ChemInform Abstract: The Design and Synthesis of Orally Active Short Duration Spiroindane Growth Hormone Secretagogues.

ChemInform ◽  
2010 ◽  
Vol 29 (1) ◽  
pp. no-no
Author(s):  
J. R. TATA ◽  
ET AL. ET AL.
Keyword(s):  
Growth Hormone ◽  
Short Duration ◽  
Growth Hormone Secretagogues ◽  
Design And Synthesis ◽  
Orally Active

The design and synthesis of orally active short duration spiroindane growth hormone secretagogues

1997 ◽  
Vol 7 (17) ◽  
pp. 2319-2324 ◽  
Author(s):  
James R. Tata ◽  
Zhijian Lu ◽  
Thomas M. Jacks ◽  
Klaus D. Schleim ◽  
Kang Cheng ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Short Duration ◽  
Growth Hormone Secretagogues ◽  
Design And Synthesis ◽  
Orally Active

Substituted Bridged Phenyl Piperidines: Orally Active Growth Hormone Secretagogues.

ChemInform ◽  
2003 ◽  
Vol 34 (38) ◽  
Author(s):  
Zhijian Lu ◽  
James R. Tata ◽  
Kang Cheng ◽  
Liente Wei ◽  
Wanda W.-S. Chan ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Secretagogues ◽  
Active Growth ◽  
Orally Active

Design and Synthesis of Potent Macrocyclic Benzolactam Growth Hormone Secretagogues

1997 ◽  
Vol 80 (4) ◽  
pp. 1244-1259 ◽  
Author(s):  
Robert J. De Vita ◽  
Alison J. Frontier ◽  
William R. Schoen ◽  
Matthew J. Wyvratt ◽  
Michael H. Fisher ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Secretagogues ◽  
Design And Synthesis

Novel Orally Active Growth Hormone Secretagogues

1998 ◽  
Vol 41 (19) ◽  
pp. 3705-3714 ◽  
Author(s):  
Thomas K. Hansen ◽  
Michael Ankersen ◽  
Birgit S. Hansen ◽  
Kirsten Raun ◽  
Karin K. Nielsen ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Secretagogues ◽  
Active Growth ◽  
Orally Active

scholarly journals The synthesis of a small library of prospective growth hormone secretagogues

1999 ◽  
Vol 64 (10) ◽  
pp. 571-576
Author(s):  
Vojislav Pejovic ◽  
Vukic Soskic ◽  
Jelena Joksimovic
Keyword(s):  
Amino Acids ◽  
Growth Hormone ◽  
Combinatorial Chemistry ◽  
Methodological Approach ◽  
Rabbit Antiserum ◽  
Building Blocks ◽  
Growth Hormone Secretagogues ◽  
Growth Hormone Secretagogue ◽  
Design And Synthesis ◽  
Polyclonal Rabbit Antiserum

Employing tools of combinatorial chemistry, an original methodological approach has been developed and applied for the design and synthesis of a small library of peptide-like compounds, prospective growth hormone (GH) secretagogues. For this purpose seven building blocks of tBoc- and Fmoc-protected amino acids was used. In this way, a small, tripeptoid library on polyethylene glycolmonomethyl ether 5000 (PEG 5000) as a soluble support was obtained. The library was screened by a new, simple system, based on polyclonal rabbit antiserum raised against "GH secretagogue pharmacophore" of a known growth hormone secretagogue GHRP-6 (Hexarelin?) and the most promising GH secretagogue candidate was selected.

Oxindole Derivatives as Orally Active Potent Growth Hormone Secretagogues

2001 ◽  
Vol 44 (26) ◽  
pp. 4641-4649 ◽  
Author(s):  
Teruhisa Tokunaga ◽  
W. Ewan Hume ◽  
Takashi Umezome ◽  
Kazuhiko Okazaki ◽  
Yasuyuki Ueki ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Secretagogues ◽  
Potent Growth ◽  
Orally Active

Thiazole-derived potent, highly bioavailable short duration growth hormone secretagogues

1999 ◽  
Vol 9 (13) ◽  
pp. 1761-1766 ◽  
Author(s):  
Lihu Yang ◽  
Greg Morriello ◽  
Kwan Leung ◽  
Tom Jacks ◽  
Kang Cheng ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Short Duration ◽  
Growth Hormone Secretagogues
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