Highly paralleled emulsion droplets for efficient isolation, amplification, and screening of cancer biomarker binding phages

Lab on a Chip ◽  
2021 ◽  
Author(s):  
Junxia Wang ◽  
Yuyu Tan ◽  
Jiajun Ling ◽  
Mingxia Zhang ◽  
Liang Li ◽  
...  
Keyword(s):  
Traditional Approach ◽  
Cancer Biomarker ◽  
Highly Efficient ◽  
Whole Process ◽  
Emulsion Droplets ◽  
Ligand Screening

The double monoclonal display (dm-Display) has realized highly efficient monoclonal ligand screening, which can accelerate the whole process from weeks to 24 h with clone characterization throughput 1000-time higher than that of traditional approach.

scholarly journals Big data analytics of the technological equipment based on Data Lake architecture

2019 ◽  
Vol 298 ◽  
pp. 00079 ◽  
Author(s):  
Ilya Kovalev ◽  
Ramil Nezhmetdinov ◽  
Denis Kvashnin
Keyword(s):  
Data Aggregation ◽  
Industry 4.0 ◽  
Data Analytics ◽  
Traditional Approach ◽  
Big Data Analytics ◽  
Digital Transformation ◽  
Industrial Enterprises ◽  
Industrial Companies ◽  
Whole Process ◽  
Almost All

Currently, more and more managers of medium and large industrial companies are thinking about conducting a digital transformation of their enterprise. Each company is forced to strive to find an approach to optimizing production in order to remain competitive in the market. For industrial enterprises, this approach may be a digital transformation using the ideas of Industry 4.0. The digital transformation of an enterprise is a complex and multifaceted process that affects almost all levels of production. At the head of this whole process are data. Data on the work of production must be collected, stored, aggregated, transferred to various levels. Existing methods for storing data are not always suitable for working with BigData, new solutions are needed. The paper shows a comparison of the traditional approach to data aggregation and a promising direction based on the architecture of Data Lake.

Perspectives on Drug Repurposing

2020 ◽  
Vol 27 ◽  
Author(s):  
Alejandro Schcolnik-Cabrera ◽  
Daniel Juárez-López ◽  
Alfonso Duenas-Gonzalez
Keyword(s):  
Traditional Approach ◽  
Current Model ◽  
Drug Repurposing ◽  
Novel Treatments ◽  
Whole Process ◽  
Development Costs ◽  
Health Community ◽  
Significant Burden ◽  
High Investment ◽  
Private Investors

: Complex common diseases are a significant burden for our societies and demand not only preventive measures but also more effective, safer, and more affordable treatments. The whole process of the current model of drug discovery and development implies a high investment by the pharmaceutical industry, which ultimately impact in high drug prices. In this sense, drug repurposing would help meet the needs of patients to access useful and novel treatments. Unlike the traditional approach, drug repurposing enters both the preclinical evaluation and clinical trials of the compound of interest faster, budgeting research and development costs, and limiting potential biosafety risks. The participation of government, society, and private investors is needed to secure the funds for experimental design and clinical development of repurposing candidates to have affordable, effective, and safe repurposed drugs. Moreover, extensive advertising of repurposing as a concept in the health community, could reduce prescribing bias when enough clinical evidence exists, which will support the employment of cheaper and more accessible repurposed compounds for common conditions.

Highly efficient Polyaniline-MoS2 hybrid nanostructures based biosensor for cancer biomarker detection

2019 ◽  
Vol 1055 ◽  
pp. 26-35 ◽  
Author(s):  
Amrita Soni ◽  
Chandra Mouli Pandey ◽  
Manoj Kumar Pandey ◽  
Gajjala Sumana
Keyword(s):  
Cancer Biomarker ◽  
Hybrid Nanostructures ◽  
Biomarker Detection ◽  
Highly Efficient

Towards highly efficient solar-driven interfacial evaporation for desalination

2020 ◽  
Vol 8 (35) ◽  
pp. 17907-17937 ◽  
Author(s):  
Xinghang Liu ◽  
Debesh Devadutta Mishra ◽  
Xianbao Wang ◽  
Hongyan Peng ◽  
Chaoquan Hu
Keyword(s):  
Energy Flow ◽  
Highly Efficient ◽  
Whole Process ◽  
Critical Issues

This review systematically discusses the whole process of solar-driven interfacial desalination and the critical issues involved from the perspective of energy flow.

Highly efficient and selective photocatalytic CO2 to CO conversion in aqueous solution

2020 ◽  
Vol 56 (27) ◽  
pp. 3851-3854 ◽  
Author(s):  
Xiaomin Chai ◽  
Hai-Hua Huang ◽  
Huiping Liu ◽  
Zhuofeng Ke ◽  
Wen-Wen Yong ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Photocatalytic Performance ◽  
Aqueous Media ◽  
Highly Efficient ◽  
Co Conversion

A Co-based complex displayed the highest photocatalytic performance for CO2 to CO conversion in aqueous media.

Tuning the pore structures and photocatalytic properties of a 2D covalent organic framework with multi-branched photoactive moieties

Nanoscale ◽  
2020 ◽  
Vol 12 (30) ◽  
pp. 16136-16142
Author(s):  
Xuan Wang ◽  
Ming-Jie Dong ◽  
Chuan-De Wu
Keyword(s):  
Photocatalytic Properties ◽  
Effective Strategy ◽  
Covalent Organic Framework ◽  
Highly Efficient ◽  
Pore Structures ◽  
Local Connection ◽  
Organic Framework

An effective strategy to incorporate accessible metalloporphyrin photoactive sites into 2D COFs by establishing a 3D local connection for highly efficient photocatalysis was developed.

Perceptions of a Peer Suicide Prevention Program by Inmates and Professionals Working in Prisons

Crisis ◽  
2013 ◽  
Vol 34 (4) ◽  
pp. 289-292 ◽  
Author(s):  
Laurent Auzoult ◽  
Sid Abdellaoui
Keyword(s):  
Suicide Prevention ◽  
Prevention Program ◽  
Suicide Risk ◽  
Traditional Approach ◽  
Prevention Programs ◽  
New Methods ◽  
Penal Institutions ◽  
Peer Suicide ◽  
Suicide Prevention Programs ◽  
Methods Of Suicide

Background: Suicide prevention is a major challenge for penal institutions in many countries. The traditional approach relies on the expertise of health professionals and is supplemented by the intervention of other professionals and the inmates themselves. New methods of suicide prevention based on peer support have been developed in recent years. Peer prevention programs rely on the ability of inmates to identify suicide risk. Aims: This study examines perceived suicide risk among inmates and explores possible explanations. Method: 54 inmates and 17 professionals working in prisons responded to a questionnaire. Results: The peer prevention program was found to change inmates’ expectations of support in the event of a suicide crisis. The study also found that the inmates involved in the program tended to underestimate the risk of suicide. The perception of the prevention program and the level of self-consciousness were found to account for the underestimation of suicide risk. Conclusions: Support for inmates involved in suicide prevention programs must take into account their isolation in prison. The training provided to inmates must also consider the biases affecting the assessment of risk.

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