Evaluation of high-capacity cation exchange chromatography for direct capture of monoclonal antibodies from high-titer cell culture processes

2014 ◽  
Vol 111 (7) ◽  
pp. 1354-1364 ◽  
Author(s):  
Yinying Tao ◽  
Aladein Ibraheem ◽  
Lynn Conley ◽  
Douglas Cecchini ◽  
Sanchayita Ghose
Keyword(s):  
Cell Culture ◽  
Monoclonal Antibodies ◽  
Cation Exchange ◽  
High Titer ◽  
High Capacity ◽  
Exchange Chromatography ◽  
Cation Exchange Chromatography ◽  
Direct Capture

Cation exchange chromatography performed in overloaded mode is effective in removing viruses during the manufacturing of monoclonal antibodies

2019 ◽  
Vol 35 (5) ◽  
Author(s):  
Yumiko Masuda ◽  
Masashi Tsuda ◽  
Chie Hashikawa‐Muto ◽  
Yusuke Takahashi ◽  
Koichi Nonaka ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Cation Exchange ◽  
Exchange Chromatography ◽  
Cation Exchange Chromatography

scholarly journals The use of native cation-exchange chromatography to study aggregation and phase separation of monoclonal antibodies

2010 ◽  
Vol 19 (6) ◽  
pp. 1191-1204 ◽  
Author(s):  
Shuang Chen ◽  
Hollis Lau ◽  
Yan Brodsky ◽  
Gerd R. Kleemann ◽  
Ramil F. Latypov
Keyword(s):  
Monoclonal Antibodies ◽  
Phase Separation ◽  
Cation Exchange ◽  
Exchange Chromatography ◽  
Cation Exchange Chromatography
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