ChemInform Abstract: Amino Acid Derived Intramolecular 1,3-Dipolar Cycloadditions that Form Bridged Medium Ring Systems with Diastereoselective Control.

ChemInform ◽  
2010 ◽  
Vol 33 (37) ◽  
pp. no-no
Author(s):  
Yanbin Liu ◽  
Amy Maden ◽  
William V. Murray
Keyword(s):  
Amino Acid ◽  
Ring Systems ◽  
Dipolar Cycloadditions ◽  
Medium Ring

Use of highly stereospecific 1,3-dipolar cycloadditions of cyclic nitrones with acetylenes in the preparation of novel heterocyclic ring systems

1997 ◽  
pp. 155-162 ◽  
Author(s):  
W. Russell Bowman ◽  
Roy V. Davies ◽  
Alexandra M. Z. Slawin ◽  
Gian S. Sohal ◽  
Roger B. Titman ◽  
...  
Keyword(s):  
Heterocyclic Ring ◽  
Ring Systems ◽  
Dipolar Cycloadditions ◽  
Cyclic Nitrones

Intramolecular 1,4-Dipolar Cycloadditions of Cross-Conjugated Heteroaromatic Betaines. Synthesis of Hexahydrojulolidines and Related Peri- and Ortho-Fused Ring Systems

1995 ◽  
Vol 60 (12) ◽  
pp. 3795-3805 ◽  
Author(s):  
Kevin T. Potts ◽  
Thevarak Rochanapruk ◽  
Albert Padwa ◽  
Steven J. Coats ◽  
Lazaros Hadjiarapoglou
Keyword(s):  
Ring Systems ◽  
Dipolar Cycloadditions ◽  
Fused Ring

Bioisosterically modified dipeptide excitatory amino acid receptor antagonists containing 3-oxygenated isothiazole ring systems

1997 ◽  
Vol 5 (8) ◽  
pp. 1569-1575 ◽  
Author(s):  
Lisa Matzen ◽  
Bjarke Ebert ◽  
Tine B. Stensbøl ◽  
Bente Frølund ◽  
Jerzy W. Jaroszewski ◽  
...  
Keyword(s):  
Amino Acid ◽  
Excitatory Amino Acid ◽  
Receptor Antagonists ◽  
Excitatory Amino Acid Receptor ◽  
Ring Systems ◽  
Acid Receptor

ChemInform Abstract: Cyclizations of Hydroxy Dithioketals. New Synthetic Technology for the Construction of Oxocenes and Related Medium-Ring Systems.

ChemInform ◽  
1989 ◽  
Vol 20 (43) ◽  
Author(s):  
K. C. NICOLAOU ◽  
C. V. C. PRASAD ◽  
C.-K. HWANG ◽  
M. E. DUGGAN ◽  
C. A. VEALE
Keyword(s):  
Ring Systems ◽  
Medium Ring

1,3-dipolar cycloadditions. Part XII - selective cycloaddition route to 4-nitroisoxazolidine ring systems

2007 ◽  
Vol 44 (5) ◽  
pp. 1045-1049 ◽  
Author(s):  
Avijit Banerji ◽  
Maya Gupta ◽  
Pizush Kanti Biswas ◽  
Thierry Prangé ◽  
Alain Neuman
Keyword(s):  
Ring Systems ◽  
Dipolar Cycloadditions

Synthesis of some 2,5-benzoxazocine and 2,6-benzoxazonine derivatives from ω-(Dihydroisoindol-2-yl)alkanol precursors by means of cyanogen bromide

1982 ◽  
Vol 35 (11) ◽  
pp. 2307 ◽  
Author(s):  
JB Bremner ◽  
N Thirasasana
Keyword(s):  
Cyanogen Bromide ◽  
Ring Systems ◽  
Derivatives Of ◽  
Medium Ring ◽  
Moderate Yield

Reaction of cyanogen bromide with 2-(1-phenyl-2,3-dihydro-1H-isoindol-2-yl)ethanol (5a) gave 1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine-5-carbonitrile (6a) in a low to moderate yield. Similarly, 3-(1-phenyl-2,3-dihydro-1H-isoindol-2-yl)propan-1-ol (5c) gave 1-phenyl-1,3,4,5,6,7-hexa-hydro-2,6-benzoxazonine-6-carbonitrile (6c). The analogous 1-(4-methoxyphenyl) derivatives of both medium ring systems were also prepared, and some mechanistic aspects of the results are discussed. Conversion of (6a) into the analgesic, Nefopam,is described.

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