ChemInform Abstract: Synthesis of a Carbocyclic Sialic Acid Analogue for the Inhibition of Influenza Virus Neuraminidase.

ChemInform ◽  
2010 ◽  
Vol 32 (36) ◽  
pp. no-no
Author(s):  
Armandodoriano Bianco ◽  
Mario Brufani ◽  
Fedele Manna ◽  
Cristiana Melchioni
Keyword(s):  
Influenza Virus ◽  
Sialic Acid ◽  
Acid Analogue ◽  
Sialic Acid Analogue ◽  
Influenza Virus Neuraminidase

Synthesis of a carbocyclic sialic acid analogue for the inhibition of influenza virus neuraminidase

2001 ◽  
Vol 332 (1) ◽  
pp. 23-31 ◽  
Author(s):  
Armandodoriano Bianco ◽  
Mario Brufani ◽  
Fedele Manna ◽  
Cristiana Melchioni
Keyword(s):  
Influenza Virus ◽  
Sialic Acid ◽  
Acid Analogue ◽  
Sialic Acid Analogue ◽  
Influenza Virus Neuraminidase

Total Biosynthesis of Legionaminic Acid, a Bacterial Sialic Acid Analogue

2016 ◽  
Vol 55 (39) ◽  
pp. 12018-12021 ◽  
Author(s):  
Mohamed I. Hassan ◽  
Benjamin R. Lundgren ◽  
Michael Chaumun ◽  
Dennis M. Whitfield ◽  
Brady Clark ◽  
...  
Keyword(s):  
Sialic Acid ◽  
Acid Analogue ◽  
Sialic Acid Analogue

A Secondary Sialic Acid Binding Site on Influenza Virus Neuraminidase: Fact or Fiction?

2012 ◽  
Vol 51 (9) ◽  
pp. 2221-2224 ◽  
Author(s):  
Jimmy C. C. Lai ◽  
Jean-Michel Garcia ◽  
Jeffrey C. Dyason ◽  
Raphael Böhm ◽  
Paul D. Madge ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Sialic Acid ◽  
Binding Site ◽  
Sialic Acid Binding ◽  
Influenza Virus Neuraminidase

Synthesis of the First Sialic Acid Analogue Containing a y-Pyrone Moiety

1999 ◽  
Vol 52 (12) ◽  
pp. 1127 ◽  
Author(s):  
Hua Chee Ooi ◽  
B Sebastian ◽  
M. Marcuccio ◽  
W. Roy Jackson ◽  
David F. O'Keefe
Keyword(s):  
Sialic Acid ◽  
Acid Derivative ◽  
Acetylneuraminic Acid ◽  
Acid Analogue ◽  
Sialic Acid Analogue

Oxidation of the two DANA (2-deoxy-2,3-didehydro-N-acetylneuraminic acid) derivatives (3) and (4) by using several reagents has led to the isolation of the first sialic acid derivative (1) containing a γ-pyrone moiety.

scholarly journals Bioorthogonal metabolic glycoengineering of human larynx carcinoma (HEp-2) cells targeting sialic acid

2010 ◽  
Vol 6 ◽  
Author(s):  
Arne Homann ◽  
Riaz-ul Qamar ◽  
Sevnur Serim ◽  
Petra Dersch ◽  
Jürgen Seibel
Keyword(s):  
Sialic Acid ◽  
Cell Surface ◽  
Carcinoma Cell ◽  
Larynx Carcinoma ◽  
Interaction Processes ◽  
Acid Analogue ◽  
Human Larynx ◽  
Sialic Acid Analogue ◽  
Metabolic Glycoengineering ◽  
Human Larynx Carcinoma

Sialic acids are located at the termini of mammalian cell-surface glycostructures, which participate in essential interaction processes including adhesion of pathogens prior to infection and immunogenicity. Here we present the synthesis and bioorthogonal metabolic incorporation of the sialic acid analogue N-(1-oxohex-5-ynyl)neuraminic acid (Neu5Hex) into the cell-surface glycocalyx of a human larynx carcinoma cell line (HEp-2) and its fluorescence labelling by click chemistry.

ChemInform Abstract: Synthesis of the First Sialic Acid Analogue Containing a γ-Pyrone Moiety.

ChemInform ◽  
2010 ◽  
Vol 31 (28) ◽  
pp. no-no
Author(s):  
Hua Chee Ooi ◽  
Sebastian M. Marcuccio ◽  
W. Roy Jackson ◽  
David F. O'Keefe
Keyword(s):  
Sialic Acid ◽  
Acid Analogue ◽  
Sialic Acid Analogue

Aromatic sialic acid analogues as potential inhibitors of influenza virus neuraminidase

Il Farmaco ◽  
2001 ◽  
Vol 56 (4) ◽  
pp. 305-309 ◽  
Author(s):  
Armandodoriano Bianco ◽  
Mario Brufani ◽  
Cristiana Melchioni
Keyword(s):  
Influenza Virus ◽  
Sialic Acid ◽  
Sialic Acid Analogues ◽  
Influenza Virus Neuraminidase ◽  
Potential Inhibitors
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