Regiospecific one-pot synthesis of pyrimido[4,5-d]pyrimidine derivatives in the solid state under microwave irradiations

2006 ◽  
Vol 16 (13) ◽  
pp. 3537-3540 ◽  
Author(s):  
Dipak Prajapati ◽  
Mukut Gohain ◽  
Ashim J. Thakur
2017 ◽  
Vol 19 (7) ◽  
pp. 1626-1629 ◽  
Author(s):  
Dumitru Sirbu ◽  
Andrew C. Benniston ◽  
Anthony Harriman

ChemInform ◽  
2005 ◽  
Vol 36 (49) ◽  
Author(s):  
Xiang-Shan Wang ◽  
Zhao-Sen Zeng ◽  
Da-Qing Shi ◽  
Shu-Jiang Tu ◽  
Xian-Yong Wei ◽  
...  

Nano Energy ◽  
2017 ◽  
Vol 35 ◽  
pp. 138-145 ◽  
Author(s):  
Huan Pang ◽  
Xinran Li ◽  
Qunxing Zhao ◽  
Huaiguo Xue ◽  
Wen-Yong Lai ◽  
...  

Synthesis ◽  
2018 ◽  
Vol 51 (02) ◽  
pp. 530-537 ◽  
Author(s):  
Moisés Romero-Ortega ◽  
Michelle Trujillo-Lagunas ◽  
Ignacio Medina-Mercado ◽  
Ivann Zaragoza-Galicia ◽  
Horacio Olivo

A convenient two-step, one-pot synthesis of 4-chloro-2-(trichloromethyl)pyrimidines starting from 2-(trichloromethyl)-1,3-diazabutadienes is described. These nitrogen heterocycles were prepared by a sequential acylation/intramolecular cyclization reaction between 2-(trichloromethyl)-1,3-diazabutadienes and acyl chlorides in the presence of triethylamine followed by treatment with POCl3. This is the first report for the synthesis of this type of 4-chloro-2-(trichloromethyl)pyrimidine derivatives and serves as a source for a wide variety of other substituted pyrimidines by nucleophilic substitution reactions.


Heterocycles ◽  
2017 ◽  
Vol 94 (1) ◽  
pp. 140 ◽  
Author(s):  
Kazuhiro Kobayashi ◽  
Daiki Fujiwara ◽  
Yuuho Shigemura ◽  
Hidetaka Hiyoshi ◽  
Kazuto Umezu

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