scholarly journals A clinical trial to compare a 3D‐printed bolus with a conventional bolus with the aim of reducing cardiopulmonary exposure in postmastectomy patients with volumetric modulated arc therapy

2021 ◽  
Author(s):  
Yun Zhang ◽  
Yuling Huang ◽  
Shenggou Ding ◽  
Jinghui Liang ◽  
Jie Kuang ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Volumetric Modulated Arc Therapy ◽  
Arc Therapy ◽  
3D Printed

Quality assurance of volumetric modulated arc therapy using Elekta Synergy

2009 ◽  
pp. 1-5 ◽  
Author(s):  
Akihiro Haga ◽  
Keiichi Nakagawa ◽  
Kenshiro Shiraishi ◽  
Saori Itoh ◽  
Atsuro Terahara ◽  
...  
Keyword(s):  
Quality Assurance ◽  
Volumetric Modulated Arc Therapy ◽  
Arc Therapy

scholarly journals Physical dosimetry of volumetric modulated arc therapy (VMAT) using EPID and 2D array for quality assurance

2018 ◽  
Vol 49 (2) ◽  
pp. 477-484
Author(s):  
Ismail E. Mohamed ◽  
Ayman G. Ibrahim ◽  
Hamdy M. Zidan ◽  
Hesham S. El-Bahkiry ◽  
Adel Y. El-sahragti
Keyword(s):  
Quality Assurance ◽  
Volumetric Modulated Arc Therapy ◽  
Arc Therapy ◽  
2D Array

scholarly journals Personalised high tibial osteotomy has mechanical safety equivalent to generic device in a case–control in silico clinical trial

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Alisdair R. MacLeod ◽  
Nicholas Peckham ◽  
Gil Serrancolí ◽  
Ines Rombach ◽  
Patrick Hourigan ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Relative Risk ◽  
Knee Osteoarthritis ◽  
High Tibial Osteotomy ◽  
Fatigue Failure ◽  
In Silico ◽  
Odds Ratio ◽  
Case Control ◽  
Tibial Osteotomy ◽  
3D Printed

Abstract Background Despite favourable outcomes relatively few surgeons offer high tibial osteotomy (HTO) as a treatment option for early knee osteoarthritis, mainly due to the difficulty of achieving planned correction and reported soft tissue irritation around the plate used to stablise the osteotomy. To compare the mechanical safety of a new personalised 3D printed high tibial osteotomy (HTO) device, created to overcome these issues, with an existing generic device, a case-control in silico virtual clinical trial was conducted. Methods Twenty-eight knee osteoarthritis patients underwent computed tomography (CT) scanning to create a virtual cohort; the cohort was duplicated to form two arms, Generic and Personalised, on which virtual HTO was performed. Finite element analysis was performed to calculate the stresses in the plates arising from simulated physiological activities at three healing stages. The odds ratio indicative of the relative risk of fatigue failure of the HTO plates between the personalised and generic arms was obtained from a multi-level logistic model. Results Here we show, at 12 weeks post-surgery, the odds ratio indicative of the relative risk of fatigue failure was 0.14 (95%CI 0.01 to 2.73, p = 0.20). Conclusions This novel (to the best of our knowledge) in silico trial, comparing the mechanical safety of a new personalised 3D printed high tibial osteotomy device with an existing generic device, shows that there is no increased risk of failure for the new personalised design compared to the existing generic commonly used device. Personalised high tibial osteotomy can overcome the main technical barriers for this type of surgery, our findings support the case for using this technology for treating early knee osteoarthritis.

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