scholarly journals Tyrosine kinase inhibitor and rituximab-CHOP treatment for concurrent chronic myeloid leukemia and non-Hodgkin lymphoma: a case report

2017 ◽  
Vol 5 (12) ◽  
pp. 2047-2050
Author(s):  
Yuki Takeyasu ◽  
Atsushi Satake ◽  
Yoshiko Azuma ◽  
Yukie Tsubokura ◽  
Hideaki Yoshimura ◽  
...  
Keyword(s):  
Case Report ◽  
Chronic Myeloid Leukemia ◽  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Hodgkin Lymphoma ◽  
Myeloid Leukemia ◽  
Kinase Inhibitor ◽  
Non Hodgkin Lymphoma

scholarly journals Pancytopenia during tyrosine kinase inhibitor treatment – coexistence of chronic myeloid leukemia and visceral leishmaniasis: a case report

2016 ◽  
Vol 10 (1) ◽  
Author(s):  
Acy Quixada ◽  
Pedro Aurio Maia Filho ◽  
Tarcísio Paulo Almeida Filho ◽  
Fernando Barroso Duarte ◽  
Caroline Aquino Moreira-Nunes ◽  
...  
Keyword(s):  
Case Report ◽  
Chronic Myeloid Leukemia ◽  
Visceral Leishmaniasis ◽  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Myeloid Leukemia ◽  
Kinase Inhibitor ◽  
Inhibitor Treatment

Eradication of T315I mutation in chronic myeloid leukemia without third-generation tyrosine kinase inhibitor: a case report

2015 ◽  
Vol 16 (7) ◽  
pp. 677-679 ◽  
Author(s):  
Geoffroy Venton ◽  
Julien Colle ◽  
Cedric Mercier ◽  
Raphaelle Fanciullino ◽  
Joseph Ciccolini ◽  
...  
Keyword(s):  
Case Report ◽  
Chronic Myeloid Leukemia ◽  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Myeloid Leukemia ◽  
Kinase Inhibitor ◽  
Third Generation ◽  
T315i Mutation

scholarly journals Case Report: Priapism as The Clinical Presenting Feature of Chronic Myeloid Leukemia: Case Report and 20-Year Literature Review

F1000Research ◽  
2022 ◽  
Vol 10 ◽  
pp. 571
Author(s):  
Siprianus Ugroseno Yudho Bintoro ◽  
Pradana Zaky Romadhon ◽  
Satriyo Dwi Suryantoro ◽  
Rusdi Zakki Aminy ◽  
Choirina Windradi ◽  
...  
Keyword(s):  
Case Report ◽  
Early Intervention ◽  
Chronic Myeloid Leukemia ◽  
Literature Review ◽  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Myeloid Leukemia ◽  
Kinase Inhibitor ◽  
Blood Aspiration

Priapism in chronic myeloid leukemia (CML) appears to be an infrequent manifestation as well as a crucial emergency. Here, we report an 18-year-old male presenting with a persistent erection of the penis for 20 days. We evaluated and compared the reported cases within 20 years discussing the management of priapism in CML. Cytoreductive therapy followed by leukapheresis, the administration of tyrosine kinase inhibitor, and intra-cavernosal blood aspiration may resolve the symptoms of priapism. Early intervention for cytoreduction and aspiration are the pivotal keys to successfully impeding the complications.

Treatment of Chronic Myeloid Leukemia Elderly Patients in the Tyrosine Kinase Inhibitor Era

2013 ◽  
Vol 13 (7) ◽  
pp. 755-767 ◽  
Author(s):  
Domenico Russo ◽  
Michele Malagola ◽  
Cristina Skert ◽  
Carla Filì ◽  
Cesare Bergonzi ◽  
...  
Keyword(s):  
Chronic Myeloid Leukemia ◽  
Elderly Patients ◽  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Myeloid Leukemia ◽  
Kinase Inhibitor

scholarly journals Thrombotic microangiopathy in dasatinib-treated patients with chronic myeloid leukemia

2019 ◽  
Vol 4 (1-2) ◽  
pp. 41-45 ◽  
Author(s):  
Takeo Koshida ◽  
Sylvia Wu ◽  
Hitoshi Suzuki ◽  
Rimda Wanchoo ◽  
Vanesa Bijol ◽  
...  
Keyword(s):  
Chronic Myeloid Leukemia ◽  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Tyrosine Kinase Inhibitors ◽  
Thrombotic Microangiopathy ◽  
Myeloid Leukemia ◽  
Kinase Inhibitors ◽  
Kidney Biopsy ◽  
Kinase Inhibitor ◽  
Target Effect

Dasatinib is the second-generation tyrosine kinase inhibitor used in the treatment of chronic myeloid leukemia. Proteinuria has been reported with this agent. We describe two kidney biopsy–proven cases of dasatinib-induced thrombotic microangiopathy that responded to stoppage of dasatinib and using an alternate tyrosine kinase inhibitor. Certain specific tyrosine kinase inhibitors lead to endothelial injury and renal-limited thrombotic microangiopathy. Hematologists and nephrologists need to be familiar with this off-target effect of dasatinib.

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