Novel quinic acid glycerates from Tussilago farfara inhibit polypeptide GalNAc‐transferase

ChemBioChem ◽  
2021 ◽  
Author(s):  
Juan Feng ◽  
Yu-Peng Li ◽  
Youtian Hu ◽  
Yueyang Zhou ◽  
Hua Zhang ◽  
...  
Keyword(s):  
Quinic Acid ◽  
Tussilago Farfara

Isolation and Identification of β-Glucogallin, Coumaroyl Quinic Acid Derivative, and Flavonol Triglycosides as Antioxidants from Green Tea

2020 ◽  
Vol 26 (2) ◽  
pp. 57-65
Author(s):  
Eu-Jin Ban ◽  
Ju-Hyung Kim ◽  
So-Jin Lee ◽  
Dong-Jun Lee ◽  
Jae-Hak Moon ◽  
...  
Keyword(s):  
Green Tea ◽  
Acid Derivative ◽  
Quinic Acid ◽  
Isolation And Identification

scholarly journals Phytochemical Profiling of Methanolic Fruit Extract of Gardenia latifolia Ait. by LC-MS/MS Analysis and Evaluation of Its Antioxidant and Antimicrobial Activity

Plants ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 545
Author(s):  
Y. Mohan Reddy ◽  
S. P. Jeevan Kumar ◽  
K. V. Saritha ◽  
P. Gopal ◽  
T. Madhusudana Reddy ◽  
...  
Keyword(s):  
Quinic Acid ◽  
Differential Pulse ◽  
Deciduous Tree ◽  
Food Industries ◽  
Analysis And Evaluation ◽  
Southern States ◽  
Ms Analysis ◽  
Antioxidant And Antimicrobial Activity ◽  
Microtiter Assay ◽  
Caffeoyl Quinic Acid

Gardenia latifolia Ait. (Rubiaceae) is also known as Indian Boxwood is a small deciduous tree often growing in southern states of India. In the present study, phytochemical profiling of methanolic extract of G. latifolia fruits were carried out using FTIR and LC-MS/MS analysis. Besides, its antioxidant and antimicrobial potential have been analysed using DPPH activity, differential pulse voltammetry and resazurin microtiter assay, respectively. Phytochemical profiling revealed the presence of 22 major diversified compounds and main were 3-caffeoyl quinic acid (chlorogenic acid), 3,4-Di-O-caffeoyl quinic acid, 6-O-trans-feruloylgenipin gentiobioside, 10-(6-O-trans sinapoyl glucopyranosyl) gardendiol, isoquercitrin, scortechinones, secaubryenol, iridoids and quercetin 3-rutinoside (rutin). The extract showed antioxidant activity (IC50 = 65.82) and powerful antibacterial activity with lowest minimum inhibitory concentration against Gram-positive Staphylococcus aureus (15.62 µg/µL), Bacillus subtilis (31.25 µg/µL) than gram negative Escherichia coli (62.5 µg/µL), Klebsiella pneumoniae (62.5 µg/µL), Pseudomonas aeruginosa (31.25 µg/µL). This study shows that the fruits of G. latifolia have tremendous potential to be used in food industries, phyto-therapeutics and cosmetic industries.

scholarly journals Phytochemical Composition and Biological Activities of Scorzonera Species

2021 ◽  
Vol 22 (10) ◽  
pp. 5128
Author(s):  
Karolina Lendzion ◽  
Agnieszka Gornowicz ◽  
Krzysztof Bielawski ◽  
Anna Bielawska
Keyword(s):  
Biological Activities ◽  
Folk Medicine ◽  
Quinic Acid ◽  
Hepatoprotective Activity ◽  
Phytochemical Composition ◽  
Starting Point ◽  
Microbial Infections ◽  
Bacteria And Fungi ◽  
Bioactive Potential

The genus Scorzonera comprises nearly 200 species, naturally occurring in Europe, Asia, and northern parts of Africa. Plants belonging to the Scorzonera genus have been a significant part of folk medicine in Asia, especially China, Mongolia, and Turkey for centuries. Therefore, they have become the subject of research regarding their phytochemical composition and biological activity. The aim of this review is to present and assess the phytochemical composition, and bioactive potential of species within the genus Scorzonera. Studies have shown the presence of many bioactive compounds like triterpenoids, sesquiterpenoids, flavonoids, or caffeic acid and quinic acid derivatives in extracts obtained from aerial and subaerial parts of the plants. The antioxidant and cytotoxic properties have been evaluated, together with the mechanism of anti-inflammatory, analgesic, and hepatoprotective activity. Scorzonera species have also been investigated for their activity against several bacteria and fungi strains. Despite mild cytotoxicity against cancer cell lines in vitro, the bioactive properties in wound healing therapy and the treatment of microbial infections might, in perspective, be the starting point for the research on Scorzonera species as active agents in medical products designed for miscellaneous skin conditions.

Bioactive sesquiterpenoids from the flower buds of Tussilago farfara

2021 ◽  
pp. 104632
Author(s):  
Xiu-Qing Song ◽  
Jin-Hai Yu ◽  
Jia Sun ◽  
Kai-Lu Liu ◽  
Jun-Sheng Zhang ◽  
...  
Keyword(s):  
Flower Buds ◽  
Tussilago Farfara

scholarly journals Insight into the effect of quinic acid on biofilm formed byStaphylococcus aureus

RSC Advances ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. 3938-3945 ◽  
Author(s):  
Jin-Rong Bai ◽  
Yan-Ping Wu ◽  
Grosu Elena ◽  
Kai Zhong ◽  
Hong Gao
Keyword(s):  
Biofilm Formation ◽  
Quinic Acid ◽  
Biofilm Inhibition ◽  
Key Genes ◽  
Insight Into

QA effectively inhibitedS. aureusbiofilm formation. The key genes of biofilm inhibition induced by QA wereagrAandsarA.

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