Application of case study to introduce medical students to molecular biology techniques used in HIV diagnostics

2019 ◽  
Vol 47 (3) ◽  
pp. 355-360
Author(s):  
Kinga A. Kocemba‐Pilarczyk ◽  
Barbara Ostrowska ◽  
Paulina Dudzik ◽  
Michał J. Markiewicz ◽  
Débora Sotirios Souza Pegos ◽  
...  
2020 ◽  
Vol 54 (7) ◽  
pp. 643-651 ◽  
Author(s):  
Jonathan Foo ◽  
George Rivers ◽  
Louise Allen ◽  
Dragan Ilic ◽  
Stephen Maloney ◽  
...  

PLoS ONE ◽  
2018 ◽  
Vol 13 (3) ◽  
pp. e0194096 ◽  
Author(s):  
Alfredo Corell ◽  
Luisa M. Regueras ◽  
Elena Verdú ◽  
María J. Verdú ◽  
Juan P. de Castro

2018 ◽  
Vol 31 (2) ◽  
pp. 119-128 ◽  
Author(s):  
Charo Rodríguez ◽  
Emmanuelle Bélanger ◽  
Peter Nugus ◽  
Miriam Boillat ◽  
Marion Dove ◽  
...  

Genome ◽  
2020 ◽  
Author(s):  
Rachel M. Price ◽  
Marek A Budzynski ◽  
Shivani Kundra ◽  
Sheila S. Teves

At the heart of the transcription process is the specific interaction between transcription factors (TFs) and their target DNA sequences. Decades of molecular biology research have led to unprecedented insights into how TFs access the genome to regulate transcription. In the last 20 years, advances in microscopy have enabled scientists to add imaging as a powerful tool in probing two specific aspects of TF-DNA interactions: structure and dynamics. In this review, we examine how applications of diverse imaging technologies can provide structural and dynamic information that complements insights gained from molecular biology assays. As a case study, we discuss how applications of advanced imaging techniques have reshaped our understanding of TF behavior across the cell cycle, leading to a rethinking in the field of mitotic bookmarking.


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