The release of vasoactive intestinal peptide during altered mid-gut blood flow

1980 ◽  
Vol 67 (2) ◽  
pp. 131-134 ◽  
Author(s):  
P. G. Bateson ◽  
K. D. Buchanan ◽  
Davina M. Stewart ◽  
T. G. Parks
Keyword(s):  
Blood Flow ◽  
Vasoactive Intestinal Peptide

Effect of synthetic chicken vasoactive intestinal peptide on pancreatic blood flow and on exocrine and endocrine secretions of the pancreas in dogs

1983 ◽  
Vol 28 (8) ◽  
pp. 724-732 ◽  
Author(s):  
Kazutomo Inoue ◽  
Tamotsu Kawano ◽  
Koichi Shima ◽  
Teruji Kim ◽  
Takashi Suzuki ◽  
...  
Keyword(s):  
Blood Flow ◽  
Vasoactive Intestinal Peptide ◽  
Pancreatic Blood Flow

Vasoactive Intestinal Peptide Treatment that Increases Thyroid Blood Flow Fails to Alter Plasma T3 or T4 Levels in the Rat

1988 ◽  
Vol 47 (6) ◽  
pp. 567-574 ◽  
Author(s):  
Linda J. Huffman ◽  
John M. Connors ◽  
Beatrix H. White ◽  
George A. Hedge
Keyword(s):  
Blood Flow ◽  
Vasoactive Intestinal Peptide ◽  
Peptide Treatment

Postprandial Portal Venous Blood Flow and Portal Plasma Vasoactive Intestinal Peptide in Man

1988 ◽  
Vol 527 (1 Vasoactive In) ◽  
pp. 591-594 ◽  
Author(s):  
CARL HOLM ◽  
BJÖRN BIBER ◽  
BENGT GUSTAVSSON ◽  
IAN MILSOM ◽  
OLA WINSÖ ◽  
...  
Keyword(s):  
Blood Flow ◽  
Vasoactive Intestinal Peptide ◽  
Venous Blood ◽  
Venous Blood Flow ◽  
Portal Venous Blood Flow ◽  
Portal Plasma ◽  
Portal Venous Blood

Effects of peptide YY on the human cardiovascular system: reversal of responses to vasoactive intestinal peptide

1992 ◽  
Vol 263 (4) ◽  
pp. E740-E747 ◽  
Author(s):  
R. J. Playford ◽  
M. A. Benito-Orfila ◽  
P. Nihoyannopoulos ◽  
K. A. Nandha ◽  
J. Cockcroft ◽  
...  
Keyword(s):  
Heart Rate ◽  
Blood Flow ◽  
Cardiac Output ◽  
Cardiovascular System ◽  
Vasoactive Intestinal Peptide ◽  
Brachial Artery ◽  
Peptide Yy ◽  
Intestinal Secretion ◽  
Venous Occlusion ◽  
Human Cardiovascular System

Peptide YY (PYY) reverses the increased intestinal secretion stimulated by vasoactive intestinal peptide (VIP) in humans. VIP also dilates blood vessels, so we investigated the effect of PYY on the cardiovascular system. Six volunteers received PYY, 0.4 and 1.2 pmol.kg-1 x min-1 i.v. for 2 h, reproducing plasma levels seen postprandially and during a diarrheal illness, respectively. Cardiac function was assessed by echocardiography. PYY infused at 0.4 pmol.kg-1 x min-1 had no effect on cardiovascular parameters. PYY infused at 1.2 pmol.kg-1 x min-1 caused a fall in both stroke volume from 128 +/- 8 to 110 +/- 8 ml/beat (mean +/- 95 confidence interval, P < 0.01) and cardiac output from 7.2 +/- 0.4 to 6.1 +/- 0.4 l/min (P < 0.01). Effects of infusion of PYY into the brachial artery at doses of 0-16 pmol/min were assessed using venous occlusion plethysmography in six subjects. PYY infusion caused a dose-dependent fall in forearm blood flow. Six subjects received VIP, 5 pmol.kg-1 x min-1 i.v., causing a rise in heart rate from 55 +/- 3 to 70 +/- 3 beats/min and increased cardiac output from 7.3 +/- 1.1 to 13.1 +/- 1.1 l/min. The addition of PYY, 0.4 pmol.kg-1 x min-1 i.v., did not affect the heart rate significantly but decreased the cardiac output to 10.4 +/- 1.1 l/min (P < 0.01). Infusions of PYY into the brachial artery at 5 pmol/min decreased local vasodilation induced by VIP infused at 2 pmol/min at the same site by 40% (P < 0.01), even though this dose of PYY had no significant effect on local blood flow when given alone.(ABSTRACT TRUNCATED AT 250 WORDS)

Effect of peptide YY on the blood flow response to vasoactive intestinal peptide in the human forearm vascular bed

1992 ◽  
Vol 40 (2) ◽  
pp. 228
Author(s):  
RJ Playford ◽  
J Cockcroft ◽  
KA Nandha ◽  
JM Ritter ◽  
MA Benito-Orfila ◽  
...  
Keyword(s):  
Blood Flow ◽  
Vasoactive Intestinal Peptide ◽  
Peptide Yy ◽  
Blood Flow Response ◽  
Flow Response ◽  
Vascular Bed ◽  
Human Forearm
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