scholarly journals Cover Feature: Supporting‐Electrolyte‐Free Electrochemical Methoxymethylation of Alcohols Using a 3D‐Printed Electrosynthesis Continuous Flow Cell System (ChemElectroChem 16/2019)

2019 ◽  
Vol 6 (16) ◽  
pp. 4063-4063
Author(s):  
Carlo G. W. van Melis ◽  
Matthew R. Penny ◽  
Anthony D. Garcia ◽  
Alessia Petti ◽  
Adrian P. Dobbs ◽  
...  
Keyword(s):  
Continuous Flow ◽  
Supporting Electrolyte ◽  
Flow Cell ◽  
Cell System ◽  
3D Printed

scholarly journals Supporting‐Electrolyte‐Free Electrochemical Methoxymethylation of Alcohols Using a 3D‐Printed Electrosynthesis Continuous Flow Cell System

2019 ◽  
Vol 6 (16) ◽  
pp. 4144-4148 ◽  
Author(s):  
Carlo G. W. van Melis ◽  
Matthew R. Penny ◽  
Anthony D. Garcia ◽  
Alessia Petti ◽  
Adrian P. Dobbs ◽  
...  
Keyword(s):  
Continuous Flow ◽  
Supporting Electrolyte ◽  
Flow Cell ◽  
Cell System ◽  
3D Printed

scholarly journals 3D-printed devices for continuous-flow organic chemistry

2013 ◽  
Vol 9 ◽  
pp. 951-959 ◽  
Author(s):  
Vincenza Dragone ◽  
Victor Sans ◽  
Mali H Rosnes ◽  
Philip J Kitson ◽  
Leroy Cronin
Keyword(s):  
Organic Chemistry ◽  
3D Printing ◽  
Continuous Flow ◽  
Flow Chemistry ◽  
Flow Cell ◽  
Proof Of Concept ◽  
Time Analysis ◽  
Real Time Analysis ◽  
Custom Made ◽  
3D Printed

We present a study in which the versatility of 3D-printing is combined with the processing advantages of flow chemistry for the synthesis of organic compounds. Robust and inexpensive 3D-printed reactionware devices are easily connected using standard fittings resulting in complex, custom-made flow systems, including multiple reactors in a series with in-line, real-time analysis using an ATR-IR flow cell. As a proof of concept, we utilized two types of organic reactions, imine syntheses and imine reductions, to show how different reactor configurations and substrates give different products.

scholarly journals Inline monitoring of high ammonia concentrations in methanol with a customized 3D printed flow cell

2021 ◽  
Author(s):  
Maximilian Maierhofer ◽  
Manuel C. Maier ◽  
Heidrun Gruber-Woelfler ◽  
Torsten Mayr
Keyword(s):  
Stainless Steel ◽  
Continuous Flow ◽  
Protective Layer ◽  
Flow Cell ◽  
Sensitive Material ◽  
Long Term Stability ◽  
Polyether Sulfone ◽  
3D Printed ◽  
Set Up ◽  
Polyurethane Hydrogel

AbstractA novel system for inline monitoring of ammonia (NH3) suitable for methanol is presented. An optical ammonia sensor with a response time t90 of 33 s was combined with a tailor-made, 3D printed flow cell and allowed efficient measurements under continuous flow. The optical sensor includes a fluorescent indicator dye that is physically immobilized into a polyurethane hydrogel. A protective layer made of hydrophobic polyether sulfone (PES) shields the ammonia sensitive material against interfering substances and guarantees long-term stability in methanol. The sensor can be read out via a compact phase fluorimeter. Measurements in continuous flow are enabled by a flow cell manufactured via selective laser melting (SLM) of stainless steel. Stainless steel was chosen for the flow cell due to its good heat transfer properties and relatively good chemical resistance of NH3 in methanol. The measurements were successfully carried out with ammonia concentrations between 0.3 and 5.6 mol L− 1 NH3 in methanol at 25 °C up to 80 °C. Additionally, different flow-rates (0.5–2.0 mL min− 1), varying internal pressure (0.5–2.0 bar) as well as reversibility of the measurements at 25 and 60 °C were studied in detail. The sensor did not degrade indicated by sufficient signal and low drift over a period of two weeks, thus indicating the high potential of the novel set-up for real-time measurements in continuous flow applications. Graphical abstract

Room Temperature Flow Electrochemistry as a Means of Retaining the “Memory of Chirality” via Hofer Moest Type Reaction

2020 ◽  
Author(s):  
Tomas Hardwick ◽  
Rossana Cicala ◽  
Nisar Ahmed
Keyword(s):  
Continuous Flow ◽  
Room Temperature ◽  
Biological Activities ◽  
Supporting Electrolyte ◽  
Enantiomeric Excess ◽  
Flow Chemistry ◽  
Batch Processes ◽  
Enabling Technology ◽  
Chiral Compounds ◽  
Memory Of Chirality

<p>Many chiral compounds have become of great interest to the pharmaceutical industry as they possess various biological activities. Concurrently, the concept of “memory of chirality” has been proven as a powerful tool in asymmetric synthesis, while flow chemistry has begun its rise as a new enabling technology to add to the ever increasing arsenal of techniques available to the modern day chemist. Here, we have employed a new simple electrochemical microreactor design to oxidise an L-proline derivative at room temperature in continuous flow. Flow performed in microreactors offers up a number of benefits allowing reactions to be performed in a more convenient and safer manner, and even allow electrochemical reactions to take place without a supporting electrolyte due to a very short interelectrode distance. By the comparison of electrochemical oxidations in batch and flow we have found that continuous flow is able to outperform its batch counterpart, producing a good yield (71%) and a better enantiomeric excess (64%) than batch with a 98% conversion. We have, therefore, provided evidence that continuous flow chemistry has the potential to act as a new enabling technology to replace some aspects of conventional batch processes. </p>

Chromatomembrane pre‐concentration of phenols using a new 3D printed micro flow cell followed by RP HPLC determination

2021 ◽  
Author(s):  
L.N. Moskvin ◽  
О.V. Rodinkov ◽  
А.L. Moskvin ◽  
V. Spivakovskii ◽  
A.Y. Vlasov ◽  
...  
Keyword(s):  
Flow Cell ◽  
Hplc Determination ◽  
Rp Hplc ◽  
Micro Flow ◽  
3D Printed

Monitoring of Microwave-Assisted Acid-Catalyzed Transesterification for Biodiesel Production Using FT-NIR Spectroscopy with Continuous-Flow Cell

2015 ◽  
Vol 3 (1) ◽  
pp. 68-77 ◽  
Author(s):  
Evandro L. Dall'Oglio ◽  
Paulo T. de Sousa ◽  
Leonardo Gomes de Vasconcelos ◽  
Carlos Adriano Parizotto ◽  
Ewerton Ferreira Barros ◽  
...  
Keyword(s):  
Continuous Flow ◽  
Nir Spectroscopy ◽  
Flow Cell ◽  
Biodiesel Production ◽  
Microwave Assisted ◽  
Acid Catalyzed
Sign in / Sign up

Export Citation Format

Share Document