Hydroxyl‐ and Halogen‐containing Chalcones for the Inhibition of LPS‐stimulated ROS Production in RAW 264.7 Macrophages: Design, Synthesis and Structure–Activity Relationship Study

Aarajana Shrestha; Aastha Shrestha; Pil‐Hoon Park; Eung‐Seok Lee

doi:10.1002/bkcs.11813

Hydroxyl‐ and Halogen‐containing Chalcones for the Inhibition of LPS‐stimulated ROS Production in RAW 264.7 Macrophages: Design, Synthesis and Structure–Activity Relationship Study

Bulletin of the Korean Chemical Society ◽

10.1002/bkcs.11813 ◽

2019 ◽

Vol 40 (7) ◽

pp. 729-734

Author(s):

Aarajana Shrestha ◽

Aastha Shrestha ◽

Pil‐Hoon Park ◽

Eung‐Seok Lee

Keyword(s):

Structure Activity Relationship ◽

Activity Relationship ◽

Raw 264.7 ◽

Ros Production ◽

Design Synthesis ◽

Raw 264.7 Macrophages ◽

Structure Activity ◽

Relationship Study

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Design, synthesis, and structure-activity relationship study of halogen containing 2-benzylidene-1-indanone derivatives for inhibition of LPS-stimulated ROS production in RAW 264.7 macrophages

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2017.03.049 ◽

2017 ◽

Vol 133 ◽

pp. 121-138 ◽

Cited By ~ 10

Author(s):

Aarajana Shrestha ◽

Hye Jin Oh ◽

Mi Jin Kim ◽

Nirmala Tilija Pun ◽

Til Bahadur Thapa Magar ◽

...

Keyword(s):

Structure Activity Relationship ◽

Activity Relationship ◽

Raw 264.7 ◽

Ros Production ◽

Design Synthesis ◽

Raw 264.7 Macrophages ◽

Structure Activity ◽

Relationship Study

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Design and Synthesis of Fluorinated and/or Hydroxylated 2‐Arylidene‐1‐indanone Derivatives as an Inhibitor of LPS‐stimulated ROS Production in RAW 264.7 Macrophages with Structure–Activity Relationship Study

Bulletin of the Korean Chemical Society ◽

10.1002/bkcs.11618 ◽

2018 ◽

Vol 39 (12) ◽

pp. 1432-1441 ◽

Cited By ~ 2

Author(s):

Pramila Katila ◽

Aastha Shrestha ◽

Aarajana Shrestha ◽

Ritina Shrestha ◽

Pil‐Hoon Park ◽

...

Keyword(s):

Structure Activity Relationship ◽

Activity Relationship ◽

Raw 264.7 ◽

Ros Production ◽

Raw 264.7 Macrophages ◽

Design And Synthesis ◽

Structure Activity ◽

Relationship Study

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Inhibition of LPS-stimulated ROS production by fluorinated and hydroxylated chalcones in RAW 264.7 macrophages with structure-activity relationship study

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2017.01.061 ◽

2017 ◽

Vol 27 (5) ◽

pp. 1205-1209 ◽

Cited By ~ 12

Author(s):

Ganesh Bist ◽

Nirmala Tilija Pun ◽

Til Bahadur Thapa Magar ◽

Aarajana Shrestha ◽

Hye Jin Oh ◽

...

Keyword(s):

Structure Activity Relationship ◽

Activity Relationship ◽

Raw 264.7 ◽

Ros Production ◽

Raw 264.7 Macrophages ◽

Structure Activity ◽

Relationship Study

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Thieny/Furanyl-hydroxyphenylpropenones as Inhibitors of LPS-induced ROS and NO Production in RAW 264.7 Macrophages, and Their Structure-Activity Relationship Study

Bulletin of the Korean Chemical Society ◽

10.5012/bkcs.2014.35.8.2481 ◽

2014 ◽

Vol 35 (8) ◽

pp. 2481-2486 ◽

Cited By ~ 7

Author(s):

Tara Man Kadayat ◽

Mi Jin Kim ◽

Tae-Gyu Nam ◽

Pil-Hoon Park ◽

Eung-Seok Lee

Keyword(s):

Structure Activity Relationship ◽

Activity Relationship ◽

No Production ◽

Raw 264.7 ◽

Raw 264.7 Macrophages ◽

Structure Activity ◽

Relationship Study

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Design, synthesis, biological evaluation and structure-activity relationship study of quinazolin-4(3H)-one derivatives as novel USP7 inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113291 ◽

2021 ◽

pp. 113291

Author(s):

Peng Li ◽

Ying Liu ◽

Hua Yang ◽

Hong-Min Liu

Keyword(s):

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Relationship Study

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Design, Synthesis and Quantitative Structure-Activity Relationship Study of N-(3-Oxo-3,4-dihydro-2H-benzo(1,4)oxazine-7-carbonyl)guanidine Derivatives as Potent Na/H Exchange Inhibitors.

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.45.1975 ◽

1997 ◽

Vol 45 (12) ◽

pp. 1975-1983 ◽

Cited By ~ 3

Author(s):

Takeshi YAMAMOTO ◽

Manabu HORI ◽

Ikuo WATANABE ◽

Hisayoshi TSUTSUI ◽

Kengo HARADA ◽

...

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Design Synthesis ◽

Guanidine Derivatives ◽

Structure Activity ◽

Relationship Study

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Design, Synthesis, Biological Screening and Structure Activity Relationship Study of 4, 6-Dimethyl-2-(Substituted) Mercapto-3-(Substituted) Pyridines as Anti Tubercular Agents

American Journal of Infectious Diseases ◽

10.3844/ajidsp.2011.61.66 ◽

2011 ◽

Vol 7 (3) ◽

pp. 61-66 ◽

Cited By ~ 1

Author(s):

Rozita

Keyword(s):

Structure Activity Relationship ◽

Activity Relationship ◽

Biological Screening ◽

Design Synthesis ◽

Structure Activity ◽

Substituted Pyridines ◽

Relationship Study

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Design, synthesis and structure-activity relationship study of novel urea compounds as FGFR1 inhibitors to treat metastatic triple-negative breast cancer

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2020.112866 ◽

2021 ◽

Vol 209 ◽

pp. 112866

Author(s):

Md Ashraf-Uz-Zaman ◽

Sadisna Shahi ◽

Racheal Akwii ◽

Md Sanaullah Sajib ◽

Mohammad Jodeiri Farshbaf ◽

...

Keyword(s):

Breast Cancer ◽

Triple Negative Breast Cancer ◽

Triple Negative ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Relationship Study ◽

Urea Compounds

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Design, synthesis, and structure–activity relationship study of bicyclic piperazine analogs of indole-3-carboxamides as novel cannabinoid CB1 receptor agonists

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2010.10.061 ◽

2010 ◽

Vol 20 (24) ◽

pp. 7327-7330 ◽

Cited By ~ 16

Author(s):

Elizabeth M. Moir ◽

Kazuya Yoshiizumi ◽

Jim Cairns ◽

Phillip Cowley ◽

Morag Ferguson ◽

...

Keyword(s):

Structure Activity Relationship ◽

Cb1 Receptor ◽

Activity Relationship ◽

Cannabinoid Cb1 Receptor ◽

Design Synthesis ◽

Receptor Agonists ◽

Structure Activity ◽

Relationship Study

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ChemInform Abstract: Design, Synthesis and Quantitative Structure-Activity Relationship Study of N-(3-Oxo-3,4-dihydro-2H-benzo[1,4]oxazine-7-carbonyl)guanidine Derivatives as Potent Na/H Exchange Inhibitors.

ChemInform ◽

10.1002/chin.199823160 ◽

2010 ◽

Vol 29 (23) ◽

pp. no-no

Author(s):

T. YAMAMOTO ◽

M. HORI ◽

I. WATANABE ◽

H. TSUTSUI ◽

K. HARADA ◽

...

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Design Synthesis ◽

Guanidine Derivatives ◽

Structure Activity ◽

Relationship Study

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