scholarly journals Combination of varenicline and nicotine patch for smoking cessation: A case report

2019 ◽  
Vol 7 (9) ◽  
pp. 1670-1672
Author(s):  
Kelly M. Young ◽  
James M. Davis
Keyword(s):  
Smoking Cessation ◽  
Case Report ◽  
Nicotine Patch

The effectiveness of nicotine-patch therapy for smoking cessation in patients with schizophrenia

2004 ◽  
Vol 41 (3) ◽  
pp. 321-330 ◽  
Author(s):  
Kuei-Ru Chou ◽  
Ruey Chen ◽  
Jia-Fu Lee ◽  
Chih-Hung Ku ◽  
Ru-Band Lu
Keyword(s):  
Smoking Cessation ◽  
Nicotine Patch

scholarly journals Nicotine patch vs. nicotine lozenge for smoking cessation: An effectiveness trial coordinated by the Community Clinical Oncology Program

2010 ◽  
Vol 107 (2-3) ◽  
pp. 237-243 ◽  
Author(s):  
Robert A. Schnoll ◽  
Elisa Martinez ◽  
Kristina L. Tatum ◽  
Marcella Glass ◽  
Albert Bernath ◽  
...  
Keyword(s):  
Smoking Cessation ◽  
Clinical Oncology ◽  
Nicotine Patch ◽  
Effectiveness Trial ◽  
Community Clinical Oncology Program ◽  
Nicotine Lozenge

scholarly journals Study Characteristics Influence the Efficacy of Substance Abuse Treatments: A Meta-analysis of Medications for Smoking Cessation

2018 ◽  
Vol 22 (3) ◽  
pp. 317-323 ◽  
Author(s):  
Elias M Klemperer ◽  
John R Hughes ◽  
Shelly Naud
Keyword(s):  
Smoking Cessation ◽  
Treatment Efficacy ◽  
Linear Models ◽  
Nicotine Patch ◽  
Meta Analysis ◽  
Individual Characteristics ◽  
Odds Ratios ◽  
Industry Funding ◽  
Cochrane Reviews ◽  
Study Characteristics

Abstract Background Understanding study characteristics’ influence on treatment efficacy could improve interpretation of trials’ outcomes. We examined study characteristics as predictors of outcomes in clinical trials of medications for tobacco use. Methods We obtained and analyzed data on 44 trials of nicotine gum, 37 trials of nicotine patch, 27 trials of varenicline, and 43 trials of bupropion from Cochrane reviews. We extracted and analyzed data for 15 study characteristics, odds ratios (ORs), and percent abstinent in control and medication conditions. We used general linear models to determine which study characteristics explained the variability among outcomes after controlling for medication characteristics. Results Study characteristics accounted for 12% of the variance in odds ratios among patch trials, 16% among gum trials, 16% among varenicline trials, and 34% among bupropion trials above and beyond medication characteristics. Patch and gum trials with industry funding had larger odds ratios than those without. Among patch trials, this appeared to be due to less abstinence in industry-funded trials’ control conditions. Bupropion trials published earlier had larger odds ratios, which appeared to be due to less abstinence in control conditions. The reason for study characteristics’ influence on varenicline trials was unclear. Discussion Study characteristics influenced the assessment of treatment efficacy above and beyond medication characteristics in smoking cessation trials. Our findings that study characteristics are associated with higher or lower efficacy does not suggest that the effect size under one versus another condition is the more valid outcome. Future studies are needed to determine which study characteristics reliably influence efficacy because this would help investigators and clinicians interpret trials. Implications Study characteristics influenced the estimates of treatment efficacy but individual characteristics’ influence on efficacy appeared to differ among different medications for smoking cessation. We encourage researchers to report study characteristics to improve interpretation of findings and systematic reviews, and to account for nontreatment-related variables to better estimate the efficacy of treatments.

Combination Rapid-Acting Nicotine Mouth Spray and Nicotine Patch Therapy in Smoking Cessation

2014 ◽  
Vol 16 (10) ◽  
pp. 1356-1364 ◽  
Author(s):  
Brent O. Caldwell ◽  
Simon J. Adamson ◽  
Julian Crane
Keyword(s):  
Smoking Cessation ◽  
Nicotine Patch
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