What are the effects of non-steroidal anti-inflammatory drugs used to prevent macular edema after cataract surgery?

2017 ◽  
Keyword(s):  
Cataract Surgery ◽  
Macular Edema ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Perioperative Topical Nonsteroidal Anti-inflammatory Drugs for Macular Edema Prophylaxis Following Cataract Surgery

2017 ◽  
Vol 176 ◽  
pp. 174-182 ◽  
Author(s):  
Bobeck S. Modjtahedi ◽  
John F. Paschal ◽  
Michael Batech ◽  
Tiffany Q. Luong ◽  
Donald S. Fong
Keyword(s):  
Cataract Surgery ◽  
Macular Edema ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

scholarly journals Comparison of the Efficacy and Safety of Non-Steroidal Anti-Inflammatory Drugs and Corticosteroid Drugs for Prevention of Cystoid Macular Edema After Cataract Surgery: A Systematic Review and Network Meta-Analysis

2021 ◽  
Author(s):  
Shanshan Li ◽  
Hui-Hui Wang ◽  
Da-Wei Zhang
Keyword(s):  
Cataract Surgery ◽  
Macular Edema ◽  
Cystoid Macular Edema ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Efficacy And Safety ◽  
Randomized Controlled ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Corticosteroid Drugs

Abstract Introduction: To compare the efficacy and safety of non-steroidal anti-inflammatory drugs (NSAID), corticosteroid (CS), and a combination of both drugs to prevent cystoid macular edema (CME) after cataract surgery. Methods We searched Pubmed, Cochrane Library, and Embase electronic databases to assess the relevant randomized controlled trials (RCTs) up to 28 April 2021. Network meta-analysis was registered on PROSPERO (CRD42020182520). Results Twenty-four RCTs were included in this review. The NSAID and combination of both drugs were significantly reduced the risk of developing CME than CS alone in non-diabetics and mix population. In the ranking profiles, the combination therapy showed a significant advantage over the single drugs and was less likely to develop CME. Diclofenac was the most likely to reduce the odds of developing CME compared with bromfenac and nepafenac. Dexamethasone was the most likely to reduce the odds of developing CME compared with betamethasone and fluorometholone. Conclusion NSAID combination with CS has significantly reduced the risk of developing CME postoperatively than the single drug. Diclofenac was superior to bromfenac and nepafenac in preventing CME. Dexamethasone was superior to betamethasone and fluorometholone in preventing CME.

Topical nonsteroidal anti-inflammatory drugs as adjuvant therapy in the prevention of macular edema after cataract surgery

2016 ◽  
Vol 37 (5) ◽  
pp. 1127-1131
Author(s):  
Nicola Cardascia ◽  
Carmela Palmisano ◽  
Tersa Centoducati ◽  
Giovanni Alessio
Keyword(s):  
Adjuvant Therapy ◽  
Cataract Surgery ◽  
Macular Edema ◽  
Inflammatory Drugs ◽  
Anti Inflammatory
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