An autonomously self-assembling dendritic DNA nanostructure for target DNA detection

2012 ◽  
Vol 8 (2) ◽  
pp. 221-227 ◽  
Author(s):  
Harish Chandran ◽  
Abhijit Rangnekar ◽  
Geetha Shetty ◽  
Erik A. Schultes ◽  
John H. Reif ◽  
...  
Keyword(s):  
Dna Detection ◽  
Dna Nanostructure ◽  
Self Assembling ◽  
Target Dna

A Long and Reversibly Self‐Assembling 1D DNA Nanostructure Built from Triplex and Quadruplex Hybrid Tiles

2021 ◽  
Vol 133 (16) ◽  
pp. 8804-8809
Author(s):  
Prince Kumar Lat ◽  
Clayton W. Schultz ◽  
Hua‐Zhong Yu ◽  
Dipankar Sen
Keyword(s):  
Dna Nanostructure ◽  
Self Assembling

The Fabrication of 2D Cu-Based MOF Nanosheets for DNA Detection

2019 ◽  
Vol 72 (12) ◽  
pp. 939
Author(s):  
Xuan Qi ◽  
Lingyu Xia ◽  
Yunong Li ◽  
Tieqiang Wang ◽  
Xuemin Zhang ◽  
...  
Keyword(s):  
Detection Limit ◽  
Dna Detection ◽  
Metal Organic Framework ◽  
Linear Range ◽  
Spray Method ◽  
Target Dna ◽  
Metal Organic ◽  
Dna Mixture ◽  
2D Structure ◽  
Application Scope

The Cu-based metal–organic framework (MOF) analogues, copper 1,4-benzenedicarboxylate (CuBDC), copper 2,6-naphthalenedicarboxylate (Cu(2,6-NDC)), and copper 1,4-naphthalenedicarboxylate (Cu(1,4-NDC)) MOF nanosheets, are prepared as biosensor nanoplatforms for DNA detection by a spray method. With the ultrathin 2D structure, the fabricated MOF nanosheets exhibited better detection of target DNA, in particular when compared with the corresponding 3D MOF bulky crystals, when used as a DNA biosensor platform. The Cu(1,4-NDC) nanosheets display a distinct sensitivity with a detection limit of 0.3nM and linear range of 0–20nM, and selectivity for the target DNA or target DNA mixture. The feasible biosensor nanoplatform composed of 2D MOF nanosheets broadens the application scope of MOF nanosheets.

A dual-cycling biosensor for target DNA detection based on the toehold-mediated strand displacement reaction and exonuclease III assisted amplification

2018 ◽  
Vol 42 (6) ◽  
pp. 4714-4718 ◽  
Author(s):  
Yu Ling ◽  
Xiao Fang Zhang ◽  
Xiao Hui Chen ◽  
Li Liu ◽  
Xiao Hu Wang ◽  
...  
Keyword(s):  
Dna Detection ◽  
Dna Biosensor ◽  
Displacement Reaction ◽  
Strand Displacement ◽  
Exonuclease Iii ◽  
Target Dna ◽  
Strand Displacement Reaction

Based on the toehold-mediated strand displacement reaction and exonuclease III assisted amplification, a sensitive and simple target DNA biosensor was established.

scholarly journals Optical Thickness-Encoded Suspension Array for High-Throughput Multiplexed Gene Detection

Sensors ◽  
2019 ◽  
Vol 19 (24) ◽  
pp. 5425
Author(s):  
Huiying Ma ◽  
Xuejing Chen ◽  
Bangrong Lu ◽  
Yanhong Ji
Keyword(s):  
Optical Thickness ◽  
Dna Detection ◽  
High Specificity ◽  
Analyte Concentration ◽  
Gene Detection ◽  
Suspension Array ◽  
Dna Molecule ◽  
Target Dna ◽  
Good Repeatability ◽  
Encoding Method

We proposed a coding and decoding method of suspension array (SA) based on micro-quartz pieces (MQPs) with different optical thicknesses. The capture probes (cDNA) were grafted onto the surfaces of MQPs and specifically recognized and combined with the partial sequence of the target DNA (tDNA) to form a MQP-cDNA-tDNA complex. Quantum dot-labeled signal probes were then used to specifically recognize and bind another portion of the tDNA in the complex to form a double-probe sandwich structure. This optical thickness-encoded SA can be decoded and detected by a dual-wavelength digital holographic phase fluorescence microscope system. We conducted a series of DNA molecule detection experiments by using this encoding method. Control experiments confirmed the specificity of optical thickness-encoded SA in DNA detection. The concentration gradient experiments then demonstrated the response of the MQPs based SA to analyte concentration. Finally, we used the encoding method to detect three types of DNA in a single sample and confirmed the feasibility of the proposed optical thickness-encoded SA in multiplexed DNA detection. The detection results are stable, and the detection exhibits high specificity and good repeatability.

Fabrication of fluorescence enhancement of quantum dots on a gold colloid formed film for oligonucleotide DNA detection

2017 ◽  
Vol 9 (3) ◽  
pp. 434-442 ◽  
Author(s):  
Jie Yang ◽  
Ji-Tao Song ◽  
Wei Hu ◽  
Yan Huang ◽  
Li-Juan Deng ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Quantum Dot ◽  
Fluorescence Enhancement ◽  
Dna Detection ◽  
Gold Colloid ◽  
Target Dna

This paper reported a method based on metal-enhanced quantum dot fluorescence on a gold colloid formed film for target DNA detection.

Quantum material accompanied nonenzymatic cascade amplification for ultrasensitive photoelectrochemical DNA sensing

2017 ◽  
Vol 5 (37) ◽  
pp. 7775-7780 ◽  
Author(s):  
Guangming Wen ◽  
Xiaojie Yang ◽  
Yongzhao Wang
Keyword(s):  
Quantum Dots ◽  
Signal Amplification ◽  
Dna Detection ◽  
Dna Sensing ◽  
Target Dna ◽  
Cascade Amplification

A novel cascade photoelectrochemical (PEC) signal amplification sensing strategy was designed and applied in target DNA detection by introducing quantum dots (QD) as the accompanying tag.

Sign in / Sign up

Export Citation Format

Share Document