What are the benefits and harms of interventions for people with chronic pruritus of unknown origin?

2020 ◽  
Author(s):  
Karen Pettersen ◽  
Sera Tort
Keyword(s):  
Unknown Origin ◽  
Chronic Pruritus

scholarly journals Pathophysiology and Treatment of Pruritus in Elderly

2020 ◽  
Vol 22 (1) ◽  
pp. 174
Author(s):  
Bo Young Chung ◽  
Ji Young Um ◽  
Jin Cheol Kim ◽  
Seok Young Kang ◽  
Chun Wook Park ◽  
...  
Keyword(s):  
Skin Diseases ◽  
Unknown Origin ◽  
The Elderly ◽  
Common Symptom ◽  
Multiple Factors ◽  
Signaling Mechanisms ◽  
Novel Drugs ◽  
Neuropathic Pruritus ◽  
Chronic Pruritus

Pruritus is a relatively common symptom that anyone can experience at any point in their life and is more common in the elderly. Pruritus in elderly can be defined as chronic pruritus in a person over 65 years old. The pathophysiology of pruritus in elderly is still unclear, and the quality of life is reduced. Generally, itch can be clinically classified into six types: Itch caused by systemic diseases, itch caused by skin diseases, neuropathic pruritus, psychogenic pruritus, pruritus with multiple factors, and from unknown causes. Senile pruritus can be defined as a chronic pruritus of unknown origin in elderly people. Various neuronal mediators, signaling mechanisms at neuronal terminals, central and peripheral neurotransmission pathways, and neuronal sensitizations are included in the processes causing itch. A variety of therapies are used and several novel drugs are being developed to relieve itch, including systemic and topical treatments.

Treatment of Refractory Chronic Pruritus of Unknown Origin With Tofacitinib in Patients With Rheumatoid Arthritis

2019 ◽  
Vol 155 (12) ◽  
pp. 1426 ◽  
Author(s):  
Fang Wang ◽  
Caroline Morris ◽  
Nancy D. Bodet ◽  
Brian S. Kim
Keyword(s):  
Rheumatoid Arthritis ◽  
Unknown Origin ◽  
Chronic Pruritus

scholarly journals Treatment of patients with chronic pruritus of unknown origin with dupilumab

2021 ◽  
pp. 1-4
Author(s):  
Jiehyun Jeon ◽  
Fang Wang ◽  
Asima Badic ◽  
Brian S. Kim
Keyword(s):  
Unknown Origin ◽  
Chronic Pruritus

scholarly journals Lactase Deficiency: A Potential Novel Aetiological Factor in Chronic Pruritus of Unknown Origin

2011 ◽  
Vol 91 (6) ◽  
pp. 698-703 ◽  
Author(s):  
S Grundmann ◽  
E Stratmann ◽  
R Brehler ◽  
T Luger ◽  
S Ständer
Keyword(s):  
Unknown Origin ◽  
Aetiological Factor ◽  
Lactase Deficiency ◽  
Chronic Pruritus
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