scholarly journals Functional outcomes from a randomized trial of early closure of temporary ileostomy after rectal excision for cancer

2019 ◽  
Vol 106 (5) ◽  
pp. 645-652 ◽  
Author(s):  
C. Keane ◽  
J. Park ◽  
S. Öberg ◽  
A. Wedin ◽  
D. Bock ◽  
...  
Keyword(s):  
Randomized Trial ◽  
Functional Outcomes ◽  
Rectal Excision ◽  
Temporary Ileostomy ◽  
Early Closure

scholarly journals Cost analysis in a randomized trial of early closure of a temporary ileostomy after rectal resection for cancer (EASY trial)

2019 ◽  
Vol 34 (1) ◽  
pp. 69-76
Author(s):  
Jennifer Park ◽  
Eva Angenete ◽  
David Bock ◽  
Adiela Correa-Marinez ◽  
Anne K. Danielsen ◽  
...  
Keyword(s):  
Cost Analysis ◽  
Randomized Trial ◽  
Rectal Resection ◽  
Temporary Ileostomy ◽  
Early Closure

scholarly journals Quality of life in a randomized trial of early closure of temporary ileostomy after rectal resection for cancer (EASY trial)

2017 ◽  
Vol 105 (3) ◽  
pp. 244-251 ◽  
Author(s):  
J. Park ◽  
A. K. Danielsen ◽  
E. Angenete ◽  
D. Bock ◽  
A. C. Marinez ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Randomized Trial ◽  
Rectal Resection ◽  
Temporary Ileostomy ◽  
Early Closure

scholarly journals Current surgical results with low-grade brain arteriovenous malformations

2015 ◽  
Vol 122 (4) ◽  
pp. 912-920 ◽  
Author(s):  
Matthew B. Potts ◽  
Darryl Lau ◽  
Adib A. Abla ◽  
Helen Kim ◽  
William L. Young ◽  
...  
Keyword(s):  
Randomized Trial ◽  
Functional Outcomes ◽  
Arteriovenous Malformations ◽  
Preoperative Embolization ◽  
Low Grade ◽  
Cure Rate ◽  
Brain Arteriovenous Malformations ◽  
First Line Therapy ◽  
Delayed Hemorrhage ◽  
Martin Grade

OBJECT Resection is an appealing therapy for brain arteriovenous malformations (AVMs) because of its high cure rate, low complication rate, and immediacy, and has become the first-line therapy for many AVMs. To clarify safety, efficacy, and outcomes associated with AVM resection in the aftermath of A Randomized Trial of Unruptured Brain AVMs (ARUBA), the authors reviewed their experience with low-grade AVMs—the most favorable AVMs for surgery and the ones most likely to have been selected for treatment outside of ARUBA's randomization process. METHODS A prospective AVM registry was searched to identify patients with Spetzler-Martin Grade I and II AVMs treated using resection during a 16-year period. RESULTS Of the 232 surgical patients included, 120 (52%) presented with hemorrhage, 33% had Spetzler-Martin Grade I, and 67% had Grade II AVMs. Overall, 99 patients (43%) underwent preoperative embolization, with unruptured AVMs embolized more often than ruptured AVMs. AVM resection was accomplished in all patients and confirmed angiographically in 218 patients (94%). There were no deaths among patients with unruptured AVMs. Good outcomes (modified Rankin Scale [mRS] score 0–1) were found in 78% of patients, with 97% improved or unchanged from their preoperative mRS scores. Patients with unruptured AVMs had better functional outcomes (91% good outcome vs 65% in the ruptured group, p = 0.0008), while relative outcomes were equivalent (98% improved/unchanged in patients with ruptured AVMs vs 96% in patients with unruptured AVMs). CONCLUSIONS Surgery should be regarded as the “gold standard” therapy for the majority of low-grade AVMs, utilizing conservative embolization as a preoperative adjunct. High surgical cure rates and excellent functional outcomes in patients with both ruptured and unruptured AVMs support a dominant surgical posture for low-grade AVMS, with radiosurgery reserved for risky AVMs in deep, inaccessible, and highly eloquent locations. Despite the technological advances in endovascular and radiosurgical therapy, surgery still offers the best cure rate, lowest risk profile, and greatest protection against hemorrhage for low-grade AVMs. ARUBA results are influenced by a low randomization rate, bias toward nonsurgical therapies, a shortage of surgical expertise, a lower rate of complete AVM obliteration, a higher rate of delayed hemorrhage, and short study duration. Another randomized trial is needed to reestablish the role of surgery in unruptured AVM management.

scholarly journals Early Closure of a Temporary Ileostomy in Patients With Rectal Cancer

2017 ◽  
Vol 265 (2) ◽  
pp. 284-290 ◽  
Author(s):  
Anne K. Danielsen ◽  
Jennifer Park ◽  
Jens E. Jansen ◽  
David Bock ◽  
Stefan Skullman ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Temporary Ileostomy ◽  
Early Closure

The effect of prehabilitation on the range of motion and functional outcomes in patients following the total knee or hip arthroplasty: A pilot randomized trial

2016 ◽  
Vol 32 (4) ◽  
pp. 262-270 ◽  
Author(s):  
Stuart Cavill ◽  
Kylie McKenzie ◽  
Adrienne Munro ◽  
Janice McKeever ◽  
Lucy Whelan ◽  
...  
Keyword(s):  
Randomized Trial ◽  
Range Of Motion ◽  
Hip Arthroplasty ◽  
Functional Outcomes ◽  
Total Knee

scholarly journals Early closure of temporary ileostomy--the EASY trial: protocol for a randomised controlled trial

BMJ Open ◽  
2011 ◽  
Vol 1 (1) ◽  
pp. e000162-e000162 ◽  
Author(s):  
A. K. Danielsen ◽  
A. Correa-Marinez ◽  
E. Angenete ◽  
S. Skullmann ◽  
E. Haglind ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Controlled Trial ◽  
Trial Protocol ◽  
Temporary Ileostomy ◽  
Early Closure ◽  
Randomised Controlled

Bioresorbable Adhesion Barrier Facilitates Early Closure of the Defunctioning Ileostomy After Rectal Excision

2003 ◽  
Vol 46 (9) ◽  
pp. 1200-1207 ◽  
Author(s):  
Choong-Leong Tang ◽  
Francis Seow-Choen ◽  
Stephanie Fook-Chong ◽  
Kong-Weng Eu
Keyword(s):  
Rectal Excision ◽  
Adhesion Barrier ◽  
Defunctioning Ileostomy ◽  
Early Closure
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