ChemInform Abstract: REARRANGEMENT REACTIONS OF HETEROCYCLES, PART 5. THE REACTION OF 4-HYDROXY-2-QUINOLONE WITH REACTIVE MALONIC ACID DERIVATIVES

1976 ◽  
Vol 7 (46) ◽  
pp. no-no
Author(s):  
G. NOEHAMMER ◽  
T. KAPPE
Keyword(s):  
Malonic Acid ◽  
Malonic Acid Derivatives ◽  
Rearrangement Reactions

3-(s-Hydrindacen-4-yl)propylamines and 4-(s-hydrindacen-4-yl)butylamines; Synthesis and pharmacological screening

1981 ◽  
Vol 46 (8) ◽  
pp. 1800-1807 ◽  
Author(s):  
Zdeněk Vejdělek ◽  
Marie Bartošová ◽  
Miroslav Protiva
Keyword(s):  
Malonic Acid ◽  
Local Anaesthetics ◽  
Lithium Aluminium Hydride ◽  
Spasmolytic Activity ◽  
Lithium Aluminium ◽  
Malonic Acid Derivatives ◽  
Pharmacological Screening ◽  
Hydroxyethyl Piperazine

4-Chloromethyl-s-hydrindacene (VIIa) was transformed via the malonic acid derivatives VIIIa and IXa to the acid Xb which afforded in four steps the homological acid Xc. Reactions of chlorides of both acids (XIbc ) with dimethylamine, 1-methylpiperazine and 1-(2-hydroxyethyl)piperazine led to the amides XIIbc-XIVbc which were reduced with lithium aluminium hydride to the title compounds IVcd-VIcd. The amines obtained show central neuroleptic effects only in subtoxic doses; they are also potent local anaesthetics and have significant spasmolytic activity of the neurotropic as well as musculotropic type.

ChemInform Abstract: Chromium-Carbene-Mediated Synthesis of 4-Oxo β-Lactams ( Malonimides) and Malonic Acid Derivatives.

ChemInform ◽  
2010 ◽  
Vol 23 (24) ◽  
pp. no-no
Author(s):  
B. ALCAIDE ◽  
G. DOMINGUEZ ◽  
J. PLUMET ◽  
M. A. SIERRA
Keyword(s):  
Malonic Acid ◽  
Malonic Acid Derivatives ◽  
Chromium Carbene

Microwave Heating in Organic Synthesis: Decarboxylation of Malonic Acid Derivatives in Water

2000 ◽  
Vol 30 (12) ◽  
pp. 2099-2104 ◽  
Author(s):  
Cynthia Lynn Zara ◽  
Thomas Jin ◽  
Raymond J. Giguere
Keyword(s):  
Microwave Heating ◽  
Organic Synthesis ◽  
Malonic Acid ◽  
Malonic Acid Derivatives

scholarly journals Solvent- and Catalyst-Free Microwave-Assisted Decarboxylation of Malonic Acid Derivatives

2017 ◽  
Vol 07 (04) ◽  
pp. 270-280 ◽  
Author(s):  
Fanny Araceli Cabrera-Rivera ◽  
Luis Gabriel Hernández-Vázquez ◽  
Patricia Flores-Sánchez ◽  
Maria Durán-Galván ◽  
Jaime Escalante
Keyword(s):  
Malonic Acid ◽  
Microwave Assisted ◽  
Catalyst Free ◽  
Malonic Acid Derivatives

Reaction with Nucleophiles Leading to Malonic Acid Derivatives

2006 ◽  
pp. 1
Author(s):  
W. F. Austin ◽  
J. J. Kowalczyk ◽  
G. B. Dudley ◽  
R. L. Danheiser
Keyword(s):  
Malonic Acid ◽  
Malonic Acid Derivatives

NBS/DBU-Promoted One-Pot Three-Component Cycloaddition of Malonic Acid Derivatives, Nitrosoarenes, and Alkenes: Synthesis of Isoxazolidines

2020 ◽  
Vol 86 (1) ◽  
pp. 1096-1107
Author(s):  
Xing Li ◽  
Leijie Zheng ◽  
Xiaolei Gong ◽  
Honghong Chang ◽  
Wenchao Gao ◽  
...  
Keyword(s):  
Malonic Acid ◽  
One Pot ◽  
Malonic Acid Derivatives
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