chain oligomerization, proving the versatility of the method.

New and Simple Synthetic Method for Carboxylic Acid Functionalized Poly(ethylene glycol)

Synlett ◽  
2008 ◽  
Vol 2008 (8) ◽  
pp. 1230-1232 ◽  
Author(s):  
Miloš Sedlák ◽  
Pavel Drabina ◽  
Markéta Svobodová ◽  
Jiří Hanusek
Keyword(s):  
Carboxylic Acid ◽  
Ethylene Glycol ◽  
Synthetic Method ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Synthesis and Characterization of Carboxylic Acids Bearing Poly(ethylene glycol) Chains

Synlett ◽  
2017 ◽  
Vol 29 (05) ◽  
pp. 556-559 ◽  
Author(s):  
Tetsuaki Fujihara ◽  
Yasushi Tsuji ◽  
Motoi Satou ◽  
Jun Terao
Keyword(s):  
Carboxylic Acid ◽  
Ethylene Glycol ◽  
Carboxylic Acids ◽  
Aerobic Oxidation ◽  
Synthesis And Characterization ◽  
Poly Ethylene Glycol ◽  
Carboxylate Ligands ◽  
Poly Ethylene

Carboxylic acids 1a and 1b bearing three poly(ethylene glycol) (PEG) chains and carboxylic acid 1c bearing one PEG chain were designed and synthesized. The carboxylic acids 1a–c were fully characterized by NMR and ESI-HRMS analyses. In a Pd-catalyzed aerobic oxidation of 1-phenylethanol, 1a and 1b worked well as carboxylate ligands.

Ester Functional Epoxide Monomers for Random and Gradient Poly(ethylene glycol) Polyelectrolytes with Multiple Carboxylic Acid Moieties

2020 ◽  
Vol 53 (9) ◽  
pp. 3524-3534
Author(s):  
Olga Linker ◽  
Jan Blankenburg ◽  
Kamil Maciol ◽  
Matthias Bros ◽  
Holger Frey
Keyword(s):  
Carboxylic Acid ◽  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene
Sign in / Sign up

Export Citation Format

Share Document