scholarly journals Simultaneously Sizing and Quantitating Zeptomole-Level DNA at High Throughput in Free Solution

2014 ◽  
Vol 20 (43) ◽  
pp. 13821-13821
Author(s):  
Zaifang Zhu ◽  
Huang Chen ◽  
Apeng Chen ◽  
Joann J. Lu ◽  
Shaorong Liu ◽  
...  
Keyword(s):  
High Throughput ◽  
Free Solution

scholarly journals High-throughput cryo-EM enabled by user-free preprocessing routines

2019 ◽  
Author(s):  
Yilai Li ◽  
Jennifer N. Cash ◽  
John. J.G. Tesmer ◽  
Michael A. Cianfrocco
Keyword(s):  
Image Analysis ◽  
Deep Learning ◽  
Structural Biology ◽  
High Throughput ◽  
Data Preprocessing ◽  
Free Solution ◽  
Multiple Datasets ◽  
User Friendly ◽  
Collection Strategies ◽  
Automatic Pipeline

ABSTRACTThe growth of single-particle cryo-EM into a mainstream structural biology tool has allowed for many important biological discoveries. Continued developments in data collection strategies alongside new sample preparation devices heralds a future where users will collect multiple datasets per microscope session. To make cryo-EM data processing more automatic and user-friendly, we have developed an automatic pipeline for cryo-EM data preprocessing and assessment using a combination of deep learning and image analysis tools. We have verified the performance of this pipeline on a number of datasets and extended its scope to include sample screening by the user-free assessment of the qualities of a series of datasets under different conditions. We propose that our workflow provides a decision-free solution for cryo-EM, making data preprocessing more generalized and robust in the high-throughput era as well as more convenient for users from a range of backgrounds.

High-Throughput Single-Molecule Spectroscopy in Free Solution

2000 ◽  
Vol 72 (19) ◽  
pp. 4640-4645 ◽  
Author(s):  
Yinfa Ma ◽  
Michael R. Shortreed ◽  
Edward S. Yeung
Keyword(s):  
High Throughput ◽  
Single Molecule ◽  
Single Molecule Spectroscopy ◽  
Free Solution

scholarly journals Cover Picture: Simultaneously Sizing and Quantitating Zeptomole-Level DNA at High Throughput in Free Solution (Chem. Eur. J. 43/2014)

2014 ◽  
Vol 20 (43) ◽  
pp. 13817-13817
Author(s):  
Zaifang Zhu ◽  
Huang Chen ◽  
Apeng Chen ◽  
Joann J. Lu ◽  
Shaorong Liu ◽  
...  
Keyword(s):  
High Throughput ◽  
Free Solution

scholarly journals Simultaneously Sizing and Quantitating Zeptomole-Level DNA at High Throughput in Free Solution

2014 ◽  
Vol 20 (43) ◽  
pp. 13945-13950 ◽  
Author(s):  
Zaifang Zhu ◽  
Huang Chen ◽  
Apeng Chen ◽  
Joann J. Lu ◽  
Shaorong Liu ◽  
...  
Keyword(s):  
High Throughput ◽  
Free Solution

Multiplexed, High-Throughput Genotyping by Single-Base Extension and End-Labeled Free-Solution Electrophoresis

2002 ◽  
Vol 74 (17) ◽  
pp. 4328-4333 ◽  
Author(s):  
Wyatt N. Vreeland ◽  
Robert J. Meagher ◽  
Annelise E. Barron
Keyword(s):  
High Throughput ◽  
Free Solution ◽  
Single Base Extension ◽  
Single Base ◽  
Base Extension

154: Integration of TPSA and High-Throughput Mass Spectrometry Data Improves Prostate Cancer Prediction

2007 ◽  
Vol 177 (4S) ◽  
pp. 52-53
Author(s):  
Stefano Ongarello ◽  
Eberhard Steiner ◽  
Regina Achleitner ◽  
Isabel Feuerstein ◽  
Birgit Stenzel ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Mass Spectrometry ◽  
High Throughput ◽  
Mass Spectrometry Data ◽  
Cancer Prediction
Sign in / Sign up

Export Citation Format

Share Document