ChemInform Abstract: New β-Diketone and 3,5-Dimethyl Isoxazole Derivatives of Theophylline as Potential Bronchodilator Agents.

ChemInform ◽  
2010 ◽  
Vol 29 (39) ◽  
pp. no-no
Author(s):  
H. AKGUEN ◽  
A. BALKAN ◽  
K. EROL ◽  
O. S. BATU
Keyword(s):  
Bronchodilator Agents ◽  
Derivatives Of ◽  
Isoxazole Derivatives

Discovery of novel simplified isoxazole derivatives of sampangine as potent anti-cryptococcal agents

2019 ◽  
Vol 27 (5) ◽  
pp. 832-840 ◽  
Author(s):  
Zhuang Li ◽  
Na Liu ◽  
Jie Tu ◽  
Changjin Ji ◽  
Guiyan Han ◽  
...  
Keyword(s):  
Derivatives Of ◽  
Isoxazole Derivatives

scholarly journals Synthesis and antibacterial activity of triazole and isoxazole derivatives of ampicillin.

1983 ◽  
Vol 36 (11) ◽  
pp. 1516-1524 ◽  
Author(s):  
NAOHIKO YASUDA ◽  
HISAO IWAGAMI ◽  
YUKIO SASAKI
Keyword(s):  
Antibacterial Activity ◽  
Derivatives Of ◽  
Isoxazole Derivatives

Isoxazole derivatives of 6-fluoro-N-(6-methoxybenzo[d]thiazol-2-yl)benzo[d]thiazol-2-amine and N-(pyrimidin-2-yl)benzo[d]thiazol-2-amine: regulation of cell cycle and apoptosis by p53 activation via mitochondrial-dependent pathways

MedChemComm ◽  
2014 ◽  
Vol 5 (11) ◽  
pp. 1744-1750 ◽  
Author(s):  
Ravindra M. Kumbhare ◽  
Tulshiram L. Dadmal ◽  
T. Anjana Devi ◽  
Dinesh Kumar ◽  
Umesh B. Kosurkar ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Dna Damage ◽  
P53 Activation ◽  
Regulation Of Cell Cycle ◽  
Derivatives Of ◽  
Isoxazole Derivatives

The compounds depicted were shown to induce DNA damage and activate p53, which in turn activates Bax and decreases Bcl2 levels. This resulted in apoptosis in Colo205 cells.

scholarly journals Chalcone Ditosylates as Potent Precursor for Synthesis of Some 4,5-Disubstituted Isoxazoles with Antioxidant and Anti-inflammatory Activities

2019 ◽  
Vol 31 (8) ◽  
pp. 1847-1850
Author(s):  
Pragi ◽  
Jagdeep Singh Dua ◽  
Jitender Singh
Keyword(s):  
Antioxidant Properties ◽  
Hydroxylamine Hydrochloride ◽  
Anti Inflammatory ◽  
Derivatives Of ◽  
Isoxazole Derivatives

The present work emphasizes on the synthesis of a series of 4,5-disubstituted isoxazole derivatives of α,β-chalcone ditosylates which were synthesized by the reaction of α,β-chalcone ditosylates with hydroxylamine hydrochloride. Various α,β-chalcone ditosylates were prepared by the reaction of respective chalcones with hydroxyl (tosyloxy)iodobenzene.The synthesized compounds were characterized and subsequently evaluated for anti-inflammatory and antioxidant properties.

Synthesis of isoxazole derivatives of 4,5-dihydro-1H-pyrazole

2017 ◽  
Vol 53 (11) ◽  
pp. 1664-1668 ◽  
Author(s):  
A. A. Golovanov ◽  
I. S. Odin ◽  
A. V. Vologzhanina ◽  
E. D. Voronova ◽  
O. S. Anoshina ◽  
...  
Keyword(s):  
Derivatives Of ◽  
Isoxazole Derivatives

Isoxazole derivatives of silatrane: synthesis, characterization, in silico ADME profile, prediction of potential pharmacological activity and evaluation of antimicrobial action

2020 ◽  
Vol 34 (12) ◽  
Author(s):  
Sergey N. Adamovich ◽  
Evgeniy V. Kondrashov ◽  
Igor A. Ushakov ◽  
Nina S. Shatokhina ◽  
Elizaveta N. Oborina ◽  
...  
Keyword(s):  
Pharmacological Activity ◽  
In Silico ◽  
Antimicrobial Action ◽  
Adme Profile ◽  
Derivatives Of ◽  
Isoxazole Derivatives
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