Multifunctional “Clickates” as Versatile Extended Heteroaromatic Building Blocks: Efficient Synthesis via Click Chemistry, Conformational Preferences, and Metal Coordination

2007 ◽  
Vol 13 (35) ◽  
pp. 9834-9840 ◽  
Author(s):  
Robert M. Meudtner ◽  
Marc Ostermeier ◽  
Richard Goddard ◽  
Christian Limberg ◽  
Stefan Hecht
Keyword(s):  
Click Chemistry ◽  
Building Blocks ◽  
Metal Coordination ◽  
Efficient Synthesis ◽  
Conformational Preferences

Non-Nucleoside Building Blocks for Copper-Assisted and Copper-Free Click Chemistry for the Efficient Synthesis of RNA Conjugates

2010 ◽  
Vol 12 (23) ◽  
pp. 5410-5413 ◽  
Author(s):  
K. N. Jayaprakash ◽  
Chang Geng Peng ◽  
David Butler ◽  
Jos P. Varghese ◽  
Martin A. Maier ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Building Blocks ◽  
Efficient Synthesis

Efficient Synthesis of Glycosylated Asparaginic Acid Building Blocks via Click Chemistry

Synthesis ◽  
2008 ◽  
Vol 2008 (4) ◽  
pp. 519-526 ◽  
Author(s):  
Thomas Ziegler ◽  
Nikolas Pietrzik ◽  
Carsten Schips
Keyword(s):  
Click Chemistry ◽  
Building Blocks ◽  
Efficient Synthesis ◽  
Asparaginic Acid

Dithiols as Liquid Crystalline Building Blocks for Smart Polymers via Thiol–yne Click Chemistry

2021 ◽  
Vol 3 (3) ◽  
pp. 1602-1609
Author(s):  
Flavia Lupi ◽  
Daniele Martella ◽  
Sara Nocentini ◽  
Diego Antonioli ◽  
Michele Laus ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Liquid Crystalline ◽  
Building Blocks ◽  
Smart Polymers

Highly efficient synthesis of polymer brushes with PEO and PCL as side chains via click chemistry

Polymer ◽  
2012 ◽  
Vol 53 (10) ◽  
pp. 1992-2000 ◽  
Author(s):  
Peng Zhao ◽  
Yechao Yan ◽  
Xiaoqin Feng ◽  
Lixin Liu ◽  
Chun Wang ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Polymer Brushes ◽  
Side Chains ◽  
Efficient Synthesis ◽  
Highly Efficient

Hierarchy of Supramolecular Arrangements and Building Blocks: Inverted Paradigm of Crystal Engineering in the Unprecedented Metal Coordination of Methylene Blue

2017 ◽  
Vol 56 (6) ◽  
pp. 3512-3516 ◽  
Author(s):  
Stefano Canossa ◽  
Alessia Bacchi ◽  
Claudia Graiff ◽  
Paolo Pelagatti ◽  
Giovanni Predieri ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Crystal Engineering ◽  
Building Blocks ◽  
Metal Coordination ◽  
Supramolecular Arrangements

Controlling chirality in the synthesis of 4 + 4 diastereomeric amine macrocycles derived from trans-1,2-diaminocyclopentane and 2,6-diformylpyridine.

2022 ◽  
Author(s):  
Dominka Fedorowicz ◽  
Sylwia Banach ◽  
Patrycja Koza ◽  
Rafał Frydrych ◽  
Katarzyna Ślepokura ◽  
...  
Keyword(s):  
Building Blocks ◽  
Efficient Synthesis

A few suitably long dialdehyde and primary diamine building blocks of a predetermined chirality have been designed and synthesized to enable controlled and efficient synthesis of all 6 possible diastereomers...

Design, synthesis and evaluation of structurally diverse ortho-acylphenol-diindolylmethane hybrids as anticancer agents

2022 ◽  
Author(s):  
Zhi-Gang Yin ◽  
Xiong-Wei Liu ◽  
Hui-Juan Wang ◽  
Min Zhang ◽  
Xiong-Li Liu ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Anticancer Agents ◽  
Nucleophilic Addition ◽  
Ring Opening ◽  
Building Blocks ◽  
Efficient Synthesis ◽  
Design Synthesis ◽  
Pyrone Ring ◽  
Ring Opening Reaction ◽  
First Time

A highly efficient synthesis of structurally diverse ortho-acylphenol–diindolylmethane hybrids 3 using carboxylic acid-activated chromones as versatile synthetic building blocks is reported here for the first time, through 1,4-nucleophilic addition and followed by a decarboxylation and pyrone ring opening reaction process.

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