SDF‐1α gene‐activated collagen scaffold drives functional differentiation of human Schwann cells for wound healing applications

Author(s):  
Ashang L. Laiva ◽  
Fergal J. O'Brien ◽  
Michael B. Keogh
2013 ◽  
Vol 182 (2) ◽  
pp. 353-361 ◽  
Author(s):  
Pham Hieu Liem ◽  
Naoki Morimoto ◽  
Ran Ito ◽  
Katsuya Kawai ◽  
Shigehiko Suzuki

2018 ◽  
Vol 26 (5) ◽  
pp. 392-397 ◽  
Author(s):  
Walison N. Silva ◽  
Caroline Leonel ◽  
Pedro H. D. M. Prazeres ◽  
Isadora F. G. Sena ◽  
Daniel A. P. Guerra ◽  
...  

2012 ◽  
Vol 101B (4) ◽  
pp. 560-567 ◽  
Author(s):  
Venkatachalam Natarajan ◽  
Natarajan Krithica ◽  
Balaraman Madhan ◽  
Praveen Kumar Sehgal

2020 ◽  
Vol 8 (22) ◽  
pp. 6337-6349
Author(s):  
Ge Long ◽  
Dingyang Liu ◽  
Xi He ◽  
Yeyu Shen ◽  
Yannan Zhao ◽  
...  

Chronic diabetic wounds, which are associated with persistent inflammation and impaired angiogenesis, occur frequently in diabetic patients.


2015 ◽  
Vol 19 (2) ◽  
pp. 167-174 ◽  
Author(s):  
Hiromu Masuoka ◽  
Naoki Morimoto ◽  
Michiharu Sakamoto ◽  
Shuichi Ogino ◽  
Shigehiko Suzuki

2005 ◽  
Vol 277-279 ◽  
pp. 12-18 ◽  
Author(s):  
Eun Kyung Yang ◽  
Jung Keug Park ◽  
Jae Il Ahn ◽  
Hee Gu Lee ◽  
Seong Jun Seo ◽  
...  

Human skin substitutes are needed for implantation and wound repair based on the new concept of tissue engineering in combination with biomaterials and cell biological technology. However, failure sometimes occurs when the wound healing is delayed in vivo due to acute inflammation resulting from the early degradation of the transplanted biomaterials. Accordingly, the current study modified conventional biomaterials to overcome early degradation and strong inflammation. In a conventional skin substitute, the animal origin collagenous materials have a slight antigenicity as xenogenic materials, however, the modified method was able to obtain a low antigenicity and anti-inflammation effect using atelo-collagen and an amniotic component. The tyrosine content in the developed atelo-collagen, representing the antigenicity, was reduced from 0.590% to 0.046% based on an HPLC analysis. In addition, to reduce the inflammation and foreign material reaction, an amniotic component was applied to the atelo-collagen materials. While, to enhance the wound healing, the modified skin substitute was developed as a composite matrix of an atelo-collagen scaffold with an amniotic membrane component. A quantitative analysis of hEGF in the amniotic membrane was also performed using different processing methods. Finally, a tissueengineered skin substitute was constructed by cultivating skin cells in the collagen scaffold attached to an amniotic membrane.


2015 ◽  
Vol 3 (7) ◽  
pp. 1415-1425 ◽  
Author(s):  
N. Duraipandy ◽  
Rachita Lakra ◽  
Kunnavakkam Vinjimur Srivatsan ◽  
Usha Ramamoorthy ◽  
Purna Sai Korrapati ◽  
...  

Wound dressing material based on nano-biotechnological intervention by caging plumbagin on silver nanoparticle (PCSN) as a multi-site cross-linking agent of collagen scaffolds with potent anti-microbial and wound healing activity.


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