Book Review: Biomimetic Materials and Design: Biointerfacial Strategies, Tissue Engineering, and Targeted Drug Delivery. Edited by Angela K. Dillow and Anthony M. Lowman

ChemBioChem ◽  
2003 ◽  
Vol 4 (11) ◽  
pp. 1250-1251 ◽  
Author(s):  
Andrew J. Putnam
Author(s):  
Manzoor A. Mir ◽  
Basharat A. Bhat ◽  
Bashir A. Sheikh ◽  
Gulzar Ahmed Rather ◽  
Safiya Mehraj ◽  
...  

The 21st century has seen a massive spring up in the applications of nanobiotechnology. Incorporation of functionalized and modified nanostructures in various biomedical applications has generated significant research interests such as implant and tissue engineering, diagnosis, and therapy, thereby aiding in improvement of human health. The unique properties of nanoparticles including non-toxicity and biocompatibility with a large surface area make it possible to modify their surface with different chemicals including different polymers, antibodies, and drug molecules. Therefore, they are utilized for targeted drug delivery in order to carry drugs and selectively release them in desired tissues which reduces destructive effects on healthy cells. This chapter mainly covers the basic properties of nanoparticles including nanomedicine, their preparation and focuses on their diagnosis, and therapeutic applications in disease including cancer and other challenging ailments.


2019 ◽  
Vol 25 (4) ◽  
pp. 424-443 ◽  
Author(s):  
Sabya S. Das ◽  
Neelam ◽  
Kashif Hussain ◽  
Sima Singh ◽  
Afzal Hussain ◽  
...  

Laponite based nanomaterials (LBNMs) are highly diverse regarding their mechanical, chemical, and structural properties, coupled with shape, size, mass, biodegradability and biocompatibility. These ubiquitous properties of LBNMs make them appropriate materials for extensive applications. These have enormous potential for effective and targeted drug delivery comprised of numerous biodegradable materials which results in enhanced bioavailability. Moreover, the clay material has been explored in tissue engineering and bioimaging for the diagnosis and treatment of various diseases. The material has been profoundly explored for minimized toxicity of nanomedicines. The present review compiled relevant and informative data to focus on the interactions of laponite nanoparticles and application in drug delivery, tissue engineering, imaging, cell adhesion and proliferation, and in biosensors. Eventually, concise conclusions are drawn concerning biomedical applications and identification of new promising research directions.


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