Differentiation of mouse induced pluripotent stem cells into corneal epithelial-like cells

2012 ◽  
Vol 37 (1) ◽  
pp. 87-94 ◽  
Author(s):  
Dan Yu ◽  
Mengfei Chen ◽  
Xuerong Sun ◽  
Jian Ge
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Corneal Epithelial ◽  
Induced Pluripotent

P82. Differentiation of induced pluripotent stem cells into corneal epithelial cells

2010 ◽  
Vol 80 ◽  
pp. S44-S45
Author(s):  
S. Yoshida ◽  
M. Yasuda ◽  
M. Miyashita ◽  
Y. Tetsu ◽  
K. Tsubota ◽  
...  
Keyword(s):  
Stem Cells ◽  
Epithelial Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Corneal Epithelial Cells ◽  
Corneal Epithelial ◽  
Induced Pluripotent

scholarly journals Induced Pluripotent Stem Cells: Development in the Ophthalmologic Field

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Nan Wu ◽  
Marianne Doorenbos ◽  
Dong Feng Chen
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Disease Modeling ◽  
Ganglion Cells ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Great Promise ◽  
Corneal Epithelial ◽  
Induced Pluripotent

Human induced pluripotent stem cells (iPSCs) are a type of stem cells that can be derived from human somatic cells by introducing certain transcription factors. Induced pluripotent stem cells can divide indefinitely and are able to differentiate into every cell type, which make them viable for transplantation and individual disease modeling. Recently, various ocular cells, including corneal epithelial-like cells, retinal pigment epithelium (RPE) cells displaying functions similar to native RPE, photoreceptors, and retinal ganglion cells, have all been successfully derived from iPSCs. Transplantation of these cells in animal models showed great promise for reversing blindness, and the first clinical trial on humans started in 2013. Despite these promising results, more research is in demand for preventing inadvertent tumor growth, developing precise functionality of the cells, and promoting integration into the host tissue.

Directed differentiation of mouse-induced pluripotent stem cells generates dopaminergic nerve

2010 ◽  
Vol 34 (8) ◽  
pp. S36-S36
Author(s):  
Ping Duan ◽  
Xuelin Ren ◽  
Wenhai Yan ◽  
Xuefei Han ◽  
Xu Yan ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Directed Differentiation ◽  
Induced Pluripotent
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