Sedimentation studies of DNA in concentrated solutions of magnesium salts

Biopolymers ◽  
1971 ◽  
Vol 10 (6) ◽  
pp. 991-1001 ◽  
Author(s):  
B. R. Vijayendran ◽  
R. D. Vold
1979 ◽  
Vol 42 (02) ◽  
pp. 603-610 ◽  
Author(s):  
J H Adams ◽  
J R A Mitchell

SummaryThe ability of potential anti-thrombotic agents to modify platelet-thrombus formation in injured cerebral arteries in the rabbit was tested. Low doses of heparin were without effect, while higher doses produced variable suppression of white body formation but at the expense of bleeding. Aspirin did not inhibit white body formation but another non-steroid anti-inflammatory agent, flurbiprofen was able to do so, as was the anti-gout agent, sulphinpyrazone. Magnesium salts both topically and parenterally, suppressed thrombus formation and increased the concentration of ADP which was required to initiate thrombus production at minor injury sites.


2020 ◽  
Vol 04 ◽  
Author(s):  
Vigen G. Barkhudaryan ◽  
Gayane V. Ananyan ◽  
Nelli H. Karapetyan

Background: The processes of destruction and crosslinking of macromolecules occur simultaneously under the influence of ultraviolet (UV) radiation in synthetic polymers, dry DNA and their concentrated solutions. Objective: The effect of UV radiation on calf thymus DNA in dilute solutions subjected to UV- irradiation was studied in this work. Method: The calf thymus DNA was studied in dilute solutions using viscometry, absorption spectroscopy and electrophoresis. Results: It was shown, that at a low concentration of DNA in the buffer solution ([DNA] = 85 μg / ml) under the influence of UV radiation, the processes of destruction of macromolecules and an increase in their flexibility predominate, which is accompanied by a gradual decrease in the viscosity of their solution. In addition, due to the low concentration of the solution, intramolecular crosslinking of macromolecules predominates, which also reduces their size and, consequently, the viscosity of the solution. Conclusion: It was concluded, that in dilute DNA solutions, due to the predominance of the processes of intramolecular crosslinking of macromolecules over intermolecular, only constant processes of decreasing the sizes of DNA macromolecules occur. As a result, its solubility remains virtually unchanged during UV irradiation. The described comments are also excellently confirmed by the results of absorption spectroscopy and electrophoresis


1984 ◽  
Vol 49 (5) ◽  
pp. 1109-1115
Author(s):  
Jindřich Novák ◽  
Zdeněk Kodejš ◽  
Ivo Sláma

The density, viscosity, and electrical conductivity of highly concentrated solutions of ammonium nitrate in dimethyl sulphoxide have been determined over the temperature range 10-60 °C and the concentration range 7-50 mol% of the salt. The variations in the quantities as a function of temperature and concentration have been correlated by empirical equations. A comparison is made between the transport properties for the present system, aqueous solutions of ammonium nitrate, and calcium nitrate solutions in dimethyl sulphoxide.


2009 ◽  
Vol 152 (1-2) ◽  
pp. 48-88 ◽  
Author(s):  
Martin Z. Bazant ◽  
Mustafa Sabri Kilic ◽  
Brian D. Storey ◽  
Armand Ajdari

RSC Advances ◽  
2021 ◽  
Vol 11 (18) ◽  
pp. 10929-10934
Author(s):  
Chuangui Cao ◽  
Zhihui Zhao ◽  
Yong Qi ◽  
Hui Peng ◽  
Kuanjun Fang ◽  
...  

The solvent, DEA, reduces the dye aggregation that may be caused by the weak hydrogen bonding and relatively smaller steric hindrance effect.


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