ChemInform Abstract: Acyclic Diastereoselective Synthesis Using Functionalized Thiazoles. Routes to Carbohydrates and Related Natural Products

ChemInform ◽  
2010 ◽  
Vol 23 (34) ◽  
pp. no-no
Author(s):  
A. DONDONI
Keyword(s):  
Natural Products ◽  
Diastereoselective Synthesis

scholarly journals Lewis Acid Mediated Cyclizations: Diastereoselective Synthesis of Six- to Eight-Membered Substituted Cyclic Ethers

Synthesis ◽  
2017 ◽  
Vol 49 (18) ◽  
pp. 4229-4246 ◽  
Author(s):  
Arun Ghosh ◽  
Anthony Tomaine ◽  
Kelsey Cantwell
Keyword(s):  
Natural Products ◽  
Drug Design ◽  
Lewis Acid ◽  
Medicinal Chemistry ◽  
Cyclic Ether ◽  
Cyclic Ethers ◽  
Diastereoselective Synthesis ◽  
Acid Catalyzed

Cyclic ethers are widely abundant in natural products. Cyclic ether templates are also utilized in drug design and medicinal chemistry. Although the synthetic processes for this class of compounds have been studied extensively with respect to five- and six-membered rings, medium-sized cyclic ethers are synthetically more challenging due to a variety of factors. Herein, we report our results on the Lewis acid catalyzed synthesis of medium-sized cyclic ethers in a diastereoselective manner.

scholarly journals New Advances in the Synthetic Application of Enantiomeric 1-Phenylethylamine (α-PEA): Privileged Chiral Inducer and Auxiliary

Molecules ◽  
2020 ◽  
Vol 25 (21) ◽  
pp. 4907
Author(s):  
Marzena Wosińska-Hrydczuk ◽  
Jacek Skarżewski
Keyword(s):  
Natural Products ◽  
Chiral Auxiliary ◽  
Asymmetric Reactions ◽  
Chiral Resolution ◽  
Chiral Ligands ◽  
Diastereoselective Synthesis ◽  
New Developments ◽  
Synthetic Reactions ◽  
Medicinal Substances ◽  
Synthetic Application

New developments in the synthesis, resolution, and synthetic applications of chiral 1-phenylethylamine (α-PEA) reported in the last decade have been reviewed. In particular, improvements in the synthesis of α-PEA and its derivatives and chiral resolution, as well as their applications in the resolution of other compounds, were discussed. α-PEA was used as a chiral auxiliary in the diastereoselective synthesis of medicinal substances and natural products. Chiral ligands with α-PEA moieties were applied in asymmetric reactions, and effective modular chiral organocatalysts were constructed with α-PEA fragments and used in important synthetic reactions.

ChemInform Abstract: New Developments in Diastereoselective Synthesis of Drugs Derived from Natural Products

ChemInform ◽  
1989 ◽  
Vol 20 (17) ◽  
Author(s):  
W. BARTMANN ◽  
G. BECK ◽  
R. GEIGER ◽  
R. HENNING ◽  
V. TEETZ ◽  
...  
Keyword(s):  
Natural Products ◽  
Diastereoselective Synthesis ◽  
New Developments

scholarly journals Diastereoselective synthesis and biological evaluation of enantiomerically pure tricyclic indolines

2017 ◽  
Vol 15 (19) ◽  
pp. 4241-4245 ◽  
Author(s):  
W. He ◽  
B. M. Griffiths ◽  
W. Wang ◽  
X. Wang
Keyword(s):  
Natural Products ◽  
Biological Evaluation ◽  
Diastereoselective Synthesis ◽  
Chemical Probes ◽  
Enantiomerically Pure ◽  
Synthesis And Biological Evaluation

Tricyclic indolines are common in both natural products and synthetic chemical probes.

Sign in / Sign up

Export Citation Format

Share Document