Halogenated Briarane Diterpenes with Acetyl Migration from the Gorgonian Coral Junceella fragilis

2017 ◽  
Vol 14 (5) ◽  
pp. e1700053 ◽  
Author(s):  
Wei Cheng ◽  
Xiaodan Li ◽  
Fuling Yin ◽  
Leen van Ofwegen ◽  
Wenhan Lin
2020 ◽  
Vol 4 (2) ◽  
pp. 16-24
Author(s):  
Nermeen Abdul Kader ◽  
Eman Habib ◽  
Hashem Hasanean ◽  
safwat ahmed ◽  
Reda Abdelhameed ◽  
...  
Keyword(s):  
Red Sea ◽  

2014 ◽  
Vol 4 (1) ◽  
Author(s):  
Hideyuki Yamashiro ◽  
Naoko Isomura ◽  
Kazuhiko Sakai
Keyword(s):  

2016 ◽  
Vol 17 (1) ◽  
pp. 79 ◽  
Author(s):  
Yin-Di Su ◽  
Chun-Sung Sung ◽  
Zhi-Hong Wen ◽  
Yu-Hsin Chen ◽  
Yu-Chia Chang ◽  
...  
Keyword(s):  

1984 ◽  
Vol 221 (2) ◽  
pp. 459-464 ◽  
Author(s):  
R E Isaac ◽  
H H Rees

Maturing eggs of the desert locust, Schistocerca gregaria, contain a variety of ecdysteroid (insect moulting hormone) conjugates and metabolites, four of which have been previously isolated from polar extracts and identified as ecdysonoic acid, 20-hydroxyecdysonoic acid, 3-acetylecdysone 2-phosphate and ecdysone 2-phosphate. In the present study we have isolated eight additional ecdysteroids from similar late-stage eggs by high-performance liquid chromatography. The 22-phosphate esters of ecdysone, 2-deoxyecdysone, 20-hydroxyecdysone and 2-deoxy-20-hydroxyecdysone, all of which were first identified as ecdysteroid components of newly-laid eggs of S. gregaria, were identified by co-chromatography with authentic compounds and by physicochemical techniques. The remaining compounds were identified as 3-acetyl-20-hydroxyecdysone 2-phosphate, 3-epi-2-deoxyecdysone 3-phosphate, 3-acetylecdysone 22-phosphate and 2-acetylecdysone 22-phosphate by fast atom bombardment mass spectrometry, p.m.r. spectroscopy and analysis of the steroid moieties after enzymic hydrolysis. The latter two compounds, after isolation, are susceptible to nonenzymic acetyl migration and deacetylation to give mixtures of ecdysone 22-phosphate and its 2- and 3-acetate derivatives. The possible role and significance of these ecdysteroid conjugates with respect to the control of hormone titres in insect eggs is discussed.


2013 ◽  
Vol 8 (8) ◽  
pp. 1934578X1300800 ◽  
Author(s):  
Hsu-Ming Chung ◽  
Wei-Hsien Wang ◽  
Tsong-Long Hwang ◽  
Yang-Chang Wu ◽  
Ping-Jyun Sung

Three natural clovane-related sesquiterpenoids, 2β-acetoxyclovan-9α-ol (1), 9α-acetoxyclovan-2β-ol (2) and clovan-2β,9β-diol (3), were isolated from the gorgonian coral Rumphella antipathies. The structures of clovanes 1–3 were elucidated by spectroscopic methods and by comparison of the spectral data with those of known clovane analogues. This is the first time that clovanes 1–3 have been isolated from a natural source. Clovanes 1 and 2 displayed inhibitory effects on the generation of superoxide anions and the release of elastase by human neutrophils.


2016 ◽  
Vol 11 (6) ◽  
pp. 1934578X1601100
Author(s):  
Hsin-Huan Chang ◽  
Yu-Chia Chang ◽  
Wu-Fu Chen ◽  
Tsong-Long Hwang ◽  
Lee-Shing Fang ◽  
...  

The structures of pubinernoid A (1) and apo-9′-fucoxanthinone (2), isolated from a gorgonian coral Pinnigorgia sp., were elucidated on the basis of spectroscopic analysis and by comparison of their spectroscopic data with those of known compounds. This is the first report of 1 and 2 from an animal source. Apo-9′-fucoxanthinone (2) displayed a significant inhibitory effect on the release of elastase by human neutrophils, with an IC50 value of 5.75 μM.


2020 ◽  
Vol 105 ◽  
pp. 104423
Author(s):  
Jiru Wu ◽  
Xiaodan Li ◽  
Xingchen Guo ◽  
Zhongbin Cheng ◽  
Junjun Meng ◽  
...  
Keyword(s):  

2010 ◽  
Vol 157 (5) ◽  
pp. 1003-1010 ◽  
Author(s):  
Nini Johanna Cadena ◽  
Camilo Rey ◽  
Marcela Hernández-Hoyos ◽  
J. Darío Sánchez ◽  
Stanislas Teillaud ◽  
...  

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