Results of the Duhamel operation in the treatment of idiopathic megarectum and megacolon

1991 ◽  
Vol 78 (6) ◽  
pp. 661-663 ◽  
Author(s):  
G. Stabile ◽  
M. A. Kamm ◽  
P. R. Hawley ◽  
J. E. Lennard-Jones
Keyword(s):  
Idiopathic Megarectum

Vertical reduction rectoplasty: a new treatment for idiopathic megarectum

2000 ◽  
Vol 87 (9) ◽  
pp. 1203-1208 ◽  
Author(s):  
N. S. Williams ◽  
O. A. Fajobi ◽  
P. J. Lunniss ◽  
S. M. Scott ◽  
A. J. P. Eccersley ◽  
...  
Keyword(s):  
New Treatment ◽  
Idiopathic Megarectum

Idiopathic megacolon and megarectum in an adult treated with laparoscopic modified Duhamel procedure

2021 ◽  
Vol 14 (6) ◽  
pp. e240209
Author(s):  
Maureen Elvira Padernal Villanueva ◽  
Marc Paul Jose Lopez ◽  
Mark Augustine S Onglao
Keyword(s):  
Emergency Department ◽  
Chronic Constipation ◽  
Ganglion Cells ◽  
Rectal Biopsy ◽  
Full Thickness ◽  
Postoperative Course ◽  
Idiopathic Megacolon ◽  
Duhamel Procedure ◽  
Idiopathic Megarectum ◽  
Sigmoid Loop Colostomy

Idiopathic megacolon (IMC) and idiopathic megarectum (IMR) describe an abnormality of the colon or rectum, characterised by a permanent dilatation of the bowel diameter in the absence of an identifiable cause. We present a 23-year-old woman with chronic constipation and excessive straining during defecation who presented at the emergency department in partial gut obstruction with a palpable fecaloma. Manual faecal disimpaction and a sigmoid loop colostomy was initially done. A full thickness rectal biopsy was positive for ganglion cells. Further workup led to the diagnosis of chronic IMC and IMR. The patient underwent laparoscopic modified Duhamel procedure, with an uneventful postoperative course.

Surgical treatment of idiopathic megarectum in constipated children

2019 ◽  
Vol 54 (7) ◽  
pp. 1379-1383 ◽  
Author(s):  
Igor V. Kirgizov ◽  
Sergey V. Minaev ◽  
Ilya Shishkin ◽  
Svetlana Aprosimova ◽  
Luiza Ukhina
Keyword(s):  
Surgical Treatment ◽  
Idiopathic Megarectum

scholarly journals Systematic Review of Surgical Options for Idiopathic Megarectum and Megacolon

2005 ◽  
Vol 241 (4) ◽  
pp. 562-574 ◽  
Author(s):  
Marc A. Gladman ◽  
S Mark Scott ◽  
Peter J. Lunniss ◽  
Norman S. Williams
Keyword(s):  
Systematic Review ◽  
Surgical Options ◽  
Idiopathic Megarectum

Enteric innervation in idiopathic megarectum and megacolon

1996 ◽  
Vol 11 (6) ◽  
pp. 264-271 ◽  
Author(s):  
J. M. Gattuso ◽  
C. H. V. Hoyle ◽  
P. Milner ◽  
M. A. Kamm ◽  
G. Burnstock
Keyword(s):  
Idiopathic Megarectum ◽  
Enteric Innervation

Partial colectomy and coloanal anastomosis for idiopathic megarectum and megacolon

1992 ◽  
Vol 35 (2) ◽  
pp. 158-162 ◽  
Author(s):  
Giorgio Stabile ◽  
Michael A. Kamm ◽  
Robin K. S. Phillips ◽  
Peter R. Hawley ◽  
John E. Lennard-Jones
Keyword(s):  
Coloanal Anastomosis ◽  
Partial Colectomy ◽  
Idiopathic Megarectum

Medium-term results of vertical reduction rectoplasty and sigmoid colectomy for idiopathic megarectum

2005 ◽  
Vol 92 (5) ◽  
pp. 624-630 ◽  
Author(s):  
M. A. Gladman ◽  
N. S. Williams ◽  
S. M. Scott ◽  
O. A. Ogunbiyi ◽  
P. J. Lunniss
Keyword(s):  
Sigmoid Colectomy ◽  
Medium Term ◽  
Idiopathic Megarectum

scholarly journals Pathology of idiopathic megarectum and megacolon

Gut ◽  
1997 ◽  
Vol 41 (2) ◽  
pp. 252-257 ◽  
Author(s):  
J M Gattuso ◽  
M A Kamm ◽  
I C Talbot
Keyword(s):  
Smooth Muscle ◽  
Longitudinal Muscle ◽  
Periodic Acid ◽  
Circular Muscle ◽  
Muscularis Mucosae ◽  
Periodic Acid Schiff ◽  
Muscle Fibrosis ◽  
Idiopathic Megacolon ◽  
Resected Tissue ◽  
Idiopathic Megarectum

Background—The aetiology and pathology of both idiopathic megarectum and idiopathic megacolon are unknown. In particular, it is unknown whether there are abnormalities involving enteric nerves or smooth muscle.Methods—Resected tissue was examined from 24 patients who underwent surgery for idiopathic megarectum, from six patients who had tissue resected for idiopathic megacolon, and 17 control patients who had surgery for non-obstructing large bowel cancer. Qualitative and quantitative histological examination was performed after staining with haematoxylin and eosin, periodic acid Schiff (PAS), Martius scarlet blue (MSB), and phosphotungstic acid haematoxylin (PTAH). Neural and glial tissue were examined after immunostaining with S100 and PGP9.5.Results—Compared with controls, patients with idiopathic megarectum had significant thickening of their muscularis mucosae (median 78 v 33 μm, p<0.005), circular muscle (1000 v 633 μm, p<0.005), and longitudinal muscle (1083v 303 μm, p<0.005), despite rectal dilatation. This thickening was relatively greater in the longitudinal than in the circular muscle. Fibrosis of the longitudinal muscle was seen, using MSB staining, in 58%, of circular muscle in 38%, and of muscularis mucosae in 29% of patients. The relation between muscle thickening and fibrosis was variable. The density of neural tissue in the longitudinal muscle seemed to be reduced in patients with idiopathic megarectum. There was no thickening of enteric muscle or alteration in the density of innervation in patients with idiopathic megacolon.Conclusion—There is notable thickening of the enteric smooth muscle in patients with idiopathic megarectum, but the architecture of the enteric innervation seems to be intact. Functional abnormalities of the latter remain a possible cause of the smooth muscle hypertrophy.

Results of stoma formation for idiopathic megarectum and megacolon

1992 ◽  
Vol 7 (2) ◽  
pp. 82-84 ◽  
Author(s):  
G. Stabile ◽  
M. A. Kamm ◽  
P. R. Hawley ◽  
J. E. Lennard-Jones
Keyword(s):  
Stoma Formation ◽  
Idiopathic Megarectum
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