Benzofurazane as a New Redox Label for Electrochemical Detection of DNA: Towards Multipotential Redox Coding of DNA Bases

2013 ◽  
Vol 19 (38) ◽  
pp. 12720-12731 ◽  
Author(s):  
Jana Balintová ◽  
Medard Plucnara ◽  
Pavlína Vidláková ◽  
Radek Pohl ◽  
Luděk Havran ◽  
...  
Keyword(s):  
Electrochemical Detection ◽  
Dna Bases ◽  
Redox Label

scholarly journals Phenothiazine-linked nucleosides and nucleotides for redox labelling of DNA

2017 ◽  
Vol 15 (33) ◽  
pp. 6984-6996 ◽  
Author(s):  
Anna Simonova ◽  
Luděk Havran ◽  
Radek Pohl ◽  
Miroslav Fojta ◽  
Michal Hocek
Keyword(s):  
Electrochemical Detection ◽  
Enzymatic Synthesis ◽  
Dna Bases ◽  
Modified Nucleotides

New phenothiazine-modified nucleotides were prepared and used for enzymatic synthesis of labelled DNA for electrochemical detection and redox coding of DNA bases.

Highly sensitive electrochemical detection of DNA hybridisation by coupling the chemical reduction of a redox label to the electrode reaction of a solution phase mediator

The Analyst ◽  
2014 ◽  
Vol 139 (22) ◽  
pp. 5740-5746 ◽  
Author(s):  
Umphan Ngoensawat ◽  
Patsamon Rijiravanich ◽  
Mithran Somasundrum ◽  
Werasak Surareungchai
Keyword(s):  
Electrochemical Detection ◽  
Chemical Reduction ◽  
Electrode Reaction ◽  
Solution Phase ◽  
Stem Loop ◽  
Highly Sensitive ◽  
Dna Hybridisation ◽  
Redox Label ◽  
Sensitive Method

We have described a highly sensitive method for detecting DNA hybridisation using a redox-labeled stem loop probe.

scholarly journals Measurement of oxidized and methylated DNA bases by HPLC with electrochemical detection

1996 ◽  
Vol 318 (1) ◽  
pp. 21-23 ◽  
Author(s):  
Harparkash KAUR ◽  
Barry HALLIWELL
Keyword(s):  
Gene Expression ◽  
Dna Methylation ◽  
Dna Damage ◽  
Electrochemical Detection ◽  
Oxidative Dna Damage ◽  
The Other ◽  
Dna Bases ◽  
Cancer Development ◽  
Methylated Dna ◽  
Important Contributor

Oxidative DNA damage is thought to be an important contributor to cancer development and to be affected by dietary constituents, so its accurate measurement is important. DNA methylation is recognized as an important mechanism affecting gene expression. In the present paper we describe an HPLC-with-electrochemical-detection procedure that allows rapid and sensitive measurement of four oxidized (2,6-diamino-4-hydroxy-5-formamidopyrimidine, 5-hydroxyuracil, 8-hydroxyguanine, 8-hydroxyadenine) and three methylated (7-methylguanine, 1-methylguanine, O6-methylguanine) bases in acid hydrolysates of DNA. Guanine was also detected, but was clearly separated from the other bases.

Use of DNA Repair Enzymes in Electrochemical Detection of Damage to DNA Bases in Vitro and in Cells

2005 ◽  
Vol 77 (9) ◽  
pp. 2920-2927 ◽  
Author(s):  
Kateřina Cahová-Kuchaříková ◽  
Miroslav Fojta ◽  
Tomáš Mozga ◽  
Emil Paleček
Keyword(s):  
Dna Repair ◽  
Electrochemical Detection ◽  
Dna Bases ◽  
Dna Repair Enzymes ◽  
Repair Enzymes ◽  
In Cells

scholarly journals Azidophenyl as a click-transformable redox label of DNA suitable for electrochemical detection of DNA–protein interactions

2015 ◽  
Vol 6 (1) ◽  
pp. 575-587 ◽  
Author(s):  
Jana Balintová ◽  
Jan Špaček ◽  
Radek Pohl ◽  
Marie Brázdová ◽  
Luděk Havran ◽  
...  
Keyword(s):  
Electrochemical Detection ◽  
Protein Interactions ◽  
Click Reaction ◽  
Redox Label ◽  
Dna Protein Interactions

A new azido-based DNA redox label which can be transformed into nitrophenyltriazole by a CuAAC click reaction was developed. It was used for the mapping of DNA–protein interactions with electrochemical detection.

A copper-based metal–organic framework/graphene nanocomposite for the sensitive and stable electrochemical detection of DNA bases

The Analyst ◽  
2020 ◽  
Vol 145 (5) ◽  
pp. 1933-1942 ◽  
Author(s):  
Xiuyun Wang ◽  
Jie Zhang ◽  
Yuanan Wei ◽  
Tianyu Xing ◽  
Tingting Cao ◽  
...  
Keyword(s):  
Electrochemical Detection ◽  
Metal Organic Framework ◽  
Dna Bases ◽  
Electrode Modification ◽  
Metal Organic ◽  
Guanine And Adenine ◽  
Graphene Nanocomposite ◽  
Easy Operation ◽  
Organic Framework

A simple and easy-operation electrode modification strategy was proposed using Cu-MOF/GO nanohybrids for physiologists and pathologists for the feasible and reliable simultaneous electrochemical detections of DNA bases, namely guanine and adenine.

Sign in / Sign up

Export Citation Format

Share Document