scholarly journals Stress reactivity and pain-mediated stress regulation in remitted patients with borderline personality disorder

2018 ◽  
Vol 8 (2) ◽  
pp. e00909 ◽  
Author(s):  
Franziska Willis ◽  
Sarah Kuniss ◽  
Nikolaus Kleindienst ◽  
Stefanie Lis ◽  
Janina Naoum ◽  
...  
2017 ◽  
Vol 8 ◽  
Author(s):  
Nadège Bourvis ◽  
Aveline Aouidad ◽  
Clémence Cabelguen ◽  
David Cohen ◽  
Jean Xavier

2020 ◽  
pp. 1-8
Author(s):  
Timothy A. Allen ◽  
Alexandre Y. Dombrovski ◽  
Paul H. Soloff ◽  
Michael N. Hallquist

Abstract Background Individuals diagnosed with borderline personality disorder (BPD) often describe their lives as stressful and unpredictable. However, it is unclear whether the adversity faced by those with BPD is a product of stress reactivity or stress generation. Here, we examined the dynamic, prospective associations between BPD and stressful life events over 3 years. Given the heterogeneity present in BPD, we sought to understand which empirically derived dimensions of this heterogeneous disorder explain stress reactivity v. stress generation. Methods Participants included 355 individuals diagnosed with BPD and followed longitudinally at three annual assessments. Auto-regressive cross-lagged panel models were used to examine prospective associations between stressful life events and three latent dimensions implicated in BPD: negative affect, disinhibition, and antagonism. Results Antagonism and disinhibition, but not negative affect, prospectively predicted dependent stressful life events (events the individual may have some role in). Evidence for decompensation under stress was more tenuous, with independent stressful life events (those presumably outside the individual's control) predicting increases in negative affect. Conclusions Our longitudinal study of a well-characterized clinical sample found more evidence for stress generation than for stress-induced decompensation in BPD. Stress generation in BPD is driven by externalizing dimensions: antagonism and disinhibition. These results highlight the utility of empirically derived dimensions for parsing heterogeneity present in BPD, leading to improvements in diagnostic evaluation, clinical prediction, and individualized approaches to treatment planning.


2012 ◽  
pp. 605-615 ◽  
Author(s):  
Sarah Reitz ◽  
Annegret Krause-Utz ◽  
Esther M. Pogatzki-Zahn ◽  
Ulrich Ebner-Priemer ◽  
Martin Bohus ◽  
...  

2011 ◽  
Vol 36 (9) ◽  
pp. 1418-1421 ◽  
Author(s):  
D. Simeon ◽  
J. Bartz ◽  
H. Hamilton ◽  
S. Crystal ◽  
A. Braun ◽  
...  

2007 ◽  
Vol 38 (9) ◽  
pp. 1231-1239 ◽  
Author(s):  
J.-P. Glaser ◽  
J. Van Os ◽  
R. Mengelers ◽  
I. Myin-Germeys

SUMMARYBackgroundStress is postulated to play an essential role in the expression of core borderline symptoms. However, the phenomenology of stress reactivity in borderline personality disorder remains unclear. The current study investigated the phenomenology of stress sensitivity in borderline personality disorder in the flow of daily life and compared this with stress sensitivity in patients suffering from psychotic disorders, a group so far known to report the largest reactivity to stress.MethodA total of 44 borderline patients, 42 patients with psychotic disorder and 49 healthy controls were studied with the Experience Sampling Method (a structured diary technique assessing current context and mood in daily life) to assess: (1) appraised subjective stress related to daily events and activities; and (2) emotional reactivity conceptualized as changes in positive and negative affect.ResultsMultilevel regression analysis revealed that subjects with borderline personality disorder experienced significantly more emotional reactivity to daily life stress compared with both patients with psychosis and healthy controls, as evidenced by a larger increase in negative affect and a larger decrease in positive affect following stress.ConclusionThese results are the first to ecologically validate the incorporation of stress reactive symptoms in the diagnosis of borderline personality disorder. Borderline patients continually react stronger than patients with psychosis and healthy controls to small disturbances that continually happen in the natural flow of everyday life. Altered emotional stress reactivity may define borderline personality disorder.


Pain ◽  
2017 ◽  
Vol 158 (3) ◽  
pp. 479-487 ◽  
Author(s):  
Franziska Willis ◽  
Sarah Kuniss ◽  
Nikolaus Kleindienst ◽  
Janina Naoum ◽  
Sarah Reitz ◽  
...  

2020 ◽  
Author(s):  
Timothy Allen

Background: Individuals diagnosed with borderline personality disorder (BPD) often describe their lives as stressful and unpredictable. However, it is unclear whether the adversity faced by those with BPD is a product of stress reactivity or stress generation. Here, we examined the dynamic, prospective associations between BPD and stressful life events over three years. Given the heterogeneity present in BPD, we sought to understand which empirically derived dimensions of this heterogenous disorder explain stress reactivity vs. stress generation.Methods: Participants included 355 individuals diagnosed with BPD and followed longitudinally at three annual assessments. Auto-regressive cross-lagged panel models were used to examine prospective associations between stressful life events and three latent dimensions implicated in BPD: negative affect, disinhibition, and antagonism. Results: Antagonism and disinhibition, but not negative affect, prospectively predicted dependent stressful life events (events the individual may have some role in). Evidence for decompensation under stress was more tenuous, with independent stressful life events (those presumably outside the individual’s control) predicting increases in negative affect.Conclusions: Our longitudinal study of a well-characterized clinical sample found more evidence for stress generation than for stress-induced decompensation in BPD. Stress generation in BPD is driven by externalizing dimensions: antagonism and disinhibition. These results highlight the utility of empirically derived dimensions for parsing heterogeneity present in BPD, leading to improvements in diagnostic evaluation, clinical prediction, and individualized approaches to treatment planning.


2012 ◽  
Vol 26 (4) ◽  
pp. 605-615 ◽  
Author(s):  
Sarah Reitz ◽  
Annegret Krause-Utz ◽  
Esther M. Pogatzki-Zahn ◽  
Ulrich Ebner-Priemer ◽  
Martin Bohus ◽  
...  

2008 ◽  
Vol 23 (3) ◽  
pp. 201-204 ◽  
Author(s):  
Marc Walter ◽  
Jean-François Bureau ◽  
Bjarne M. Holmes ◽  
Eszter A. Bertha ◽  
Michael Hollander ◽  
...  

AbstractHypothalamic–pituitary–adrenal axis dysregulation after stress was found to be associated with borderline personality disorder (BPD). Nine female BPD young adults and 12 control subjects were investigated for stress reactivity and recovery after an interpersonal conflict discussion with their mothers. BPD subjects showed a delayed cortisol response after psychosocial stress.


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