ChemInform Abstract: A Rapid and Efficient One-Pot Synthesis of Substituted 2-(5H)-Furanones under Focused Microwave Irradiations.

ChemInform ◽  
2000 ◽  
Vol 31 (38) ◽  
pp. no-no
Author(s):  
Liang Liao ◽  
Didier Villemin
Keyword(s):  
One Pot ◽  
One Pot Synthesis ◽  
Microwave Irradiations

scholarly journals Iodine mediated one-pot synthesis of 3-cyano and 3-cyano-4-methylcoumarins

2014 ◽  
Vol 79 (5) ◽  
pp. 527-531 ◽  
Author(s):  
Dinesh Sharma ◽  
Jagdish Makrandi
Keyword(s):  
Thermal Conditions ◽  
Thermal Heating ◽  
One Pot ◽  
One Pot Synthesis ◽  
Microwave Irradiations ◽  
One Step

2-Hydroxybenzaldehydes 1a-e on reaction with malononitrile 2 in the presence of iodine as catalyst give 3-cyanocoumarins 3a-e in one step under thermal heating as well as microwave irradiations. The latter conditions are much more efficient in terms of time (2-5 minutes) and yield as compared to thermal conditions (2-2.5 hours). Following similar procedure, 3-cyano-4-methylcoumarins 3f-i have also been prepared by the reaction of 2-hydroxyacetophenones 1f-i with malononitrile 2.

A Rapid and Efficient One-Pot Synthesis of Substituted 2-(5H)-furanones under focused microwave irradiations

2000 ◽  
Vol 2000 (4) ◽  
pp. 179-181 ◽  
Author(s):  
Liang Liao ◽  
Didier Villemin
Keyword(s):  
Sodium Ethoxide ◽  
One Pot ◽  
One Pot Synthesis ◽  
Microwave Irradiations

3-Hydroxy-3-methyl-2-butanone 1 reacted with ethyl cyanocetate in 2 in the presence of sodium ethoxide under focused microwave irradiations to afford 3-cyano-4,5,5-trimethyl-2-( 5H)-furanone 3. Furanone 3 then condensed with aromatic or heteroaromatic aldehydes 4a–h to produce 3-cyano-4-( trans-aryl-vinyl)-5,5-dimethyl-2-( 5H)-furanones 5a–h in high overall yields (71–88%).

One-Pot Synthesis and Conformational Analysis of 6-Membered Cyclic Iodonium Salts

2020 ◽  
Author(s):  
Lucien Caspers ◽  
Julian Spils ◽  
Mattis Damrath ◽  
Enno Lork ◽  
Boris Nachtsheim
Keyword(s):  
Conformational Analysis ◽  
Bronsted Acids ◽  
One Pot ◽  
Benzyl Alcohols ◽  
Iodonium Salts ◽  
Efficient Approach ◽  
One Pot Synthesis ◽  
Diaryliodonium Salts

In this article we describe an efficient approach for the synthesis of cyclic diaryliodonium salts. The method is based on benzyl alcohols as starting materials and consists of an Friedel-Crafts-arylation/oxidation sequence. Besides a deep optimization, particluar focusing on the choice and ratios of the utilized Bronsted-acids and oxidants, we explore the substrate scope of this transformation. We also discuss an interesting isomerism of cyclic iodonium salts substituted with aliphatic substituents at the bridge head carbon. <br>

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