Purification of resveratrol, arachidin-1, and arachidin-3 from hairy root cultures of peanut (Arachis hypogaea) and determination of their antioxidant activity and cytotoxicity

2010 ◽  
Vol 26 (5) ◽  
pp. 1344-1351 ◽  
Author(s):  
Julie A. Abbott ◽  
Fabricio Medina-Bolivar ◽  
Elizabeth M. Martin ◽  
Abigail S. Engelberth ◽  
Hector Villagarcia ◽  
...  
2013 ◽  
Vol 61 (48) ◽  
pp. 11744-11758 ◽  
Author(s):  
Cesar Nopo-Olazabal ◽  
John Hubstenberger ◽  
Luis Nopo-Olazabal ◽  
Fabricio Medina-Bolivar

2020 ◽  
Vol 56 (1) ◽  
pp. 8-17 ◽  
Author(s):  
Gladis J Solis-Castañeda ◽  
Alejandro Zamilpa ◽  
Emmanuel Cabañas-García ◽  
Silvia Marquina Bahena ◽  
Eugenio Pérez-Molphe-Balch ◽  
...  

Molecules ◽  
2020 ◽  
Vol 25 (3) ◽  
pp. 509 ◽  
Author(s):  
Lingling Fang ◽  
Tianhong Yang ◽  
Fabricio Medina-Bolivar

Prenylated stilbenoids are phenolic compounds produced in a small number of plants such as peanut (Arachis hypogaea) to counteract biotic and abiotic stresses. In addition to their role in plant defense, they exhibit biological activities with potential application in human health. Whereas non-prenylated stilbenoids such as resveratrol are commercially available, the availability of prenylated stilbenoids is limited. To this end, hairy root cultures of peanut were developed as an elicitor-controlled bioproduction platform for prenylated stilbenoids. An orthogonal array design approach led to the elucidation of an optimized elicitation procedure consisting of co-treatment of the hairy root cultures with 18 g/L methyl-β-cyclodextrin, 125 µM methyl jasmonate, 3 mM hydrogen peroxide (H2O2) and medium supplementation with additional 1 mM magnesium chloride. After 168-h of elicitor treatment, the combined yield of the prenylated stilbenoids arachidin-1, arachidin-2, arachidin-3 and arachidin-5 reached approximately 750 mg/L (equivalent to 107 mg/g DW). Moreover, hairy root cultures from the wild Arachis species A. duranensis and A. ipaensis were developed and shown to produce prenylated stilbenoids upon elicitor treatment. These wild Arachis hairy root lines may provide a platform to elucidate the biosynthetic origin of prenylated stilbenoids in peanut.


2014 ◽  
Vol 118 (3) ◽  
pp. 545-557 ◽  
Author(s):  
Muthu Thiruvengadam ◽  
Nagella Praveen ◽  
K. M. Maria John ◽  
Ye-Sul Yang ◽  
Seung-Hyun Kim ◽  
...  

2010 ◽  
Vol 65 (2) ◽  
pp. 105-111 ◽  
Author(s):  
Vasil Georgiev Georgiev ◽  
Jost Weber ◽  
Eva-Maria Kneschke ◽  
Petko Nedyalkov Denev ◽  
Thomas Bley ◽  
...  

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