Walker 256 tumour growth causes marked changes of glutamine metabolism in rat small intestine

2002 ◽  
Vol 20 (2) ◽  
pp. 107-113 ◽  
Author(s):  
Manuela M. Ramos Lima ◽  
Maria Alice R. de Mello ◽  
Rui Curi
Keyword(s):  
Small Intestine ◽  
Tumour Growth ◽  
Glutamine Metabolism ◽  
Rat Small Intestine ◽  
Walker 256 Tumour ◽  
Walker 256

scholarly journals Moderate exercise training since adolescence reduces Walker 256 tumour growth in adult rats

2019 ◽  
Vol 597 (15) ◽  
pp. 3905-3925 ◽  
Author(s):  
Veridiana Mota Moreira ◽  
Douglas Almeida ◽  
Claudinéia Conationi da Silva Franco ◽  
Rodrigo Mello Gomes ◽  
Kesia Palma‐Rigo ◽  
...  
Keyword(s):  
Exercise Training ◽  
Tumour Growth ◽  
Moderate Exercise ◽  
Adult Rats ◽  
Walker 256 Tumour ◽  
Walker 256 ◽  
Moderate Exercise Training

Insulin treatment can abolish changes in glucose and glutamine metabolism of lymphocytes and macrophages caused by the implantation of the walker 256 tumour

1996 ◽  
Vol 14 (3) ◽  
pp. 187-192 ◽  
Author(s):  
Luiz Claudio Fernandes ◽  
Carlos Alberto Mattozo ◽  
Ubiratan Fabres Machado ◽  
Luis Fernando B. P. Costa Rosa ◽  
Rui Curi
Keyword(s):  
Insulin Treatment ◽  
Glutamine Metabolism ◽  
Walker 256 Tumour ◽  
Walker 256

Insulin Treatment Can Abolish Changes in Glucose and Glutamine Metabolism of Lymphocytes and Macrophages Caused by the Implantation of the Walker 256 Tumour

1996 ◽  
Vol 14 (3) ◽  
pp. 187-192 ◽  
Author(s):  
LUIZ CLAUDIO FERNANDES ◽  
CARLOS ALBERTO MATTOZO ◽  
UBIRATAN FABRES MACHADO ◽  
LUIS FERNANDO B. P. COSTA ROSA ◽  
RUI CURI
Keyword(s):  
Insulin Treatment ◽  
Glutamine Metabolism ◽  
Walker 256 Tumour ◽  
Walker 256

Effects of dexamethasone on glutamine metabolism in the isolated vascularly perfused rat small intestine

1991 ◽  
Vol 191 (1) ◽  
pp. 349-357 ◽  
Author(s):  
M. Plauth ◽  
A. Raible ◽  
D. Bauder-Groß ◽  
D. Vieillard-Baron ◽  
P. Fürst ◽  
...  
Keyword(s):  
Small Intestine ◽  
Glutamine Metabolism ◽  
Rat Small Intestine

scholarly journals Chronic Glibenclamide Treatment Attenuates Walker-256 Tumour Growth in Prediabetic Obese Rats

2017 ◽  
Vol 42 (1) ◽  
pp. 81-90 ◽  
Author(s):  
Claudinéia Conationi da Silva Franco ◽  
Carina Previate ◽  
Kátia Gama de Barros Machado ◽  
Silvano Piovan ◽  
Rosiane Aparecida Miranda ◽  
...  
Keyword(s):  
Tumour Growth ◽  
Tumour Cells ◽  
Diabetic Patients ◽  
Adult Rats ◽  
Walker 256 Tumour ◽  
Tumour Growth Inhibition ◽  
Walker 256 ◽  
Growth Methods ◽  
Tumour Weight

Background/Aims: The sulphonylurea glibenclamide (Gli) is widely used in the treatment of type 2 diabetes. In addition to its antidiabetic effects, low incidences of certain types of cancer have been observed in Gli-treated diabetic patients. However, the mechanisms underlying this observation remain unclear. The aim of the present work was to evaluate whether obese adult rats that were chronically treated with an antidiabetic drug, glibenclamide, exhibit resistance to rodent breast carcinoma growth. Methods: Neonatal rats were treated with monosodium L-glutamate (MSG) to induce prediabetes. Control and MSG groups were treated with Gli (2 mg/kg body weight/day) from weaning to 100 days old. After Gli treatment, the control and MSG rats were grafted with Walker-256 tumour cells. After 14 days, grafted rats were euthanized, and tumour weight as well as glucose homeostasis were evaluated. Results: Treatment with Gli normalized tissue insulin sensitivity and glucose tolerance, suppressed fasting hyperinsulinaemia, reduced fat tissue accretion in MSG rats, and attenuated tumour growth by 27% in control and MSG rats. Conclusions: Gli treatment also resulted in a large reduction in the number of PCNA-positive tumour cells. Although treatment did improve the metabolism of pre-diabetic MSG-rats, tumour growth inhibition may be a more direct effect of glibenclamide.

In situ demonstration of migration of dendritic cells released from rat small intestine to mesenteric lymph nodes

2001 ◽  
Vol 120 (5) ◽  
pp. A183-A183
Author(s):  
H KOBAYASHI ◽  
H NAGATA ◽  
S MIURA ◽  
T AZUMA ◽  
H SUZUKI ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Small Intestine ◽  
Lymph Nodes ◽  
Rat Small Intestine ◽  
Mesenteric Lymph Nodes ◽  
Mesenteric Lymph

Anti-inflammatory effect of STW 5, STW 6 and isolated extracts on the rat small intestine

2008 ◽  
Vol 29 (S 1) ◽  
Author(s):  
K Nieber ◽  
S Michael ◽  
K Grötzinger ◽  
JW Rauwald ◽  
O Kelber
Keyword(s):  
Small Intestine ◽  
Rat Small Intestine ◽  
Anti Inflammatory ◽  
Inflammatory Effect

Oral vanadate reduces Na(+)-dependent glucose transport in rat small intestine

Diabetes ◽  
1993 ◽  
Vol 42 (8) ◽  
pp. 1126-1132 ◽  
Author(s):  
K. L. Madsen ◽  
V. M. Porter ◽  
R. N. Fedorak
Keyword(s):  
Small Intestine ◽  
Glucose Transport ◽  
Rat Small Intestine
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