Enhanced Fluorescence Turn-on Imaging of Hypochlorous Acid in Living Immune and Cancer Cells

2016 ◽  
Vol 22 (28) ◽  
pp. 9642-9648 ◽  
Author(s):  
Sandip V. Mulay ◽  
Minsuk Choi ◽  
Yoon Jeong Jang ◽  
Youngsam Kim ◽  
Sangyong Jon ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Hypochlorous Acid ◽  
Enhanced Fluorescence ◽  
Turn On ◽  
Fluorescence Turn On

A benzothiazole-based fluorescence turn-on sensor for copper(II)

2021 ◽  
Author(s):  
Gyeongjin Kim ◽  
Donghwan Choi ◽  
Cheal Kim
Keyword(s):  
Charge Transfer ◽  
Limit Of Detection ◽  
Theoretical Calculations ◽  
Enhanced Fluorescence ◽  
Turn On ◽  
Fluorescent Response ◽  
Chelation Enhanced Fluorescence ◽  
Fluorescence Turn On ◽  
Internal Charge Transfer ◽  
Internal Charge

Abstract A new benzothiazole-based chemosensor BTN (1-((Z)-(((E)-3-methylbenzo[d]thiazol-2(3H)-ylidene)hydrazono)methyl)naphthalen-2-ol) was synthesized for the detection of Cu2+. BTN could detect Cu2+ with “off-on” fluorescent response from colorless to yellow irrespective of presence of other cations. Limit of detection for Cu2+ was determined to be 3.3 µM. Binding ratio of BTN and Cu2+ turned out to be a 1:1 with the analysis of Job plot and ESI-MS. Sensing feature of Cu2+ by BTN was explained with theoretical calculations, which might be owing to internal charge transfer and chelation-enhanced fluorescence processes.

Cell-specific activation of gemcitabine by endogenous H2S stimulation and tracking through simultaneous fluorescence turn-on

2021 ◽  
Vol 57 (75) ◽  
pp. 9614-9617
Author(s):  
Mrinmoy Maiti ◽  
Shin A Yoon ◽  
Yujin Cha ◽  
K. K. Athul ◽  
Sankarprasad Bhuniya ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Anticancer Efficacy ◽  
Turn On ◽  
Fluorescence Turn On

The endogenous H2S stimulated theranostic H2S-Gem was developed for selectively ending the progression of cancer via activation of chemotherapeutic gemcitabine, which tracks theranostic events and provides anticancer efficacy against cancer cells.

Efficacious fluorescence turn-on probe for high-contrast imaging of human cells overexpressing quinone reductase activity

2017 ◽  
Vol 53 (4) ◽  
pp. 783-786 ◽  
Author(s):  
Quinn A. Best ◽  
Bijeta Prasai ◽  
Alexandra Rouillere ◽  
Amanda E. Johnson ◽  
Robin L. McCarley
Keyword(s):  
Cancer Cells ◽  
Reductase Activity ◽  
Quinone Reductase ◽  
High Contrast ◽  
Positive Signal ◽  
Contrast Imaging ◽  
Turn On ◽  
High Contrast Imaging ◽  
Fluorescence Images ◽  
Fluorescence Turn On

A turn-on substrate probe is activated by an oxidoreductase, offering fluorescence images of cancer cells with unprecedented positive signal-to-negative background ratios.

A novel quinolinyl-tetraphenylethene-based fluorescence “turn-on” sensor for Zn2+ with a large Stokes shift and its applications for portable test strips and biological imaging

2020 ◽  
Vol 4 (11) ◽  
pp. 3338-3348
Author(s):  
Jianxing Xu ◽  
Jingwen Xiong ◽  
Yanlin Qin ◽  
Zongzhi Li ◽  
Chengqiang Pan ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Stokes Shift ◽  
Biological Imaging ◽  
Enhanced Fluorescence ◽  
Test Strips ◽  
Large Stokes Shift ◽  
Turn On ◽  
Neutral Aqueous Solution ◽  
Chelation Enhanced Fluorescence ◽  
Fluorescence Turn On

A new 8-hydroxyquinoline derivative TPE(OH)-8HQ, has been synthesized and evaluated as an efficient fluorescence “turn-on” sensor for detection of Zn2+ based on the chelation-enhanced fluorescence (CHEF) mechanism in neutral aqueous solution.

Fluorescence turn-on detection of hypochlorous acid via HOCl-promoted dihydrofluorescein-ether oxidation and its application in vivo

2012 ◽  
Vol 48 (39) ◽  
pp. 4677 ◽  
Author(s):  
Yi Zhou ◽  
Ju-Ying Li ◽  
Kai-Hui Chu ◽  
Ke Liu ◽  
Cheng Yao ◽  
...  
Keyword(s):  
Hypochlorous Acid ◽  
Turn On ◽  
Fluorescence Turn On

A Boronic Acid-Based Fluorescence Hydrogel for Monosaccharide Detection

2018 ◽  
Author(s):  
Suying Xu ◽  
Adam Sedgwick ◽  
Souad Elfecky ◽  
Wenbo Chen ◽  
Ashley Jones ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Boronic Acid ◽  
Binding Constants ◽  
Strong Fluorescence ◽  
Fluorescence Response ◽  
Turn On ◽  
Fluorescence Turn On ◽  
Hydrogel System

<p>A boronic acid-based anthracene fluorescent probe was functionalised with an acrylamide unit to incorporate into a hydrogel system for monosaccharide detection<i>. </i>In solution, the fluorescent probe<b> </b>displayed a strong fluorescence turn-on response upon exposure to fructose, and an expected trend in apparent binding constants, as judged by a fluorescence response where D-fructose > D-galactose > D-mannose > D-glucose. The hydrogel incorporating the boronic acid monomer demonstrated the ability to detect monosaccharides by fluorescence with the same overall trend as the monomer in solution with the addition of fructose resulting in a 10-fold enhancement (≤ 0.25 M). <b><u></u></b></p>

Simple Fluorescence Turn-On Chemosensor for Selective Detection of Ba2+ Ion and Its Live Cell Imaging

2019 ◽  
Vol 91 (15) ◽  
pp. 10095-10101 ◽  
Author(s):  
Palanisamy Ravichandiran ◽  
Sivakumar Allur Subramaniyan ◽  
Antony Paulraj Bella ◽  
Princy Merlin Johnson ◽  
Ae Rhan Kim ◽  
...  
Keyword(s):  
Live Cell Imaging ◽  
Cell Imaging ◽  
Live Cell ◽  
Selective Detection ◽  
Turn On ◽  
Fluorescence Turn On
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