Metabolic engineering of 3-hydroxypropionic acid biosynthesis inEscherichia coli

2014 ◽  
Vol 112 (2) ◽  
pp. 356-364 ◽  
Author(s):  
Hun Su Chu ◽  
Young Soo Kim ◽  
Chan Mu Lee ◽  
Ju Hee Lee ◽  
Won Seok Jung ◽  
...  
Keyword(s):  
Metabolic Engineering ◽  
Inescherichia Coli ◽  
Acid Biosynthesis ◽  
Hydroxypropionic Acid

scholarly journals Metabolic engineering of indole pyruvic acid biosynthesis in Escherichia coli with tdiD

2017 ◽  
Vol 16 (1) ◽  
Author(s):  
Yelin Zhu ◽  
Yan Hua ◽  
Biao Zhang ◽  
Lianhong Sun ◽  
Wenjie Li ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Metabolic Engineering ◽  
Pyruvic Acid ◽  
Acid Biosynthesis

scholarly journals Fatty acid biosynthesis revisited: structure elucidation and metabolic engineering

2015 ◽  
Vol 11 (1) ◽  
pp. 38-59 ◽  
Author(s):  
Joris Beld ◽  
D. John Lee ◽  
Michael D. Burkart
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Metabolic Engineering ◽  
Structure Elucidation ◽  
Fatty Acid Biosynthesis ◽  
Acid Biosynthesis ◽  
Primary Metabolites ◽  
Biosynthetic Machinery

Fatty acids are primary metabolites synthesized by complex, elegant, and essential biosynthetic machinery.

Metabolic engineering and transhydrogenase effects on NADPH availability inescherichia coli

2013 ◽  
Vol 29 (5) ◽  
pp. 1124-1130 ◽  
Author(s):  
Joanna Jan ◽  
Irene Martinez ◽  
Yipeng Wang ◽  
George N. Bennett ◽  
Ka-Yiu San
Keyword(s):  
Metabolic Engineering ◽  
Inescherichia Coli

scholarly journals Bio-based 3-hydroxypropionic Acid: A Review

2017 ◽  
Vol 62 (2) ◽  
pp. 156 ◽  
Author(s):  
Aladár Vidra ◽  
Áron Németh
Keyword(s):  
Metabolic Engineering ◽  
Acrylic Acid ◽  
Methyl Acrylate ◽  
Metabolic Pathways ◽  
Commercial Production ◽  
Genetically Engineered ◽  
High Yield ◽  
Biochemical Pathways ◽  
Genetically Engineered Microorganism ◽  
Hydroxypropionic Acid

3-hydroxypropionic acid is a commercially valuable, important platform chemical. It can serve as a precursor for several key compound, such as acrylic acid, 1,3-propanediol, methyl acrylate, acrylamide, ethyl 3-HP, malonic acid, propiolactone and acrylonitrile. Several microorganisms can produce through a range of metabolic pathways. It is indispensable for the commercial production of 3-HP to use cheap and abundant substrates and also to produce in highly efficient processes which could result high yield, titer and productivity. Because  of the fact, that natural microorganism do not perform these conditions, metabolic engineering and genetically engineered microorganism are widely used for research and production as well. Several metabolic pathways are introduced to utilize glucose or glycerol for 3-HP production. In this overview naturally producer microorganisms, synthetic biochemical pathways, results from the recent years and recovery of 3-HP are detailed.

Metabolic engineering strategies for D-lactate over production inEscherichia coli

2015 ◽  
Vol 91 (3) ◽  
pp. 576-584 ◽  
Author(s):  
Li Zhou ◽  
Wen-jing Cui ◽  
Zhong-mei Liu ◽  
Zhe-min Zhou
Keyword(s):  
Metabolic Engineering ◽  
Inescherichia Coli
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