scholarly journals Prognostic impact of Ki‐67 proliferative index in resectable pancreatic ductal adenocarcinoma

BJS Open ◽  
2019 ◽  
Vol 3 (5) ◽  
pp. 646-655
Author(s):  
I. Pergolini ◽  
S. Crippa ◽  
M. Pagnanelli ◽  
G. Belfiori ◽  
A. Pucci ◽  
...  
Keyword(s):  
Pancreatic Ductal Adenocarcinoma ◽  
Ductal Adenocarcinoma ◽  
Prognostic Impact ◽  
Proliferative Index ◽  
Ki 67

Prognostic impact of Ki-67 proliferative index in resectable pancreatic ductal adenocarcinoma

Pancreatology ◽  
2018 ◽  
Vol 18 (4) ◽  
pp. S84
Author(s):  
Ilaria Pergolini ◽  
Stefano Crippa ◽  
Michele Pagnanelli ◽  
Giulio Belfiori ◽  
Alessandro Pucci ◽  
...  
Keyword(s):  
Pancreatic Ductal Adenocarcinoma ◽  
Ductal Adenocarcinoma ◽  
Prognostic Impact ◽  
Proliferative Index ◽  
Ki 67

scholarly journals Microvascular density and endothelial area correlate with Ki-67 proliferative index in surgically-treated pancreatic ductal adenocarcinoma patients

2015 ◽  
Vol 10 (2) ◽  
pp. 967-971 ◽  
Author(s):  
MICHELE AMMENDOLA ◽  
ROSARIO SACCO ◽  
ILARIA MARECH ◽  
GIUSEPPE SAMMARCO ◽  
VALERIA ZUCCALÀ ◽  
...  
Keyword(s):  
Pancreatic Ductal Adenocarcinoma ◽  
Microvascular Density ◽  
Ductal Adenocarcinoma ◽  
Proliferative Index ◽  
Ki 67

AB053. P024. Ki-67 proliferative index in resectable pancreatic ductal adenocarcinoma: does it have a prognostic role?

2018 ◽  
Vol 1 (1) ◽  
pp. AB053-AB053
Author(s):  
Francesca Aleotti ◽  
Ilaria Pergolini ◽  
Stefano Crippa ◽  
Michele Pagnanelli ◽  
Giulio Belfiori ◽  
...  
Keyword(s):  
Pancreatic Ductal Adenocarcinoma ◽  
Ductal Adenocarcinoma ◽  
Prognostic Role ◽  
Proliferative Index ◽  
Ki 67

Prognostic impact of VEGF, MMP-2 and TGF detection in pancreatic ductal adenocarcinoma

Pancreatology ◽  
2017 ◽  
Vol 17 (3) ◽  
pp. S103
Author(s):  
Pavel Skalicky ◽  
Jana Tesaříková ◽  
Dušan Klos ◽  
Jozef Škarda ◽  
Martin Loveček
Keyword(s):  
Pancreatic Ductal Adenocarcinoma ◽  
Ductal Adenocarcinoma ◽  
Prognostic Impact

Establishment of patient-derived tumor xenograft (PDX) model as artificially-created liver metastasis using cryopreserved pancreatic ductal adenocarcinoma.

2020 ◽  
Vol 38 (4_suppl) ◽  
pp. 729-729
Author(s):  
Kenjiro Kimura ◽  
Ryota Tanaka ◽  
Ryosuke Amano ◽  
Shoji Kubo ◽  
Hiroaki Tanaka ◽  
...  
Keyword(s):  
Liver Metastasis ◽  
Liver Transplant ◽  
Pancreatic Ductal Adenocarcinoma ◽  
Tumor Xenograft ◽  
Ductal Adenocarcinoma ◽  
Ki 67 ◽  
Nsg Mice ◽  
Patient Derived Xenograft ◽  
Pdx Model ◽  
Successful Establishment

729 Background: Translational research using patient-derived tumor xenograft (PDX) model is progressing rapidly, and is also becoming widespread in pancreatic cancer research. The purpose of this study was to establish the liver transplant PDX model as artificially-created liver metastasis with cryopreserved primary pancreatic ductal adenocarcinoma(PDAC). Methods: The primary PDAC from 10 patients were cryopreserved and transplanted into NSG mice using liver pocket method. For engraftment and similarity evaluation, H&E staining and immunohistochemical staining such as Ki-67, p53, SMAD4, and MUC1 were performed. Results: Patient-derived xenograft was succeeded in 6 cases (60%), 10 mice (33.3%). Ki-67 index of primary PDAC and the interval of cryopreservation were significantly related to successful engraftment, respectively (p = 0.003, p = 0.007). Conclusions: In this study, we succeeded in establishing a liver transplant PDX mouse model as a preclinical platform. The factors such as Ki-67 index and the interval of cryopreservation would affect the successful establishment.

Prognostic impact of MMP-2 and TGF detection in pancreatic ductal adenocarcinoma

Pancreatology ◽  
2015 ◽  
Vol 15 (3) ◽  
pp. S44
Author(s):  
Pavel Skalicky ◽  
Jana Tesarikova ◽  
Martin Lovecek ◽  
Jozef Skarda ◽  
Cestmir Neoral
Keyword(s):  
Pancreatic Ductal Adenocarcinoma ◽  
Ductal Adenocarcinoma ◽  
Prognostic Impact

Mo1658 Prognostic Impact of Para-Aortic Lymph Node Micrometastasis in Pancreatic Ductal Adenocarcinoma

2015 ◽  
Vol 148 (4) ◽  
pp. S-1164
Author(s):  
Toshiaki Komo ◽  
Yoshiaki Murakami ◽  
Kenichiro Uemura ◽  
Yasushi Hashimoto ◽  
Naru Kondo ◽  
...  
Keyword(s):  
Lymph Node ◽  
Pancreatic Ductal Adenocarcinoma ◽  
Ductal Adenocarcinoma ◽  
Prognostic Impact ◽  
Lymph Node Micrometastasis ◽  
Aortic Lymph Node
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