scholarly journals Gitelman syndrome: a rare life-threatening case of hypokalemic paralysis mimicking Guillain-Barré syndrome during pregnancy and review of the literature

2017 ◽  
Vol 5 (10) ◽  
pp. 1597-1603 ◽  
Author(s):  
Abdelghafour Elkoundi ◽  
Noureddine Kartite ◽  
Mustapha Bensghir ◽  
Nawfal Doghmi ◽  
Salim Jaafar Lalaoui
2018 ◽  
Vol 1 (1) ◽  

Guillain-Barre Syndrome (GBS) is a post-infectious neuropathy typically described as a bilateral ascending paralysis of the lower extremities. There are, however, multiple lesser known subtypes of the syndrome that can affect both adult and pediatric populations. The Pharyngeal- Brachial-Cervical (PCB) variant is one of the rarer forms, which presents with weakness of the neck, oropharynx, and upper extremities. This atypical presentation can be confused with other diagnoses, and early detection is important for preventing potentially life-threatening complications. To date, only ten cases of this entity have been reported in children. Below we report on a 15-year-old female who presented with left arm weakness who subsequently progressed to classic GBS and review the literature on this GBS variant in children.


2018 ◽  
Vol 09 (02) ◽  
Author(s):  
Sawsan Daoud ◽  
Nouha Farhat ◽  
Hanen Haj Kacem ◽  
Olfa Hdiji ◽  
Salma Sakka ◽  
...  

Author(s):  
Pariwat Thaisetthawatkul ◽  
Eric Logigian

Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) are both immune-mediated diseases of the peripheral nervous system that typically present with symmetric, progressive muscle weakness, areflexia, and sensory symptoms or signs. GBS evolves rapidly with a nadir at 2–4 weeks usually with an antecedent viral illness, while CIDP progresses more slowly over months to years. GBS is sometimes complicated by life-threatening respiratory failure or dysautonomia. Onset of GBS and relapse of CIDP can occur during pregnancy or postpartum. But with appropriate supportive care and immunotherapy, maternal and fetal outcome in both conditions is typically excellent. The exception is fetal outcome in GBS triggered by maternal CMV or Zika infection transmitted to the fetus. Full-term vaginal delivery and regional anesthesia are preferred in maternal GBS and CIDP, but if C-section and general anesthesia are indicated, non-depolarizing agents such as succinylcholine should be avoided.


2015 ◽  
Vol 44 (4) ◽  
pp. 249-254 ◽  
Author(s):  
Wan-Chun Huang ◽  
Chin-Li Lu ◽  
Solomon Chih-Cheng Chen

Background: Guillain-Barré syndrome (GBS) is a potentially life-threatening disease that typically occurs after a preceding infectious disease. An accurate estimation of GBS incidence would be useful for investigating the potential causal relationships between risk factors and GBS. Here we described the nationwide incidence of GBS in Taiwan. Methods: The cases of GBS were obtained from all admission records of the National Health Insurance Research Database. We identified all of the first-admitted GBS patients by a code of ICD-9-CM 357.0 presented at the discharge diagnoses in admission records between 1997 and 2011. Calendar year, age, and sex-specific incidence, and seasonal variation were estimated. Results: A total of 5,998 patients were identified. The male-to-female rate ratio was 1.54. The crude incidence rate was 1.65 per 100,000 person-years. The incidence of GBS was lowest in people aged less than 20 and increased with age, especially in people older than 50 years. In spring, the incidence was 10% higher than in other seasons. Conclusions: The overall incidence is in line with previous large-scale studies. A significant higher rate in spring is also shown. The potential reasons for the seasonality and higher incidence among older patients should be further investigated.


Praxis ◽  
2021 ◽  
Vol 110 (3) ◽  
pp. 160-163
Author(s):  
Corinne Chmiel ◽  
Christian Giambarba ◽  
Johannes Trachsler

Abstract. This case of ascending paralysis, following an episode of diarrhea, was initially misinterpreted as Guillain-Barré syndrome. The prominent hypokalemia led to the search for other differential diagnoses, initially interpreted as a rare case of periodic hypokalemic paralysis, which usually occurs in Asians after intake of large amounts of starch foods, such as Spaghetti, or rest after heavy exercise. In this case, the reason for the hypokalemia with associated paralysis was caused by a hyperhyreosis factitia through denied intake of T3.


2009 ◽  
Vol 21 (2) ◽  
pp. 72-75
Author(s):  
Debasish Banik ◽  
Qumrul Huda ◽  
Labib Imran Faruque ◽  
Md Abdul Hye

Acute polyneuropathy or Guillain Barré syndrome (GBS) following respiratory, gastrointestinal and other illness cause a world wide morbidity and mortality. Immunotherapy (IgG) is early phase of GBS is supposed to reduce life threatening complications. In our retrospective study in ICU, BSMMU Dhaka from January 2007 to December 2008, we included 43 patients admitted during that time. Among the patients 15 patients who received IgG therapy, 1 (one) patient died and 8 patients died among 28 who did not receive Immunotherapy. Recovery rate was 91.66% among IgG group and 66.67% in non IgG group. Ventilated Patients were 53.33% in IgG group and 71.43% patients were in non IgG group. The average duration of stay was 35 days in IgG group and 39.18 days in non-IgG group. The average duration of stay was 22.57 days in IgG group who received immunotherapy in 0-4 days of onset of symptoms and 45.88 days in who got immunotherapy in 5-8 days of onset of symptoms. It is clearly evident that IgG therapy in early phase of GBS reduces, morality, morbidity and duration of hospital (ICU) stay and IgG therapy in early phase of GBS is a better treatment option. Key Words: GBS, immunoglobulin. Journal of BSA, 2008; 21(2): 72-75


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