Development of fully automated quantitative capillary electrophoresis with high accuracy and repeatability

2015 ◽  
Vol 30 (3) ◽  
pp. 390-395 ◽  
Author(s):  
Yuan Xu ◽  
Bang-zan Ling ◽  
Wen-jun Zhu ◽  
Dong Yao ◽  
Lin Zhang ◽  
...  
Keyword(s):  
Capillary Electrophoresis ◽  
High Accuracy ◽  
Accuracy And Repeatability

scholarly journals Functional Design of a 6-DOF Platform for Micro-Positioning

Robotics ◽  
2020 ◽  
Vol 9 (4) ◽  
pp. 99
Author(s):  
Matteo-Claudio Palpacelli ◽  
Luca Carbonari ◽  
Giacomo Palmieri ◽  
Fabio D’Anca ◽  
Ettore Landini ◽  
...  
Keyword(s):  
Kinematic Model ◽  
High Accuracy ◽  
Functional Design ◽  
Spatial Motion ◽  
Precise Positioning ◽  
Singular Configurations ◽  
Physical Prototype ◽  
Parallel Kinematic ◽  
Parallel Platform ◽  
Accuracy And Repeatability

Parallel kinematic machines (PKMs) have demonstrated their potential in many applications when high stiffness and accuracy are needed, even at micro- and nanoscales. The present paper is focused on the functional design of a parallel platform providing high accuracy and repeatability in full spatial motion. The hexaglide architecture with 6-PSS kinematics was demonstrated as the best solution according to the specifications provided by an important Italian company active in the field of micro-positioning, particularly in vacuum applications. All the steps needed to prove the applicability of such kinematics at the microscale and their inherent advantages are presented. First, the kinematic model of the manipulator based on the study’s parametrization is provided. A global conditioning index (GCI) is proposed in order to optimize the kinetostatic performance of the robot, so that precise positioning in the required platform workspace is guaranteed avoiding singular configurations. Some numerical simulations demonstrate the effectiveness of the study. Finally, some details about the realization of a physical prototype are given.

Automatic Test System for the Basic Properties of Solar Cells

2012 ◽  
Vol 251 ◽  
pp. 26-30
Author(s):  
Jia Jia Tu ◽  
Guo Wei Liang
Keyword(s):  
Solar Cells ◽  
Real Time ◽  
Natural Environment ◽  
Environmental Conditions ◽  
High Accuracy ◽  
Test System ◽  
Automatic Test System ◽  
Basic Properties ◽  
Different Types ◽  
Accuracy And Repeatability

A solar cells test system that can be used in the natural environment is designed, which can complete a variety of test experiments on different types of solar cells under different environmental conditions. In the testing process, the basic properties of solar cells are given and recorded in real time. Since installed and operated, the system works stable. Experimental results show that the test system has high accuracy and repeatability, and in line with the requirements of solar cells testing.

Characterisation and Approval of FKM Polymers and Compounds with RPA – an Initial Experience Report

2018 ◽  
Vol 45 (4) ◽  
pp. 183-190
Author(s):  
J. Guntrum ◽  
G. Dinu-Biringer ◽  
T. Weber ◽  
J. Klein
Keyword(s):  
Viscoelastic Properties ◽  
High Strain ◽  
High Accuracy ◽  
Shop Floor ◽  
Suitable Alternative ◽  
Test Conditions ◽  
Rubber Compounds ◽  
Normal Test ◽  
Mooney Viscosity ◽  
Accuracy And Repeatability

For decades, measurement of the Mooney viscosity has been used for testing the viscosity of raw polymers and mixed stocks. The Mooney viscometer is commonly used on the shop floor alongside the rheometer. The relevance of the Mooney test for the processing of rubber compounds is limited and the use of a rubber process analyser (RPA) is a suitable alternative. The instrument is robust, easy to handle and therefore perfectly suitable for day-to-day use on the shop floor. High accuracy and repeatability of the measurement are further advantages. This article describes initial experiences with testing FKM raw polymers and compounds based on frequency and strain sweeps. Tests under high strain in particular demonstrate significant differences between polymers, which are not seen under normal test conditions (small amplitudes). In this way, rubber compounders and processors receive considerably more information about the viscoelastic properties of the raw polymers used and the compounds produced from them.

Poly-Articulated System with Spatial Positioning

2013 ◽  
Vol 371 ◽  
pp. 411-415
Author(s):  
Gheorghe Stan
Keyword(s):  
Control Systems ◽  
Closed Loop ◽  
High Accuracy ◽  
Modular Structure ◽  
Positioning Accuracy ◽  
Rotary Axes ◽  
Spatial Positioning ◽  
Short Time ◽  
And Control ◽  
Accuracy And Repeatability

Researchers in the field of robotics have intense preoccupations on building cheaper and faster robots, with higher accuracy and repeatability, with modulated architectures, diversified in terms of design and oriented to the most diverse activities. The present work is placed in this context; it presents a new poly-articulated system, brevetted, with availability for spatial positioning at high accuracy and repeatability. Thus the robot can insert its arm through windows of small size and place the arm behind a panel etc. The modular structure of its joints provides the possibility for obtaining several advantages on performing various configurations in a short time and on lower expenses. At the same time, the driving and control systems of the rotary axes are conceived in closed loop that confers the premises for obtaining a high positioning accuracy.

scholarly journals Elevated Polyamines in Saliva of Pancreatic Cancer

2018 ◽  
Author(s):  
Yasutsugu Asai ◽  
Takao Itoi ◽  
Masahiro Sugimoto ◽  
Atsushi Sofuni ◽  
Takayoshi Tsuchiya ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Pancreatic Cancer ◽  
Capillary Electrophoresis ◽  
Chronic Pancreatitis ◽  
Screening Test ◽  
High Accuracy ◽  
The Other ◽  
Non Invasive ◽  
Accurate Detection ◽  
Significant Difference

Detection of pancreatic cancer (PC) at a resectable stage is still difficult because of the lack of accurate detection tests. The development of accurate biomarkers in low or non-invasive biofluids is essential to enable frequent tests, which would help increase the opportunity of PC detection in early stages. Polyamines have been reported as possible biomarkers in urine and saliva samples in various cancers. Here, we analyzed salivary metabolites, including polyamines, using capillary electrophoresis-mass spectrometry. Salivary samples were collected from patients with PC (n=39), chronic pancreatitis (CP, n=14) and controls (C, n=26). Polyamines, such as spermine, N1-acetylspermidine, and N1-acetylspermine, showed a significant difference between PC and C, and the combination of four metabolites including N1-acetylspermidine showed high accuracy in discriminating PC from the other two groups. These data showed the potential of saliva as a screening test for PC.

Stochastic Evaluation and Analysis of Free Vibrations in Simply Supported Piezoelectric Bimorphs

2013 ◽  
Vol 80 (2) ◽  
Author(s):  
Alberto Borboni ◽  
Rodolfo Faglia
Keyword(s):  
Parameter Estimation ◽  
Natural Frequencies ◽  
High Accuracy ◽  
Free Vibrations ◽  
Piezoelectric Bimorph ◽  
Simply Supported ◽  
Piezoelectric Bimorphs ◽  
Accuracy And Repeatability ◽  
Piezoelectric Devices ◽  
External Reasons

Piezoelectric bimorph benders are a particular class of piezoelectric devices, which are characterized by the ability to produce flexural deformation greatly larger than the length or thickness deformation of a single piezoelectric layer. Due to extensive dimensional reduction of devices and to the high accuracy and repeatability requested, the effect of erroneous parameter estimation and the fluctuation of parameters due to external reasons, sometimes, cannot be omitted. As such, we consider mechanical, electrical and piezoelectric parameters as uniformly distributed around a nominal value and we calculate the distribution of natural frequencies of the device. We consider an analytical model for the piezoelectric bimorph proposed in literature. The results show how the parameters errors are reflected on the natural frequencies and how an increment of the error is able to change the shape of the frequencies distribution.

Positional Accuracy Based on a Load Identification Optimization on a Linear Motor Sheet Forming Feeder

2014 ◽  
Vol 680 ◽  
pp. 311-314
Author(s):  
Nazrul Idzham Kasim ◽  
Akhtar Razul Razali ◽  
Mohd Azam Musa
Keyword(s):  
High Speed ◽  
High Accuracy ◽  
Sheet Forming ◽  
Strip Thickness ◽  
Load Identification ◽  
Feeding Rates ◽  
Positional Accuracy ◽  
Multi Stage ◽  
Progressive Forming ◽  
Accuracy And Repeatability

Precision feeding is essential for micro-stamping, especially in multi-stage progressive forming operations, where necessary feeding rates also have to be maintained. Research in micro-stamping of thinner sheet metals (<100 microns) led to investigations of the performance of existing sheet-metal feeders, regarding their accuracy and repeatability in high speed micro-stamping. The results indicated that the pursuance of higher feeding accuracy and repeatability which aimed at 5-15% of the strip thickness was unachievable with the existing micro-feeders. A new high-precision and high-speed feeder was, therefore, developed for micro-sheet-forming. Initial non-optimized experimental results had showed high accuracy and repeatability were achieved.

scholarly journals Development of Surgical Tools and Procedures for Experimental Preclinical Surgery Using Computer Simulations And 3D Printing

2020 ◽  
Vol 16 (09) ◽  
pp. 183
Author(s):  
Jan Barcik ◽  
Manuela Ernst ◽  
Ronald Schwyn ◽  
Linda Freitag ◽  
Constantin Edmond Dlaska ◽  
...  
Keyword(s):  
Bone Fractures ◽  
High Accuracy ◽  
Iterative Refinement ◽  
Large Animal ◽  
Bone Fracture Healing ◽  
Large Animal Models ◽  
Final Design ◽  
Cutting Guides ◽  
Accuracy And Repeatability

<p class="0abstract"><strong>Abstract—</strong>Experimental preclinical surgeries require high accuracy and repeatability in all applied procedures. For <em>in vivo</em> studies investigating bone fracture healing it is crucial to create precisely and consistently the experimental bone fractures in all included subjects. In large animal models the required precision is usually achieved by application of dedicated drilling jigs and cutting guides that often need to be individually designed in order to fulfil the requirements of a particular experiment. Moreover, their final design may considerably differ from the prototypes. Hence, the designing and testing processes require multiple iterative refinement loops substantially increasing the costs of the experiment. Therefore, a framework for development of tailor-made instruments for experimental preclinical surgeries is established to reduce the investment of time and financial effort.</p>

Influence of the Dispenser Valve Design on the Efficiency of Analysis of Unstable Gas Condensate

2021 ◽  
Vol 627 (5) ◽  
pp. 39-44
Author(s):  
K. M. Mazurova ◽  
◽  
Yu. I. Dyakina ◽  
E. A. Chudin ◽  
A. V. Domovenko ◽  
...  
Keyword(s):  
High Pressure ◽  
High Temperature ◽  
Direct Injection ◽  
Analysis Data ◽  
High Accuracy ◽  
Gas Condensate ◽  
Regulatory Requirements ◽  
Valve Design ◽  
Sampling Device ◽  
Accuracy And Repeatability

When analyzing unstable gas condensate using direct sample injection into the chromatograph, the design features and operating parameters of the sampling device have a significant impact on the accuracy and repeatability of the analysis. In this work, the influence of the characteristics of two types of sampling devices was studied: a high-pressure sampler in a high-temperature design; a sampler with a syringe-free injector, on the efficiency of the analysis of unstable gas condensate (GSO 10525–2014) using the direct injection method. It was shown that the use of a high-pressure sampler in a high-temperature design allowed achieving high accuracy and repeatability of analysis (data correspond to STO Gazprom 5.5–2007). When using a standard sampler, a significant deviation from the regulatory requirements for hydrocarbons starting from C28 was observed.

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