Unique Self-Anhydride Formation in the Degradation of Cytidine-5′-monophosphosialic Acid (CMP-Neu5Ac) and Cytidine-5′-diphosphosialic Acid (CDP-Neu5Ac) and its Application in CMP-sialic Acid Analogue Synthesis

2011 ◽  
Vol 17 (27) ◽  
pp. 7645-7655 ◽  
Author(s):  
Yasuhiro Kajihara ◽  
Sachiko Nishigaki ◽  
Daisuke Hanzawa ◽  
Go Nakanishi ◽  
Ryo Okamoto ◽  
...  
Keyword(s):  
Sialic Acid ◽  
Acid Analogue ◽  
Sialic Acid Analogue

Total Biosynthesis of Legionaminic Acid, a Bacterial Sialic Acid Analogue

2016 ◽  
Vol 55 (39) ◽  
pp. 12018-12021 ◽  
Author(s):  
Mohamed I. Hassan ◽  
Benjamin R. Lundgren ◽  
Michael Chaumun ◽  
Dennis M. Whitfield ◽  
Brady Clark ◽  
...  
Keyword(s):  
Sialic Acid ◽  
Acid Analogue ◽  
Sialic Acid Analogue

Synthesis of the First Sialic Acid Analogue Containing a y-Pyrone Moiety

1999 ◽  
Vol 52 (12) ◽  
pp. 1127 ◽  
Author(s):  
Hua Chee Ooi ◽  
B Sebastian ◽  
M. Marcuccio ◽  
W. Roy Jackson ◽  
David F. O'Keefe
Keyword(s):  
Sialic Acid ◽  
Acid Derivative ◽  
Acetylneuraminic Acid ◽  
Acid Analogue ◽  
Sialic Acid Analogue

Oxidation of the two DANA (2-deoxy-2,3-didehydro-N-acetylneuraminic acid) derivatives (3) and (4) by using several reagents has led to the isolation of the first sialic acid derivative (1) containing a γ-pyrone moiety.

ChemInform Abstract: Synthesis of a Carbocyclic Sialic Acid Analogue for the Inhibition of Influenza Virus Neuraminidase.

ChemInform ◽  
2010 ◽  
Vol 32 (36) ◽  
pp. no-no
Author(s):  
Armandodoriano Bianco ◽  
Mario Brufani ◽  
Fedele Manna ◽  
Cristiana Melchioni
Keyword(s):  
Influenza Virus ◽  
Sialic Acid ◽  
Acid Analogue ◽  
Sialic Acid Analogue ◽  
Influenza Virus Neuraminidase

scholarly journals Bioorthogonal metabolic glycoengineering of human larynx carcinoma (HEp-2) cells targeting sialic acid

2010 ◽  
Vol 6 ◽  
Author(s):  
Arne Homann ◽  
Riaz-ul Qamar ◽  
Sevnur Serim ◽  
Petra Dersch ◽  
Jürgen Seibel
Keyword(s):  
Sialic Acid ◽  
Cell Surface ◽  
Carcinoma Cell ◽  
Larynx Carcinoma ◽  
Interaction Processes ◽  
Acid Analogue ◽  
Human Larynx ◽  
Sialic Acid Analogue ◽  
Metabolic Glycoengineering ◽  
Human Larynx Carcinoma

Sialic acids are located at the termini of mammalian cell-surface glycostructures, which participate in essential interaction processes including adhesion of pathogens prior to infection and immunogenicity. Here we present the synthesis and bioorthogonal metabolic incorporation of the sialic acid analogue N-(1-oxohex-5-ynyl)neuraminic acid (Neu5Hex) into the cell-surface glycocalyx of a human larynx carcinoma cell line (HEp-2) and its fluorescence labelling by click chemistry.

ChemInform Abstract: Synthesis of the First Sialic Acid Analogue Containing a γ-Pyrone Moiety.

ChemInform ◽  
2010 ◽  
Vol 31 (28) ◽  
pp. no-no
Author(s):  
Hua Chee Ooi ◽  
Sebastian M. Marcuccio ◽  
W. Roy Jackson ◽  
David F. O'Keefe
Keyword(s):  
Sialic Acid ◽  
Acid Analogue ◽  
Sialic Acid Analogue

Synthesis of a carbocyclic sialic acid analogue for the inhibition of influenza virus neuraminidase

2001 ◽  
Vol 332 (1) ◽  
pp. 23-31 ◽  
Author(s):  
Armandodoriano Bianco ◽  
Mario Brufani ◽  
Fedele Manna ◽  
Cristiana Melchioni
Keyword(s):  
Influenza Virus ◽  
Sialic Acid ◽  
Acid Analogue ◽  
Sialic Acid Analogue ◽  
Influenza Virus Neuraminidase

A convenient method for the introduction of nitrogen and sulfur at C-4 on a sialic acid analogue

1993 ◽  
Vol 244 (1) ◽  
pp. 181-185 ◽  
Author(s):  
Mark von Itzstein ◽  
Betty Jin ◽  
Wen-Yang Wu ◽  
Malcolm Chandler
Keyword(s):  
Sialic Acid ◽  
Convenient Method ◽  
Acid Analogue ◽  
Sialic Acid Analogue
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