The Synthesis of a New Class of Chiral Pincer Ligands and Their Applications in Enantioselective Catalytic Fluorinations and the Nozaki-Hiyama-Kishi Reaction

2011 ◽  
Vol 17 (52) ◽  
pp. 14922-14928 ◽  
Author(s):  
Qing-Hai Deng ◽  
Hubert Wadepohl ◽  
Lutz H. Gade
Keyword(s):  
Pincer Ligands ◽  
New Class

scholarly journals Diphosphinine Derivatives of Terpyridine: A New Class of Neutral π-Accepting PNP-Pincer Ligands

2008 ◽  
Vol 14 (29) ◽  
pp. 8803-8807 ◽  
Author(s):  
Christian Müller ◽  
Evgeny A. Pidko ◽  
Martin Lutz ◽  
Anthony L. Spek ◽  
Dieter Vogt
Keyword(s):  
Pincer Ligands ◽  
New Class ◽  
Derivatives Of

ChemInform Abstract: A New Class of PN3-Pincer Ligands for Metal-Ligand Cooperative Catalysis

ChemInform ◽  
2015 ◽  
Vol 46 (47) ◽  
pp. no-no
Author(s):  
Huaifeng Li ◽  
Bin Zheng ◽  
Kuo-Wei Huang
Keyword(s):  
Pincer Ligands ◽  
New Class ◽  
Cooperative Catalysis ◽  
Metal Ligand

scholarly journals A new class of PN3-pincer ligands for metal–ligand cooperative catalysis

2015 ◽  
Vol 293-294 ◽  
pp. 116-138 ◽  
Author(s):  
Huaifeng Li ◽  
Bin Zheng ◽  
Kuo-Wei Huang
Keyword(s):  
Pincer Ligands ◽  
New Class ◽  
Cooperative Catalysis ◽  
Metal Ligand

Synthesis of a new class of unsymmetrical PCP′ pincer ligands and their palladium (II) complexes: X-ray structure determination of PdCl{C6H3-2-CH2PPh2-6-CH2PBut2}

2004 ◽  
Vol 689 (15) ◽  
pp. 2494-2502 ◽  
Author(s):  
Ali Naghipour ◽  
Seyyed Javad Sabounchei ◽  
David Morales-Morales ◽  
Simón Hernández-Ortega ◽  
Craig M. Jensen
Keyword(s):  
Structure Determination ◽  
Pincer Ligands ◽  
X Ray ◽  
New Class ◽  
Pcp Pincer

Synthesis and coordination chemistry of new asymmetric donor/acceptor pincer ligands, 1,3-C6H4(CH2PtBu(Rf))2 (Rf = CF3, C2F5)

2018 ◽  
Vol 47 (35) ◽  
pp. 12420-12430
Author(s):  
Suman Debnath ◽  
Gabriel Venegas ◽  
Navamoney Arulsamy ◽  
Dean M. Roddick
Keyword(s):  
Coordination Chemistry ◽  
Pincer Ligands ◽  
New Class ◽  
Donor Acceptor

Syntheses of new asymmetric pincer precursors 1,3-C6H4{CH2P(tBu,X)}2 (tBu,XPCPH; X = Cl, SiMe3, OPh) and a new class of hybrid donor/acceptor pincer ligands 1,3-C6H4{CH2P(tBu,Rf)}2 (tBu,RfPCPH; Rf = CF3, C2F5) are reported.

scholarly journals Rhenium(I) Complexes with Pincer Ligands as a New Class of Potential Antitumor Agents

Proceedings ◽  
2019 ◽  
Vol 22 (1) ◽  
pp. 43
Author(s):  
Diana V. Aleksanyan ◽  
Svetlana G. Churusova ◽  
Ekaterina Yu. Rybalkina ◽  
Vladimir A. Kozlov
Keyword(s):  
Metal Complexes ◽  
Antitumor Agents ◽  
Solid Phase ◽  
Organometallic Compounds ◽  
Chemotherapeutic Agents ◽  
Palladium Complexes ◽  
Pincer Ligands ◽  
New Class ◽  
Solvent Free Conditions ◽  
Potential Antitumor

Transition metal complexes attract continuous research interest as potential antitumor agents. The most popular compounds are ruthenium, gold, titanium, osmium, iridium, zinc, and palladium complexes, which have already displayed cytotoxic features that are not typical for classical platinum-containing chemotherapeutic agents. Substantially lower attention is drawn to organometallic compounds of rhenium. However, the known examples of cytotoxic organometallic rhenium derivatives with bidentate heterocyclic, organophosphorus, labile alkoxide, and hydroxide ligands render further studies in this field very promising. As for their analogs with multidentate ligands, a literature survey has revealed only a few examples of cytotoxic rhenium complexes, whereas the antitumor activity of cyclometallated derivatives has not been studied at all. At the same time, it is known that the use of pincer-type ligands having specific tridentate monoanionic frameworks, which offer multiple options for directed structural modifications, allows one to finely tune the thermodynamic and kinetic stability of the resulting metal complexes. Therefore, we synthesized and studied the cytotoxic properties of a series of rhenium(I) complexes with tridentate pincer-type ligands based on functionalized carboxamides bearing ancillary donor groups both in the acid and amine components. It was shown that the target complexes can be obtained not only by the conventional solution-based method, but also under solvent-free conditions according to the solid-phase methodology recently developed in our group. The results obtained were used to define the main structure–activity relationships for a principally new class of potential antitumor agents and to choose the most promising compounds for further studies in order to create new pharmaceuticals.

In Situ microscopy of the anodic etching of silicon

1995 ◽  
Vol 53 ◽  
pp. 232-233
Author(s):  
Frances M. Ross ◽  
Peter C. Searson
Keyword(s):  
Composite Structures ◽  
High Surface ◽  
High Surface Area ◽  
Chemical Properties ◽  
Selective Etching ◽  
Silicon On Insulator ◽  
Second Phase ◽  
Porous Layers ◽  
New Class ◽  
Porous Semiconductors

Porous semiconductors represent a relatively new class of materials formed by the selective etching of a single or polycrystalline substrate. Although porous silicon has received considerable attention due to its novel optical properties1, porous layers can be formed in other semiconductors such as GaAs and GaP. These materials are characterised by very high surface area and by electrical, optical and chemical properties that may differ considerably from bulk. The properties depend on the pore morphology, which can be controlled by adjusting the processing conditions and the dopant concentration. A number of novel structures can be fabricated using selective etching. For example, self-supporting membranes can be made by growing pores through a wafer, films with modulated pore structure can be fabricated by varying the applied potential during growth, composite structures can be prepared by depositing a second phase into the pores and silicon-on-insulator structures can be formed by oxidising a buried porous layer. In all these applications the ability to grow nanostructures controllably is critical.

The microtubule associated protein (MAP) tau forms a new class of triple-stranded left-hand helical fibrous protein polymer

1992 ◽  
Vol 50 (1) ◽  
pp. 540-541
Author(s):  
G. C. Ruben ◽  
K. Iqbal ◽  
I. Grundke-Iqbal ◽  
H. Wisniewski ◽  
T. L. Ciardelli ◽  
...  
Keyword(s):  
Axial Ratio ◽  
Normal Structure ◽  
Paired Helical Filaments ◽  
Left Hand ◽  
New Class ◽  
Protein Polymer ◽  
Fibrous Protein ◽  
Protein Map ◽  
Neurotransmitter Transport ◽  
Alzheimer Neurofibrillary Tangles

In neurons, the microtubule associated protein, tau, is found in the axons. Tau stabilizes the microtubules required for neurotransmitter transport to the axonal terminal. Since tau has been found in both Alzheimer neurofibrillary tangles (NFT) and in paired helical filaments (PHF), the study of tau's normal structure had to preceed TEM studies of NFT and PHF. The structure of tau was first studied by ultracentrifugation. This work suggested that it was a rod shaped molecule with an axial ratio of 20:1. More recently, paraciystals of phosphorylated and nonphosphoiylated tau have been reported. Phosphorylated tau was 90-95 nm in length and 3-6 nm in diameter where as nonphosphorylated tau was 69-75 nm in length. A shorter length of 30 nm was reported for undamaged tau indicating that it is an extremely flexible molecule. Tau was also studied in relation to microtubules, and its length was found to be 56.1±14.1 nm.

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