Efficacious fluorescence turn-on probe for high-contrast imaging of human cells overexpressing quinone reductase activity

2017 ◽  
Vol 53 (4) ◽  
pp. 783-786 ◽  
Author(s):  
Quinn A. Best ◽  
Bijeta Prasai ◽  
Alexandra Rouillere ◽  
Amanda E. Johnson ◽  
Robin L. McCarley
Keyword(s):  
Cancer Cells ◽  
Reductase Activity ◽  
Quinone Reductase ◽  
High Contrast ◽  
Positive Signal ◽  
Contrast Imaging ◽  
Turn On ◽  
High Contrast Imaging ◽  
Fluorescence Images ◽  
Fluorescence Turn On

A turn-on substrate probe is activated by an oxidoreductase, offering fluorescence images of cancer cells with unprecedented positive signal-to-negative background ratios.

Highly Luminescent-Paramagnetic Nanophosphor Probes for In Vitro High-Contrast Imaging of Human Breast Cancer Cells

Small ◽  
2012 ◽  
Vol 8 (19) ◽  
pp. 3028-3034 ◽  
Author(s):  
Bipin Kumar Gupta ◽  
Tharangattu N. Narayanan ◽  
Sajna Antony Vithayathil ◽  
Yean Lee ◽  
Shyny Koshy ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
High Contrast ◽  
Human Breast Cancer Cells ◽  
Human Breast ◽  
Contrast Imaging ◽  
High Contrast Imaging

Synthesis of two-photon active cinnamoyl coumarins for high-contrast imaging of cancer cells and their photophysical characterization

2014 ◽  
Vol 280 ◽  
pp. 39-45 ◽  
Author(s):  
Preeti Yadav ◽  
Soumitra Satapathi ◽  
Meena Kumari ◽  
Akanksha Chaturvedi ◽  
Lian Li ◽  
...  
Keyword(s):  
Cancer Cells ◽  
High Contrast ◽  
Contrast Imaging ◽  
Two Photon ◽  
High Contrast Imaging

The CM120 Biotwin: a high-contrast objective lens, optimum cryo-vacuum and improved EDX performance

1995 ◽  
Vol 53 ◽  
pp. 584-585
Author(s):  
Uwe Lücken ◽  
Michael Felsmann ◽  
Wim M. Busing ◽  
Frank de Jong
Keyword(s):  
Life Science ◽  
Focal Length ◽  
Objective Lens ◽  
High Contrast ◽  
Contrast Imaging ◽  
X Ray ◽  
Forming Mechanism ◽  
Similar Image ◽  
High Contrast Imaging ◽  
Low Concentrations

A new microscope for the study of life science specimen has been developed. Special attention has been given to the problems of unstained samples, cryo-specimens and x-ray analysis at low concentrations.A new objective lens with a Cs of 6.2 mm and a focal length of 5.9 mm for high-contrast imaging has been developed. The contrast of a TWIN lens (f = 2.8 mm, Cs = 2 mm) and the BioTWTN are compared at the level of mean and SD of slow scan CCD images. Figure 1a shows 500 +/- 150 and Fig. 1b only 500 +/- 40 counts/pixel. The contrast-forming mechanism for amplitude contrast is dependent on the wavelength, the objective aperture and the focal length. For similar image conditions (same voltage, same objective aperture) the BioTWIN shows more than double the contrast of the TWIN lens. For phasecontrast specimens (like thin frozen-hydrated films) the contrast at Scherzer focus is approximately proportional to the √ Cs.

scholarly journals Anti-quenching NIR-II molecular fluorophores for in vivo high-contrast imaging and pH sensing

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Shangfeng Wang ◽  
Yong Fan ◽  
Dandan Li ◽  
Caixia Sun ◽  
Zuhai Lei ◽  
...  
Keyword(s):  
Ph Sensing ◽  
High Contrast ◽  
Contrast Imaging ◽  
High Contrast Imaging

Simulations of exoplanets detection obtained with a high-contrast imaging instrument: CHEOPS

2004 ◽  
Author(s):  
Alessandro Berton ◽  
Raffaele G. Gratton ◽  
Markus Feldt ◽  
Silvano Desidera ◽  
Elena Masciadri ◽  
...  
Keyword(s):  
High Contrast ◽  
Contrast Imaging ◽  
High Contrast Imaging ◽  
Imaging Instrument

Laboratory test of a polarimetry imaging subtraction system for the high-contrast imaging

2012 ◽  
Author(s):  
Jiangpei Dou ◽  
Deqing Ren ◽  
Yongtian Zhu ◽  
Xi Zhang ◽  
Rong Li
Keyword(s):  
Laboratory Test ◽  
High Contrast ◽  
Contrast Imaging ◽  
High Contrast Imaging

Technological progress of a ferrofluid deformable mirror with tunable nominal optical power for high-contrast imaging

2015 ◽  
Author(s):  
Aaron J. Lemmer ◽  
Tyler D. Groff ◽  
N. Jeremy Kasdin ◽  
Daniel Echeverri ◽  
Isabel R. Cleff
Keyword(s):  
Technological Progress ◽  
Optical Power ◽  
Deformable Mirror ◽  
High Contrast ◽  
Contrast Imaging ◽  
High Contrast Imaging
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