Asymmetrical Microchannel Emulsification Plates for Production of Small-Sized Monodispersed Emulsion Droplets

2017 ◽  
Vol 40 (12) ◽  
pp. 2351-2355 ◽  
Author(s):  
Nauman Khalid ◽  
Isao Kobayashi ◽  
Kunihiko Uemura ◽  
Mitsutoshi Nakajima
Keyword(s):  
Microchannel Emulsification ◽  
Emulsion Droplets

β-lactoglobulin as food grade surfactant for clove oil-in-water and limonene-in-water emulsion droplets produced by microchannel emulsification

2016 ◽  
Vol 60 ◽  
pp. 98-108 ◽  
Author(s):  
Nanik Purwanti ◽  
Sosaku Ichikawa ◽  
Marcos A. Neves ◽  
Kunihiko Uemura ◽  
Mitsutoshi Nakajima ◽  
...  
Keyword(s):  
Clove Oil ◽  
Water Emulsion ◽  
Food Grade ◽  
Microchannel Emulsification ◽  
Emulsion Droplets ◽  
Oil In Water ◽  
Β Lactoglobulin

Formulation characteristics of triacylglycerol oil-in-water emulsions loaded with ergocalciferol using microchannel emulsification

RSC Advances ◽  
2015 ◽  
Vol 5 (118) ◽  
pp. 97151-97162 ◽  
Author(s):  
Nauman Khalid ◽  
Isao Kobayashi ◽  
Zheng Wang ◽  
Marcos A. Neves ◽  
Kunihiko Uemura ◽  
...  
Keyword(s):  
Encapsulation Efficiency ◽  
Storage Period ◽  
Food Grade ◽  
Microchannel Emulsification ◽  
Emulsion Droplets ◽  
Oil In Water

Food grade monodisperse O/W emulsions encapsulating ergocalciferol have been formulated using microchannel emulsification. The O/W emulsion droplets have an encapsulation efficiency of over 75% within the evaluated storage period.

Highly paralleled emulsion droplets for efficient isolation, amplification, and screening of cancer biomarker binding phages

Lab on a Chip ◽  
2021 ◽  
Author(s):  
Junxia Wang ◽  
Yuyu Tan ◽  
Jiajun Ling ◽  
Mingxia Zhang ◽  
Liang Li ◽  
...  
Keyword(s):  
Traditional Approach ◽  
Cancer Biomarker ◽  
Highly Efficient ◽  
Whole Process ◽  
Emulsion Droplets ◽  
Ligand Screening

The double monoclonal display (dm-Display) has realized highly efficient monoclonal ligand screening, which can accelerate the whole process from weeks to 24 h with clone characterization throughput 1000-time higher than that of traditional approach.

scholarly journals Fabrication of Multi-Layered Microspheres Based on Phase Separation for Drug Delivery

Micromachines ◽  
2021 ◽  
Vol 12 (6) ◽  
pp. 723
Author(s):  
He Xia ◽  
Ang Li ◽  
Jia Man ◽  
Jianyong Li ◽  
Jianfeng Li
Keyword(s):  
Aqueous Solution ◽  
Phase Separation ◽  
Gastric Fluid ◽  
Simulated Gastric Fluid ◽  
Sustained Drug Release ◽  
Simulated Intestinal Fluid ◽  
Glycol Diacrylate ◽  
Emulsion Droplets ◽  
Collection Tube ◽  
Poly Ethylene

In this work, we used a co-flow microfluidic device with an injection and a collection tube to generate droplets with different layers due to phase separation. The phase separation system consisted of poly(ethylene glycol) diacrylate 700 (PEGDA 700), PEGDA 250, and sodium alginate aqueous solution. When the mixture droplets formed in the outer phase, PEGDA 700 in the droplets would transfer into the outer aqueous solution, while PEGDA 250 still stayed in the initial droplet, breaking the miscibility equilibrium of the mixture and triggering the phase separation. As the phase separation proceeded, new cores emerged in the droplets, gradually forming the second and third layers. Emulsion droplets with different layers were polymerized under ultraviolet (UV) irradiation at different stages of phase separation to obtain microspheres. Microspheres with different layers showed various release behaviors in simulated gastric fluid (SGF) and simulated intestinal fluid (SIF). The release rate decreased with the increase in the number of layers, which showed a potential application in sustained drug release.

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