scholarly journals Diagnostic significance of fat globules in blood in fulminant‐type fat embolism syndrome

2021 ◽  
Vol 9 (10) ◽  
Author(s):  
Ayu Asakage ◽  
Michiko Fujisawa ◽  
Tetsuhiro Takei ◽  
Jiro Kumagai
Keyword(s):  
Fat Embolism ◽  
Diagnostic Significance ◽  
Fat Embolism Syndrome ◽  
Fat Globules ◽  
Embolism Syndrome ◽  
Fulminant Type

scholarly journals Diagnostic significance of fat globules in blood in fulminant-type fat embolism syndrome

2021 ◽  
Author(s):  
AYU ASAKAGE ◽  
Michiko Fujisawa ◽  
Tetsuhiro Takei ◽  
Jiro Kumagai
Keyword(s):  
Fat Embolism ◽  
Quantitative Change ◽  
Diagnostic Significance ◽  
Fat Embolism Syndrome ◽  
Fat Globules ◽  
Embolism Syndrome ◽  
The Future ◽  
Life Threatening ◽  
Fulminant Type

Detecting fat globules in blood in diagnosing fat embolism syndrome (FES) remains controversial. This case illustrated two life threatening episodes possibly due to FES, with a dramatic increases of fat globules in blood. Significance of quantitative change of fat in blood in diagnosing FES should be evaluated in the future.

A Case of Fat Embolism Syndrome of Fat Globules Found in BAL Fluid after Recovery from Acute Respiratory Failure

2006 ◽  
Vol 61 (6) ◽  
pp. 562
Author(s):  
Song Ree Park ◽  
Hyun Soo Kim ◽  
Jae Hyung Lee ◽  
Sang Heon Kim ◽  
Tae Hyung Kim ◽  
...  
Keyword(s):  
Respiratory Failure ◽  
Acute Respiratory Failure ◽  
Fat Embolism ◽  
Fat Embolism Syndrome ◽  
Fat Globules ◽  
Embolism Syndrome

Fat Embolism Syndrome

2010 ◽  
pp. 34-46
Author(s):  
Edward C. Rosenow
Keyword(s):  
Aortic Arch ◽  
Bone Fracture ◽  
Fat Embolism ◽  
Long Bone ◽  
Fat Embolism Syndrome ◽  
Fat Globules ◽  
Direct Trauma ◽  
Embolism Syndrome ◽  
Long Bone Fracture

Biopsy of these petechiae would show fat globules in the small arterioles. Such petechiae are theorized to occur only above the level of the diaphragm because the fat floats and is spun off in the aortic arch into the subclavian and innominate vessels • Within 48 hours of a long-bone fracture, the following develop (unrelated to direct trauma):...

scholarly journals Fat embolism syndrome: choice and effectiveness of laboratory diagnostic methods

2019 ◽  
Vol 1 (2) ◽  
pp. 71-82
Author(s):  
Vladimir Karpov ◽  
Irina Kleina ◽  
Sergey Kazakov ◽  
Daniil Korabelnikov ◽  
Shamil' Gizatullin
Keyword(s):  
Laboratory Diagnosis ◽  
Surfactant Protein ◽  
Fat Embolism ◽  
Diagnostic Methods ◽  
Laboratory Diagnostics ◽  
Diagnostic Significance ◽  
Fat Embolism Syndrome ◽  
Embolism Syndrome ◽  
Protein S100b ◽  
The Relationship

The review on the use of traditional and new methods of laboratory diagnostics of fat embolism syndrome - a complication that in some cases asymptomatically accompanies severe concomitant trauma is presented. The main currently used laboratory diagnostic methods are described: traditional methods and new markers (interleukin-6, neuroglial protein S100B, surfactant protein SP-D). A review of the literature data in terms of assessing the pathogenetic and diagnostic significance of some methods of laboratory diagnosis of fat embolism syndrome, the relationship between the dynamics of the considered laboratory parameters, the clinical picture and inflammation. Own observation is presented. The results show the importance of integrating the whole range of available methods in the diagnosis of fat embolism syndrome.

scholarly journals Fat Embolism Syndrome in Sickle Cell β-Thalassemia Patient With Osteonecrosis: An Uncommon Presentation in a Young Adult

2021 ◽  
Vol 9 ◽  
pp. 232470962110122
Author(s):  
Vikram Sangani ◽  
Mytri Pokal ◽  
Mamtha Balla ◽  
Ganesh Prasad Merugu ◽  
Waleed Khokher ◽  
...  
Keyword(s):  
Sickle Cell ◽  
Exchange Transfusion ◽  
Bone Fractures ◽  
Fat Embolism ◽  
Long Bone ◽  
Red Cell ◽  
Fat Embolism Syndrome ◽  
Fat Globules ◽  
Embolism Syndrome ◽  
Uncommon Presentation

Fat embolism syndrome is a relatively infrequent presentation in sickle cell thalassemia patients. It most commonly occurs in long bone fractures in the setting of trauma. However, nonorthopedic trauma and nontraumatic cases have been reported to contribute to fat embolism. The fat embolic syndrome is an underdiagnosed, life-threatening, and debilitating complication of sickle-β-thalassemia–related hemoglobinopathies. It is primarily seen in milder versions of sickle cell disease, including HbSC and sickle cell β-thalassemia, with the mild prior clinical course without complications; hence, diagnosis can be easily missed. Pathogenesis of fat embolic syndrome is a combination of mechanical obstruction from fat globules released into systemic circulation at the time of bone marrow necrosis and direct tissue toxicity from fatty acids and inflammatory cytokines released from fat globules. Prompt diagnosis and early initiation of treatment can reduce morbidity and mortality and result in better outcomes and prognosis. Red cell exchange transfusion is the mainstay of therapy with mortality benefits. Overall mortality and neurological sequelae continue to be high despite increased red cell exchange transfusion in the last few years. In this article, we discussed a case of a 34-year-old male patient with a history of sickle cell thalassemia and avascular necrosis of the hip, who presented with fever, hypoxia, encephalopathy, and generalized body aches, found to have thrombocytopenia and punctate lesions on magnetic resonance imaging brain, which led to the diagnosis of the fat embolism syndrome. Only a few sickle cell β-thalassemia with fat embolic syndrome cases have been reported.

Clinical case of successful treatment of compartment syndrome, complicated by fat embolism syndrome

2018 ◽  
Vol 16 (7(part 1)) ◽  
pp. 81-84
Author(s):  
I. O. Pankov ◽  
◽  
M. M. Gabdullin ◽  
S. D. Sirazitdinov ◽  
◽  
...  
Keyword(s):  
Compartment Syndrome ◽  
Successful Treatment ◽  
Clinical Case ◽  
Fat Embolism ◽  
Fat Embolism Syndrome ◽  
Embolism Syndrome

scholarly journals Late-onset isolated cerebral fat embolism syndrome after a simple tibial plateau fracture: a rare case report

2021 ◽  
Vol 49 (7) ◽  
pp. 030006052110284
Author(s):  
Ta-Li Hsu ◽  
Tien-Chi Li ◽  
Fei-Pi Lai ◽  
Ming Ouhyoung ◽  
Chih-Hung Chang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Rare Case ◽  
Tibial Plateau ◽  
Tibial Plateau Fracture ◽  
Fat Embolism ◽  
Resonance Imaging ◽  
Fat Embolism Syndrome ◽  
Embolism Syndrome ◽  
Plateau Fracture

Fat embolism syndrome (FES) is a complication of long bone fractures that often occurs within 72 hours of injury. Early-onset isolated cerebral fat embolism is catastrophic and rarely reported. We herein present a rare case of delayed-onset isolated cerebral FES that developed 10 days after definite fixation of a left tibial plateau fracture. A 70-year-old woman was injured in a traffic accident and diagnosed with a left tibial plateau fracture. However, she developed sudden loss of consciousness (E4V1M1) and quadriplegia 10 days after fracture fixation. Her vital signs showed no respiratory distress. Diagnosis of isolated cerebral FES was made based on magnetic resonance imaging of the brain, the findings of which were compatible with the clinical neurological findings. After supportive care and rehabilitation, her consciousness became clear on the second day of admission, and her consciousness changed to E4V5M6. She gradually regained strength in her right limbs but had residual left limb paraplegia. Isolated cerebral FES should always be considered for patients who develop a change in consciousness, even beyond 72 hours after injury. Imaging may not initially show definitive abnormalities. Repeated magnetic resonance imaging should be considered if the initial clinical presentation does not fully meet Gurd’s criteria.

scholarly journals A rare case of fat embolism syndrome secondary to abdominal liposuction and gluteal fat infiltration

2020 ◽  
Vol 2020 (12) ◽  
Author(s):  
Salvador Recinos ◽  
Sabrina Barillas ◽  
Alejandra Rodas ◽  
Javier Ardebol
Keyword(s):  
Right Ventricular Dysfunction ◽  
Signs And Symptoms ◽  
Fat Embolism ◽  
Fat Infiltration ◽  
Fat Embolism Syndrome ◽  
Embolism Syndrome ◽  
Threatening Condition ◽  
Life Threatening ◽  
Bone Marrow Harvesting ◽  
Dermatologic Manifestations

Abstract Fat embolism syndrome (FES) is a rare, life-threatening condition habitually associated with traumatic events such as fractures and, less commonly, burns, liposuction and bone marrow harvesting and transplant [ 1]. The biochemical theory for this condition suggests that fat droplets embolize and convert into fatty acids, eventually leading to toxic injury and inflammation, which results in increased vascular permeability, edema and hemorrhage [ 2]. FES may have an asymptomatic interval lasting 12–72 hours after the insult; however, in some cases, signs have also been seen intraoperatively. Pulmonary signs and symptoms are customarily the earliest and manifest in 75% of patients. Nevertheless, neurologic and dermatologic manifestations are also characteristic, and most severe cases could perhaps present with disseminated intravascular coagulation, right ventricular dysfunction, shock or death. The following case consists of a 37-year-old patient that presented with fat embolism syndrome during liposuction and gluteal fat infiltration.

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