Synthesis of a Natural Chalcone and Its Prenyl Analogs - Evaluation of Tumor Cell Growth-Inhibitory Activities, and Effects on Cell Cycle and Apoptosis

2012 ◽  
Vol 9 (6) ◽  
pp. 1133-1143 ◽  
Author(s):  
Marta P. Neves ◽  
Raquel T. Lima ◽  
Kanthima Choosang ◽  
Panee Pakkong ◽  
Maria de São José Nascimento ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cell Growth ◽  
Tumor Cell ◽  
Tumor Cell Growth ◽  
Growth Inhibitory ◽  
Inhibitory Activities

Farnesyl protein transferase and tumor cell growth inhibitory activities of lipiferolide isolated fromLiriodendron tulipifera

2007 ◽  
Vol 30 (3) ◽  
pp. 299-302 ◽  
Author(s):  
Mi Kyeong Moon ◽  
Hyun Mi Oh ◽  
Byoung-Mog Kwon ◽  
Nam-ln Baek ◽  
Sung-Hoon Kim ◽  
...  
Keyword(s):  
Cell Growth ◽  
Tumor Cell ◽  
Tumor Cell Growth ◽  
Growth Inhibitory ◽  
Farnesyl Protein Transferase ◽  
Inhibitory Activities

scholarly journals Synthesis and Bioevaluation of Thieno[2,3-d]pyrimidinone Derivatives as Potential Tumor Cell Growth Inhibitors

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Huangyong Li ◽  
Changshui Chen ◽  
Shengzhen Xu ◽  
Xiufang Cao
Keyword(s):  
Cell Growth ◽  
Tumor Cell ◽  
Bioactive Molecules ◽  
Tumor Cell Growth ◽  
Growth Inhibitors ◽  
Growth Inhibitory ◽  
Growth Inhibitory Activity ◽  
Inhibitory Activities ◽  
Alkylation Reactions ◽  
Mcf 7

A series of novel cycloalkylthieno[2,3-d]pyrimidinone derivatives have been conveniently synthesizedviathree steps including G-3CR, heterocyclization, and alkylation reactions as a part of our ongoing search for new bioactive molecules. The newly synthesized compounds were evaluated for their potential tumor cell growth inhibitory activity by standard MTT assay. The preliminary results show that compound6bexhibited better inhibitory activities against HepG2, MCF-7, and BCG-823 cell lines compared to the control.

scholarly journals Synthesis and Evaluation of the Tumor Cell Growth Inhibitory Potential of New Putative HSP90 Inhibitors

Molecules ◽  
2018 ◽  
Vol 23 (2) ◽  
pp. 407 ◽  
Author(s):  
Ana Bizarro ◽  
Diana Sousa ◽  
Raquel Lima ◽  
Loana Musso ◽  
Raffaella Cincinelli ◽  
...  
Keyword(s):  
Cell Growth ◽  
Tumor Cell ◽  
Tumor Cell Growth ◽  
Hsp90 Inhibitors ◽  
Growth Inhibitory ◽  
Inhibitory Potential

Inhibition of tumor cell growth by triton X-100 through specific effects on cell-cycle-regulatory components

2004 ◽  
Vol 11 (1) ◽  
pp. 95-103 ◽  
Author(s):  
Esther R. Picache ◽  
Loubna Hassanieh ◽  
Daniel Broek ◽  
Axel H. Schönthal
Keyword(s):  
Cell Cycle ◽  
Cell Growth ◽  
Tumor Cell ◽  
Tumor Cell Growth ◽  
Specific Effects ◽  
Triton X

scholarly journals Inhibition of tumor cell growth by adenine is mediated by apoptosis induction and cell cycle S phase arrest

Oncotarget ◽  
2017 ◽  
Vol 8 (55) ◽  
pp. 94286-94296 ◽  
Author(s):  
Ming Han ◽  
Xin Cheng ◽  
Zhiqin Gao ◽  
Rongrong Zhao ◽  
Shizhuang Zhang
Keyword(s):  
Cell Cycle ◽  
Cell Growth ◽  
Tumor Cell ◽  
S Phase ◽  
Tumor Cell Growth ◽  
Apoptosis Induction ◽  
Phase Arrest ◽  
S Phase Arrest

scholarly journals Synthesis and Tumor Cell Growth Inhibitory Effects of New Flavonosides and Xanthonosides

2017 ◽  
Author(s):  
Emília Sousa ◽  
Ana Rita Neves ◽  
Marta Correia-da-Silva ◽  
Patrícia M.A. Silva ◽  
Diana Ribeiro ◽  
...  
Keyword(s):  
Cell Growth ◽  
Tumor Cell ◽  
Tumor Cell Growth ◽  
Inhibitory Effects ◽  
Growth Inhibitory
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