ChemInform Abstract: Bioactive Constituents of Chinese Natural Medicines. Part 4. Rhodiolae Radix. Part 2. On the Histamine Release Inhibitors from the Underground Part of Rhodiola sacra (PRAIN ex HAMET) S. H. Fu (Crassulaceae): Chemical Structures of Rho

ChemInform ◽  
2010 ◽  
Vol 29 (7) ◽  
pp. no-no
Author(s):  
M. YOSHIKAWA ◽  
H. SHIMADA ◽  
S. HORIKAWA ◽  
T. MURAKAMI ◽  
H. SHIMODA ◽  
...  
Keyword(s):  
Histamine Release ◽  
Bioactive Constituents ◽  
Underground Part ◽  
Chemical Structures ◽  
Natural Medicines

scholarly journals Influencing Factors on the Physicochemical Characteristics of Tea Polysaccharides

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3457
Author(s):  
Ting Hu ◽  
Peng Wu ◽  
Jianfeng Zhan ◽  
Weixin Wang ◽  
Junfeng Shen ◽  
...  
Keyword(s):  
Influencing Factors ◽  
Biological Activities ◽  
Structural Difference ◽  
Physicochemical Characteristics ◽  
Bioactive Constituents ◽  
Preparation Methods ◽  
Processing Technologies ◽  
Chemical Structures ◽  
Tea Polysaccharides ◽  
Fine Structures

Tea polysaccharides (TPSs) are one of the main bioactive constituents of tea with various biological activities such as hypoglycemic effect, antioxidant, antitumor, and immunomodulatory. The bioactivities of TPSs are directly associated with their structures such as chemical composition, molecular weight, glycosidic linkages, and conformation among others. To study the relationship between the structures of TPSs and their bioactivities, it is essential to elucidate the structure of TPSs, particularly the fine structures. Due to the vast variation nature of monosaccharide units and their connections, the structure of TPSs is extremely complex, which is also affected by several major factors including tea species, processing technologies of tea and isolation methods of TPSs. As a result of the complexity, there are few studies on their fine structures and chain conformation. In the present review, we aim to provide a detailed summary of the multiple factors influencing the characteristics of TPS chemical structures such as variations of tea species, degree of fermentation, and preparation methods among others as well as their applications. The main aspects of understanding the structural difference of TPSs and influencing factors are to assist the study of the structure and bioactivity relationship and ultimately, to control the production of the targeted TPSs with the most desired biological activity.

scholarly journals Medicinal Foodstuffs. VI. Histamine Release Inhibitors from Kidney Bean, the Seeds of Phaseolus vulgaris L.: Chemical Structures of Sandosaponins A and B.

1997 ◽  
Vol 45 (5) ◽  
pp. 877-882 ◽  
Author(s):  
Masayuki YOSHIKAWA ◽  
Hiromi SHIMADA ◽  
Hajime KOMATSU ◽  
Tetsuo SAKURAMA ◽  
Norihisa NISHIDA ◽  
...  
Keyword(s):  
Phaseolus Vulgaris ◽  
Histamine Release ◽  
Kidney Bean ◽  
Phaseolus Vulgaris L ◽  
Chemical Structures

scholarly journals Chemical Constituents of the Root of Angelica tenuissima and their Anti-allergic Inflammatory Activity

2017 ◽  
Vol 12 (5) ◽  
pp. 1934578X1701200 ◽  
Author(s):  
Hyun Gyu Choi ◽  
In-Gyu Je ◽  
Geum Jin Kim ◽  
Joo-Won Nam ◽  
Sang Hee Shim ◽  
...  
Keyword(s):  
Mast Cells ◽  
Histamine Release ◽  
Methanolic Extract ◽  
Chemical Constituents ◽  
Inflammatory Activity ◽  
Plant Source ◽  
Chemical Structures ◽  
Human Mast Cells ◽  
Reported Data ◽  
First Time

A phthalide, levistolide A (1), and six coumarins, demethylsuberosin (2), fraxetin (3), (-)-marmesinin (4), 3'( S)- O-β-D-glucopyranosyl-3’,4'-dihydroxanthyletin (5), 3'( R)- O-β-D-glucopyranosyl-3’,4'-dihydroxanthyletin (6), and isopraeroside IV (7) were isolated from the methanolic extract of the roots of Angelica tenuissima Nakai. Their chemical structures were confirmed by comparing spectroscopic and reported data. All seven compounds were isolated for the first time from this plant source. The anti-allergic activities of compounds 1-7 were examined using human mast cells, and compounds 1-3 at 10 μM potently suppressed IL-6 expression and inhibited histamine release from human mast cells by more than 30%.

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