Splenic autotransplantation after splenectomy: Tuftsin activity correlates with residual splenic function

1994 ◽  
Vol 81 (5) ◽  
pp. 716-718 ◽  
Author(s):  
G. Zoli ◽  
G. R. Corazza ◽  
G. D'Amato ◽  
R. Bartoli ◽  
F. Baldoni ◽  
...  
Keyword(s):  
Splenic Autotransplantation ◽  
Splenic Function

Heterotopic splenic autotransplantation in a neonate with splenic rupture, leading to normal splenic function

1996 ◽  
Vol 31 (2) ◽  
pp. 239-240 ◽  
Author(s):  
Atsuyuki Yamataka ◽  
Toshio Fujiwara ◽  
Takashi Tsuchioka ◽  
Yusaku Kurosu ◽  
Masakatsu Sunagawa
Keyword(s):  
Splenic Rupture ◽  
Splenic Autotransplantation ◽  
Splenic Function

scholarly journals Alterations in splenic function and gene expression in mice with depressive-like behavior induced by exposure to corticosterone

2017 ◽  
Vol 39 (2) ◽  
pp. 327-336 ◽  
Author(s):  
Heqin Zhan ◽  
Feng Huang ◽  
Fulin Yan ◽  
Zhenghang Zhao ◽  
Jixia Zhang ◽  
...  
Keyword(s):  
Gene Expression ◽  
Splenic Function

Splenic function in Saudi children with sickle cell disease

1984 ◽  
Vol 4 (2) ◽  
pp. 87-91 ◽  
Author(s):  
Ahmad Mallouh ◽  
G. M. Burke ◽  
M. Salamah ◽  
M. S. Ahmad
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Cell Disease ◽  
Splenic Function

Exogenous and Endogenous Angiogenic Stimuli do not Augment Splenic Autotransplantation

2002 ◽  
Vol 168 (4) ◽  
pp. 247-250 ◽  
Author(s):  
Richard E. Power ◽  
Elaine W. Kay ◽  
David Bouchier-Hayes
Keyword(s):  
Splenic Autotransplantation

Bacterial Infection and Splenic Reticuloendothelial Function in Children with Hemoglobin SC Disease

PEDIATRICS ◽  
1983 ◽  
Vol 72 (1) ◽  
pp. 93-98
Author(s):  
George R. Buchanan ◽  
Susan J. Smith ◽  
Christine A. Holtkamp ◽  
John P. Fuseler
Keyword(s):  
Bacterial Infection ◽  
Bacterial Infections ◽  
Infection Risk ◽  
Bacterial Disease ◽  
Normal Children ◽  
Splenic Function ◽  
Focus Of Infection ◽  
Serious Bacterial Infections ◽  
Primary Focus ◽  
Hemoglobin Sc Disease

Although the epidemiology and pathophysiology of serious bacterial infection in homozygous sickle cell anemia (SS disease) have become increasingly well understood, information about infection risk and splenic reticuloendothelial function in hemoglobin SC disease is quite limited. Therefore, the type and frequency of invasive bacterial disease were examined in 51 children with SC disease followed for 370 person-years and splenic function was assessed in 31 patients by quantitation of pitted erythrocytes. Seven serious bacterial infections occurred in four of the patients, five due to Streptococcus pneumoniae and two to Haemophilus influenzae. A primary focus of infection was present in all episodes, none of which proved fatal. Although 30 episodes of pneumonia or chest syndrome occurred in 20 of the patients, a bacterial etiology was proven in only three instances. Splenic function was usually impaired, with a mean pit count of 7.1% ± 8.2% (range 0% to 22.9%). This is significantly greater than normal, but less than pit counts in patients with SS disease or asplenic subjects. Children with SC disease may have a greater risk of bacterial infection than normal children, but their infection rate is not nearly as high as that in patients with SS disease.

Oral Penicillin Prophylaxis in Children with Impaired Splenic Function: A Study of Compliance

PEDIATRICS ◽  
1982 ◽  
Vol 70 (6) ◽  
pp. 926-930
Author(s):  
George R. Buchanan ◽  
Jane D. Siegel ◽  
Susan J. Smith ◽  
Bonnie M. DePasse
Keyword(s):  
Poor Compliance ◽  
Disc Diffusion ◽  
Cell Disease ◽  
Splenic Function ◽  
Oral Penicillin ◽  
Diffusion Technique ◽  
Life Threatening ◽  
Penicillin Prophylaxis ◽  
Urine Specimens ◽  
Infants And Young Children

One measure used to prevent overwhelming sepsis due to Streptococcus pneumoniae in children with defective splenic function is oral penicillin prophylaxis. However, a frequently cited argument against this approach is the likelihood of poor compliance. Compliance was studied by examining urine specimens for penicillin by the Sarcina lutea disc diffusion technique in 22 surgically asplenic children, two patients following bone marrow transplantation, and 38 infants and young children with sickle cell disease. Multiple specimens (mean 3.5 per patient) were examined in 43 of the children. Overall, 125/188 (66%) of the urine samples contained penicillin, indicating compliance within the previous 12 to 24 hours. Compliance tended to improve on subsequent clinic visits. These relatively good results were attributed to an intensive educational program in which repetitive efforts are made to counsel patients and parents about the risks of life-threatening infection. Poor compliance should no longer be invoked as a reason not to study the efficacy of prophylactic penicillin in functionally or surgically asplenic subjects.

scholarly journals Splenic function in alcoholic liver disease.

Gut ◽  
1992 ◽  
Vol 33 (10) ◽  
pp. 1386-1389 ◽  
Author(s):  
A F Muller ◽  
P J Toghill
Keyword(s):  
Liver Disease ◽  
Alcoholic Liver Disease ◽  
Splenic Function
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