An adjustable multi-scale single beam acoustic tweezers based on ultrahigh frequency ultrasonic transducer

2017 ◽  
Vol 114 (11) ◽  
pp. 2637-2647 ◽  
Author(s):  
Xiaoyang Chen ◽  
Kwok Ho Lam ◽  
Ruimin Chen ◽  
Zeyu Chen ◽  
Ping Yu ◽  
...  
Keyword(s):  
Ultrasonic Transducer ◽  
Ultrahigh Frequency ◽  
Single Beam ◽  
Multi Scale ◽  
Acoustic Tweezers

scholarly journals Contactless microparticle control via ultrahigh frequency needle type single beam acoustic tweezers

2016 ◽  
Vol 109 (17) ◽  
pp. 173509 ◽  
Author(s):  
Chunlong Fei ◽  
Ying Li ◽  
Benpeng Zhu ◽  
Chi Tat Chiu ◽  
Zeyu Chen ◽  
...  
Keyword(s):  
Ultrahigh Frequency ◽  
Single Beam ◽  
Needle Type ◽  
Acoustic Tweezers

Single-Beam Acoustic Tweezers: A New Tool for Microparticle Manipulation

2013 ◽  
Vol 9 (4) ◽  
pp. 10 ◽  
Author(s):  
Ying Li ◽  
Jae Youn Hwang ◽  
K. Kirk Shung ◽  
Jungwoo Lee
Keyword(s):  
Single Beam ◽  
Acoustic Tweezers

scholarly journals Micro-particle manipulation by single beam acoustic tweezers based on hydrothermal PZT thick film

AIP Advances ◽  
2016 ◽  
Vol 6 (3) ◽  
pp. 035102 ◽  
Author(s):  
Benpeng Zhu ◽  
Jiong Xu ◽  
Ying Li ◽  
Tian Wang ◽  
Ke Xiong ◽  
...  
Keyword(s):  
Thick Film ◽  
Particle Manipulation ◽  
Single Beam ◽  
Acoustic Tweezers ◽  
Pzt Thick Film

Ultrahigh frequency ZnO silicon lens ultrasonic transducer for cell-size microparticle manipulation

2017 ◽  
Vol 729 ◽  
pp. 556-562 ◽  
Author(s):  
Chunlong Fei ◽  
Hsiu-Sheng Hsu ◽  
Arash Vafanejad ◽  
Ying Li ◽  
Pengfei Lin ◽  
...  
Keyword(s):  
Cell Size ◽  
Ultrasonic Transducer ◽  
Ultrahigh Frequency ◽  
Silicon Lens

scholarly journals Measurements of acoustic radiation force of ultrahigh frequency ultrasonic transducers using model-based approach

2021 ◽  
Author(s):  
Sangnam Kim ◽  
Sunho Moon ◽  
Sunghoon Rho ◽  
Sangpil Yoon
Keyword(s):  
Single Cell ◽  
Acoustic Radiation ◽  
Ultrasonic Transducer ◽  
Radiation Force ◽  
Solid Sphere ◽  
Acoustic Radiation Force ◽  
Ultrasonic Transducers ◽  
Ultrahigh Frequency ◽  
Cell Phenotype ◽  
Target Cells

AbstractEven though ultrahigh frequency ultrasonic transducers over 60 MHz have been used for single cell level manipulation such as intracellular delivery, acoustic tweezers, and stimulation to investigate cell phenotype and cell mechanics, no techniques have been available to measure actual acoustic radiation force (ARF) applied to target cells. Therefore, we have developed an approach to measure ARF of ultrahigh frequency ultrasonic transducers using theoretical model of the dynamics of a solid sphere in a gelatin phantom. To estimate ARF at the focus of 130 MHz transducer, we matched measured maximum displacements of a solid sphere with theoretical calculations. We selected appropriate ranges of input voltages and pulse durations for single cell applications and estimated ARF were in the range of tens of pN to nN. FRET live cell imaging was demonstrated to visualize calcium transport between cells after a target single cell was stimulated by the developed ultrasonic transducer.

scholarly journals Three dimensional acoustic tweezers with vortex streaming

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Junfei Li ◽  
Alexandru Crivoi ◽  
Xiuyuan Peng ◽  
Lu Shen ◽  
Yunjiao Pu ◽  
...  
Keyword(s):  
Acoustic Streaming ◽  
Three Dimensional ◽  
Radiation Force ◽  
Two Dimensions ◽  
Single Beam ◽  
Scale Particle ◽  
Acoustic Tweezers ◽  
Third Dimension ◽  
Contact Free ◽  
Micrometer Scale

AbstractAcoustic tweezers use ultrasound for contact-free manipulation of particles from millimeter to sub-micrometer scale. Particle trapping is usually associated with either radiation forces or acoustic streaming fields. Acoustic tweezers based on single-beam focused acoustic vortices have attracted considerable attention due to their selective trapping capability, but have proven difficult to use for three-dimensional (3D) trapping without a complex transducer array and significant constraints on the trapped particle properties. Here we demonstrate a 3D acoustic tweezer in fluids that uses a single transducer and combines the radiation force for trapping in two dimensions with the streaming force to provide levitation in the third dimension. The idea is demonstrated in both simulation and experiments operating at 500 kHz, and the achieved levitation force reaches three orders of magnitude larger than for previous 3D trapping. This hybrid acoustic tweezer that integrates acoustic streaming adds an additional twist to the approach and expands the range of particles that can be manipulated.

scholarly journals A feasibility study of in vivo applications of single beam acoustic tweezers

2014 ◽  
Vol 105 (17) ◽  
pp. 173701 ◽  
Author(s):  
Ying Li ◽  
Changyang Lee ◽  
Ruimin Chen ◽  
Qifa Zhou ◽  
K. Kirk Shung
Keyword(s):  
Feasibility Study ◽  
Single Beam ◽  
Acoustic Tweezers

Calibration of Trapping Force on Cell-Size Objects From Ultrahigh-Frequency Single-Beam Acoustic Tweezer

2016 ◽  
Vol 63 (11) ◽  
pp. 1988-1995 ◽  
Author(s):  
Hae Gyun Lim ◽  
Ying Li ◽  
Ming-Yi Lin ◽  
Changhan Yoon ◽  
Changyang Lee ◽  
...  
Keyword(s):  
Cell Size ◽  
Ultrahigh Frequency ◽  
Single Beam ◽  
Trapping Force

scholarly journals Three dimensional acoustic tweezers with acoustic vortex streaming

2021 ◽  
Author(s):  
Junfei Li ◽  
Alexandru Crivoi ◽  
Xiuyuan Peng ◽  
Lu Shen ◽  
Yunjiao Pu ◽  
...  
Keyword(s):  
Acoustic Streaming ◽  
Three Dimensional ◽  
Radiation Force ◽  
Two Dimensions ◽  
Single Beam ◽  
Scale Particle ◽  
Acoustic Tweezers ◽  
Third Dimension ◽  
Contact Free ◽  
Micrometer Scale

Abstract Acoustic tweezers use ultrasound for contact-free manipulation of particles from millimeter to sub-micrometer scale. Particle trapping originated in either radiation forces or acoustic streaming fields. Acoustic tweezers based on single-beam focused acoustic vortices have attracted considerable attention due to their selective trapping capability, but have proven difficult to use for 3D trapping without a complex transducer array and significant constraints on the trapped particle properties. Here we demonstrate the first 3D acoustic tweezer that uses a single transducer and combines the radiation force for trapping in two dimensions with the streaming force to provide levitation in the third dimension. The idea is demonstrated in both simulation and experiments, and the achieved levitation force reaches three orders of magnitude larger than for previous 3D trapping. This hybrid acoustic tweezer that integrates acoustic streaming adds a new twist to the approach and expands the range of particles that can be manipulated.

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